Dantrolene

Excerpt

A 35-year-old woman experienced faintness, while receiving treatment with dantrolene [dantrolene sodium]. She was suffering from muscle cramps associated with localised scleroderma (Parry Romberg syndrome type). She was receiving treatment with prednisolone for the scleroderma. In addition to this, for the alleviation of muscle cramps, she started receiving oral dantrolene at a maximum dose of 75mg. Initially, she complained of mild faintness [duration of treatment to reaction onset not stated], which was considered secondary to her dantrolene therapy. The faintness disappeared in a week and she continued receiving dantrolene therapy, with complete resolution of her muscle cramps at a reduced dose of 37.5 mg/day. …