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European Journal of Nuclear Medicine and Molecular Imaging

Erschienen in:

01.03.2008 | Image of the month

Discrepancy between glucose metabolism and sympathetic nerve terminals in a patient with metastatic paraganglioma

verfasst von: Kambiz Rahbar, Peter Kies, Lars Stegger, Kai Uwe Juergens, Matthias Weckesser

Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging | Ausgabe 3/2008

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Excerpt

There are several radiotracers currently available for detecting tumors of the sympathetic nervous system. [¹²³I]-meta-iodobenzylguanidine (MIBG) is commonly used with planar imaging and single photon emission computerised tomography (SPECT) and depicts presynaptic noradrenalin reuptake. Alternatively, the positron emitting radiopharmaceutical [¹¹C]-meta-hydroxyephedrine (mHED) may be used together with positron emission tomography (PET) to measure the same molecular process; the superior imaging characteristics may allow to detect tumours with a higher sensitivity compared to MIBG-SPECT [1]. …

Franzius C, Hermann K, Weckesser M, Kopka K, Juergens KU, Vormoor J, et al. Whole-body PET/CT with ¹¹C-meta-hydroxyephedrine in tumors of the sympathetic nervous system: feasibility study and comparison with 123I-MIBG SPECT/CT. J Nucl Med 2006;47:1635–42.PubMed

Mamede M, Carrasquillo JA, Chen CC, Del Corral P, Whatley M, Ilias I, et al. Discordant localization of 2-[18F]-fluoro-2-deoxy-d-glucose in 6-[18F]-fluorodopamine- and [(123)I]-metaiodobenzylguanidine-negative metastatic pheochromocytoma sites. Nucl Med Commun 2006;27:31–6.PubMedCrossRef

Titel: Discrepancy between glucose metabolism and sympathetic nerve terminals in a patient with metastatic paraganglioma
verfasst von: Kambiz Rahbar
Peter Kies
Lars Stegger
Kai Uwe Juergens
Matthias Weckesser
Publikationsdatum: 01.03.2008
Verlag: Springer-Verlag
Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging / Ausgabe 3/2008
Print ISSN: 1619-7070
Elektronische ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-007-0646-4

Springer Medizin

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