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15.02.2019 | Original Article

Do electrical current and laser therapies improve bone remodeling during an orthodontic treatment with corticotomy?

verfasst von: Ewerton Zaniboni, Leonardo Bagne, Thaís Camargo, Maria Esméria Corezola do Amaral, Maira Felonato, Thiago Antônio Moretti de Andrade, Gláucia Maria Tech dos Santos, Guilherme Ferreira Caetano, Marcelo Augusto Marreto Esquisatto, Milton Santamaria Jr, Fernanda Aparecida Sampaio Mendonça

Erschienen in: Clinical Oral Investigations | Ausgabe 11/2019

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Abstract

Objectives

Evaluate the bone remodeling during orthodontic movement with corticotomy when submitted to low-intensity electrical stimulation application (microcurrent—MC) and low-level laser therapy (LLLT).

Material and methods

One hundred and fifty Wistar rats were divided into the following 5 groups: (C) submitted to tooth movement; (Cort) tooth movement/corticotomy; (Cort-L) tooth movement/corticotomy/laser AsGaAl 808 nm (4.96J/50s); (Cort-Mc) tooth movement/corticotomy/microcurrent (10 μA/5 min); (Cort-L-Mc) tooth movement/corticotomy and laser/microcurrent alternated. Inflammation, angiogenesis, and osteogenesis were evaluated in the periodontal ligament (PDL) and alveolar bone on the 7th, 14th, and 21st days of orthodontic movement.

Results

The quantification of inflammatory infiltrate, angiogenesis and expression of TGF-β1, VEGF, and collagen type I were favorably modulated by the application of therapies such as low-level laser therapy (LLLT), MC, or both combined. However, electrical stimulation increased fibroblasts, osteoclasts and RANK numbers, birefringent collagen fiber organization, and BMP-7 and IL-6 expression.

Conclusions

Low-level laser therapy (LLLT) and MC application both improved the process of bone remodeling during orthodontic treatment with corticotomy. Still, electrical current therapy promoted a more effective tooth displacement but presented expected root resorption similar to all experimental treatments.

Clinical relevance

It is important to know the effects of minimally invasive therapies on cellular and molecular elements involved in the bone remodeling of orthodontic treatment associated with corticotomy surgery, in order to reduce the adverse effects in the use of this technique and to establish a safer clinical routine.

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Titel: Do electrical current and laser therapies improve bone remodeling during an orthodontic treatment with corticotomy?
verfasst von: Ewerton Zaniboni
Leonardo Bagne
Thaís Camargo
Maria Esméria Corezola do Amaral
Maira Felonato
Thiago Antônio Moretti de Andrade
Gláucia Maria Tech dos Santos
Guilherme Ferreira Caetano
Marcelo Augusto Marreto Esquisatto
Milton Santamaria Jr
Fernanda Aparecida Sampaio Mendonça
Publikationsdatum: 15.02.2019
Verlag: Springer Berlin Heidelberg
Erschienen in: Clinical Oral Investigations / Ausgabe 11/2019
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-019-02845-9

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