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29.07.2020 | Original Research

Designing a Primary Care–Based Deprescribing Intervention for Patients with Dementia and Multiple Chronic Conditions: a Qualitative Study

verfasst von: Ariel R. Green, MD, MPH, PhD, Cynthia M. Boyd, MD, MPH, Kathy S. Gleason, PhD, Leslie Wright, MA, Courtney R. Kraus, MSPH, Ruth Bedoy, BS, Bianca Sanchez, BS, Jonathan Norton, BS, Orla C. Sheehan, MD, PhD, Jennifer L. Wolff, PhD, Emily Reeve, BPharm(Hons) PhD, Matthew L. Maciejewski, PhD, Linda A. Weffald, PharmD, Elizabeth A. Bayliss, MD, MSPH

Erschienen in: Journal of General Internal Medicine | Ausgabe 12/2020

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Abstract

Background

Patients with dementia and multiple chronic conditions (MCC) frequently experience polypharmacy, increasing their risk of adverse drug events.

Objectives

To elucidate patient, family, and physician perspectives on medication discontinuation and recommended language for deprescribing discussions in order to inform an intervention to increase awareness of deprescribing among individuals with dementia and MCC, family caregivers and primary care physicians. We also explored participant views on culturally competent approaches to deprescribing.

Design

Qualitative approach based on semi-structured interviews with patients, caregivers, and physicians.

Participants

Patients aged ≥ 65 years with claims-based diagnosis of dementia, ≥ 1 additional chronic condition, and ≥ 5 chronic medications were recruited from an integrated delivery system in Colorado and an academic medical center in Maryland. We included caregivers when present or if patients were unable to participate due to severe cognitive impairment. Physicians were recruited within the same systems and through snowball sampling, targeting areas with large African American and Hispanic populations.

Approach

We used constant comparison to identify and compare themes between patients, caregivers, and physicians.

Key Results

We conducted interviews with 17 patients, 16 caregivers, and 16 physicians. All groups said it was important to earn trust before deprescribing, frame deprescribing as routine and positive, align deprescribing with goals of dementia care, and respect caregivers’ expertise. As in other areas of medicine, racial, ethnic, and language concordance was important to patients and caregivers from minority cultural backgrounds. Participants favored direct-to-patient educational materials, support from pharmacists and other team members, and close follow-up during deprescribing. Patients and caregivers favored language that explained deprescribing in terms of altered physiology with aging. Physicians desired communication tips addressing specific clinical situations.

Conclusions

Culturally sensitive communication within a trusted patient-physician relationship supplemented by pharmacists, and language tailored to specific clinical situations may support deprescribing in primary care for patients with dementia and MCC.

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Titel: Designing a Primary Care–Based Deprescribing Intervention for Patients with Dementia and Multiple Chronic Conditions: a Qualitative Study
verfasst von: Ariel R. Green, MD, MPH, PhD
Cynthia M. Boyd, MD, MPH
Kathy S. Gleason, PhD
Leslie Wright, MA
Courtney R. Kraus, MSPH
Ruth Bedoy, BS
Bianca Sanchez, BS
Jonathan Norton, BS
Orla C. Sheehan, MD, PhD
Jennifer L. Wolff, PhD
Emily Reeve, BPharm(Hons) PhD
Matthew L. Maciejewski, PhD
Linda A. Weffald, PharmD
Elizabeth A. Bayliss, MD, MSPH
Publikationsdatum: 29.07.2020
Verlag: Springer International Publishing
Erschienen in: Journal of General Internal Medicine / Ausgabe 12/2020
Print ISSN: 0884-8734
Elektronische ISSN: 1525-1497
DOI: https://doi.org/10.1007/s11606-020-06063-y

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