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Journal of Imaging Informatics in Medicine

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07.09.2022 | Original Paper

Definition of the Region of Interest for the Assessment of Alveolar Bone Repair Using Micro-computed Tomography

verfasst von: Juliana Simeão Borges, Vitor Cardoso Costa, Milena Suemi Irie, Gabriella Lopes de Rezende Barbosa, Rubens Spin-Neto, Priscilla Barbosa Ferreira Soares

Erschienen in: Journal of Imaging Informatics in Medicine | Ausgabe 1/2023

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Abstract

The objective of this study was to evaluate the influence of the extraction socket (distal or lingual root) and the type of region of interest (ROI) definition (manual or predefined) on the assessment of alveolar repair following tooth extraction using micro-computed tomography (micro-CT). The software package used for scanning, reconstruction, reorientation, and analysis of images (NRecon^®, DataViewer^®, CT-Analyzer^®) was acquired through Bruker < https://www.bruker.com > . The sample comprised the micro-CT volumes of seven Wistar rat mandibles, in which the right first molar was extracted. The reconstructed images were analyzed using the extraction sockets, i.e., the distal and intermediate lingual root and the method of ROI definition: manual (MA), central round (CR), and peripheral round (PR). The bone volume fraction (BV/TV) values obtained were analyzed by two-way ANOVA with Tukey’s post hoc test (α = 5%). The distal extraction socket resulted in significantly lower BV/TV values than the intermediate lingual socket for MA (P = 0.001), CR (P < 0.001), and PR (P < 0.001). Regarding the ROI, when evaluating the distal extraction socket, the BV/TV was significantly higher (P < 0.001) for MA than for CR and PR, with a lower BV/TV for CR. However, no significant difference was observed for MA (P = 0.855), CR (P = 0.769), or PR (P = 0.453) in the intermediate lingual extraction socket. The bone neoformation outcome (BV/TV) for alveolar bone repair after tooth extraction is significantly influenced by the ROI and the extraction socket. Using the predefined method with a standardized ROI in the central region of the distal extraction socket resulted in the assessment of bone volume, demonstrating the most critical region of the bone neoformation process.

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Titel: Definition of the Region of Interest for the Assessment of Alveolar Bone Repair Using Micro-computed Tomography
verfasst von: Juliana Simeão Borges
Vitor Cardoso Costa
Milena Suemi Irie
Gabriella Lopes de Rezende Barbosa
Rubens Spin-Neto
Priscilla Barbosa Ferreira Soares
Publikationsdatum: 07.09.2022
Verlag: Springer International Publishing
Erschienen in: Journal of Imaging Informatics in Medicine / Ausgabe 1/2023
Print ISSN: 2948-2925
Elektronische ISSN: 2948-2933
DOI: https://doi.org/10.1007/s10278-022-00693-w

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