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Erschienen in: Quality of Life Research 9/2020

18.04.2020

Does exercise program of endurance and strength improve health-related quality of life in persons living with HIV-related distal symmetrical polyneuropathy? A randomized controlled trial

verfasst von: Abdulsalam Mohammed Yakasai, Sonill Sooknunan Maharaj, Bashir Kaka, Musa Sani Danazumi

Erschienen in: Quality of Life Research | Ausgabe 9/2020

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Abstract

Background

The most common HIV neurological comorbidity, Distal Symmetrical Peripheral Neuropathy (DSPN), is characterized by severe symptoms and reduced quality of life. Exercise has consistently been mentioned as one of the non-pharmacological therapies for the rehabilitation of individuals with HIV, but little is known about an exercise program to recommend to people living with HIV (PLWHIV)-related DSPN. The purpose of this study was to investigate the effectiveness of aerobic (AE) or progressive resisted exercise (PRE) on quality of life (QOL) in a person living with HIV-related DSPN.

Method

A randomized controlled trial was conducted with 136 persons living with HIV-related Neuropathy, including 6 domains of QOL within WHOQOL-BREF, 45 in the AE (used ergometer), 44 in the PRE (used quadriceps bench), and 47 in the control group (CG). The outcome measures (QOL) data were analyzed using the inferential statistic of Friedman for within-group with post hoc analysis of Wilcoxon signed Test. A Kruskal–Wallis test was carried out for between-groups with post hoc analysis of Mann–Whitney to find where significant differences exist.

Results

The results indicated significant differences within experimental groups in all six domains p < 0.05. Similarly, the result indicated significant differences within the CG in Physical, level of independence, and Spirituality/Religions domains (p = 0.002, p = 0.035, p = 0.006). However, the results indicated significant differences between experimental groups and CG.

Conclusion

These findings indicated that strength and endurance exercise of moderate intensity have a positive effect on QOL in PLWHIV-related DSPN.
Clinical trial No. http://​apps.​who.​int/​trialsearch/​default.​aspx (PACTR201707002173240).
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Metadaten
Titel
Does exercise program of endurance and strength improve health-related quality of life in persons living with HIV-related distal symmetrical polyneuropathy? A randomized controlled trial
verfasst von
Abdulsalam Mohammed Yakasai
Sonill Sooknunan Maharaj
Bashir Kaka
Musa Sani Danazumi
Publikationsdatum
18.04.2020
Verlag
Springer International Publishing
Erschienen in
Quality of Life Research / Ausgabe 9/2020
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-020-02500-x

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