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Current Allergy and Asthma Reports
Erschienen in: Current Allergy and Asthma Reports 6/2012

01.12.2012 | OTITIS (DP SKONER, SECTION EDITOR)

Current Knowledge of the Genetics of Otitis Media

verfasst von: Lena Hafrén, Erna Kentala, Elisabet Einarsdottir, Juha Kere, Petri S. Mattila

Erschienen in: Current Allergy and Asthma Reports | Ausgabe 6/2012

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Abstract

Otitis media is one of the most common childhood infections leading to doctor’s visits and a leading cause of antibiotic prescriptions in children. Twin and family studies have confirmed that the predisposition of developing a bacterial middle ear infection is genetically determined. Several case-control studies have been performed to analyze genes involved in inflammatory processes in search of potential associations. Modern genome-wide association approaches that require no prior assumptions of the involvement of a given gene locus in the risk of otitis media are currently being used to identify otitis media genes, and will hopefully give more detailed information on the pathogenesis of childhood otitis media. That information could be used in finding the high-risk patient, in the prevention of the disease, and in the design of new treatments.
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Metadaten
Titel
Current Knowledge of the Genetics of Otitis Media
verfasst von
Lena Hafrén
Erna Kentala
Elisabet Einarsdottir
Juha Kere
Petri S. Mattila
Publikationsdatum
01.12.2012
Verlag
Current Science Inc.
Erschienen in
Current Allergy and Asthma Reports / Ausgabe 6/2012
Print ISSN: 1529-7322
Elektronische ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-012-0292-1

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