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Annals of Behavioral Medicine
Erschienen in: Annals of Behavioral Medicine 1/2011

01.02.2011 | Original Article

Education and Levels of Salivary Cortisol Over the Day in US Adults

verfasst von: Jennifer B. Dowd, Ph.D., Nalini Ranjit, Ph.D., D. Phuong Do, Ph.D., Elizabeth A. Young, Ph.D., James S. House, Ph.D., George A. Kaplan, Ph.D.

Erschienen in: Annals of Behavioral Medicine | Ausgabe 1/2011

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Abstract

Background

Dysregulation of the hypothalamic–pituitary–adrenal axis is hypothesized to be an important pathway linking socioeconomic position and chronic disease.

Purpose

This paper tests the association between education and the diurnal rhythm of salivary cortisol.

Methods

Up to eight measures of cortisol (mean of 5.38 per respondent) over 2 days were obtained from 311 respondents, aged 18–70, drawn from the 2001–2002 Chicago Community Adult Health Study. Multi-level models with linear splines were used to estimate waking level, rates of cortisol decline, and area-under-the-curve over the day, by categories of education.

Results

Lower education (0–11 years) was associated with lower waking levels of cortisol, but not the rate of decline of cortisol, resulting in a higher area-under-the-curve for more educated respondents throughout the day.

Conclusions

This study found evidence of lower cortisol exposure among individuals with less education and thus does not support the hypothesis that less education is associated with chronic over-exposure to cortisol.
Literatur
1.
Adler NE, Boyce WT, Chesney MA, Folkman S, Syme SL. Socioeconomic inequalities in health: No easy solution. Journal of the American Medical Association 1993;269:3140–5.CrossRefPubMed
2.
Kaplan GA HM, Syme SL, Minkler M, Winkleby M. Socioeconomic status and health. Am J Prev Med 1987;3:125–29.
3.
Kristenson M, Eriksen HR, Sluiter JK, Starke D, Ursin H. Psychobiological mechanisms of socioeconomic differences in health. Social Science & Medicine 2004;58:1511–22.CrossRef
4.
Almeida DM, Neupert SD, Banks SR, Serido J. Do daily stress processes account for socioeconomic health disparities? J Gerontol B Psychol Sci Soc Sci 2005;60:S34–9.
5.
6.
Cacioppo JT, Kiecolt-Glaser JK, Malarkey WB, Laskowski BF, Rozlog LA, Poehlmann KM, Burleson MH, Glaser R. Autonomic and glucocorticoid associations with the steady-state expression of latent Epstein–Barr virus. Hormones and Behavior 2002;42:32–41.CrossRefPubMed
7.
Roberge C, Carpentier AC, Langlois M-F, Baillargeon J-P, Ardilouze J-L, Maheux P, Gallo-Payet N. Adrenocortical dysregulation as a major player in insulin resistance and onset of obesity. Am J Physiol Endocrinol Metab 2007;293:E1465–78.CrossRefPubMed
8.
Lupien SJ, de Leon M, de Santi S, Convit A, Tarshish C, Nair NPV, Thakur M, McEwen BS, Hauger RL, Meaney MJ. Cortisol levels during human aging predict hippocampal atrophy and memory deficits. Nat Neurosci 1998;1:69–73.CrossRefPubMed
9.
Pruessner JC, Wolf OT, Hellhammer DH, Buske-Kirschbaum A, von Auer K, Jobst S, Kaspers F, Kirschbaum C. Free cortisol levels after awakening: A reliable biological marker for the assessment of adrenocortical activity. Life Sciences 1997;61:2539–49.CrossRefPubMed
10.
Adam EK, Hawkley LC, Kudielka BM, Cacioppo JT. Day-to-day dynamics of experience-cortisol associations in a population-based sample of older adults. PNAS 2006;103:17058–63.CrossRefPubMed
11.
Young EA, Abelson J, Lightman SL. Cortisol pulsatility and its role in stress regulation and health. Frontiers in Neuroendocrinology 2004;25:69–76.CrossRefPubMed
12.
Hellhammer J, Fries E, Schweisthal OW, Schlotz W, Stone AA, Hagemann D. Several daily measurements are necessary to reliably assess the cortisol rise after awakening: State- and trait components. Psychoneuroendocrinology 2007;32:80–6.CrossRefPubMed
13.
Hruschka DJ, Kohrt BA, Worthman CM. Estimating between- and within-individual variation in cortisol levels using multilevel models. Psychoneuroendocrinology 2005;30:698–714.CrossRefPubMed
14.
Dowd JB, Simanek AM, Aiello AE. Socio-economic status, cortisol and allostatic load: A review of the literature. Int J Epidemiol 2009;38(5):1297–309
15.
Steptoe A, Kunz-Ebrecht S, Owen N, Feldman PJ, Willemsen G, Kirschbaum C, Marmot M. Socioeconomic status and stress-related biological responses over the working day. Psychosom Med 2003;65:461–70.CrossRefPubMed
16.
Brandtstadter J, Baltes-Gotz B, Kirschbaum C, Hellhammer D. Developmental and personality correlates of adrenocortical activity as indexed by salivary cortisol: Observations in the age range of 35 to 65 years. Journal of Psychosomatic Research 1991;35:173–85.CrossRefPubMed
17.
Li L, Power C, Kelly S, Kirschbaum C, Hertzman C. Life-time socio-economic position and cortisol patterns in mid-life. Psychoneuroendocrinology 2007;32:824–33.CrossRefPubMed
18.
Gustafsson PE, Janlert U, Theorell T, Hammarstrom A. Life-course socioeconomic trajectories and diurnal cortisol regulation in adulthood. Psychoneuroendocrinology 2010;35:613–23.CrossRefPubMed
19.
Cohen S, Schwartz JE, Epel E, Kirschbaum C, Sidney S, Seeman T. Socioeconomic status, race, and diurnal cortisol decline in the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Psychosom Med 2006;68:41–50.CrossRefPubMed
20.
Cohen S, Doyle WJ, Baum A. Socioeconomic status is associated with stress hormones. Psychosom Med 2006;68:414–20.CrossRefPubMed
21.
Ranjit N, Young EA, Kaplan GA. Material hardship alters the diurnal rhythm of salivary cortisol. Int J Epidemiol 2005;34:1138–43.CrossRefPubMed
22.
Hajat A, Diez-Roux A, Franklin TG, Seeman T, Shrager S, Ranjit N, Castro C, Watson K, Sanchez B, Kirschbaum C. Socioeconomic and race/ethnic differences in daily salivary cortisol profiles: The Multi-Ethnic Study of Atherosclerosis. Psychoneuroendocrinology 2010;35:932–43.CrossRefPubMed
23.
Ranjit N, Young EA, Raghunathan TE, Kaplan GA. Modeling cortisol rhythms in a population-based study. Psychoneuroendocrinology 2005;30:615–24.CrossRefPubMed
24.
Raudenbush SW, Sampson RJ. Ecometrics: Toward a science of assessing ecological settings, with application to the systematic social observation of neighborhoods. Sociological Methodology 1999;29:1–41.CrossRef
25.
Morenoff JD, House JS, Hansen BB, Williams DR, Kaplan GA, Hunte HE. Understanding social disparities in hypertension prevalence, awareness, treatment, and control: The role of neighborhood context. Social Science & Medicine 2007;65:1853–66.CrossRef
26.
Galea S, Tracy M. Participation rates in epidemiologic studies. Annals of Epidemiology 2007;17:643–53.CrossRefPubMed
27.
Kohout FJ, Berkman LF, Evans DA, Cornoni-Huntley J. Two shorter forms of the CES-D (Center for Epidemiological Studies Depression) depression symptoms index. J Aging Health 1993;5:179–93.CrossRefPubMed
28.
Radloff LS. The CES-D scale: A self-report depression scale for research in the general population. applied psychological measurement 1977;1:385–401.CrossRef
29.
Kunz-Ebrecht SR, Kirschbaum C, Marmot M, Steptoe A. Differences in cortisol awakening response on work days and weekends in women and men from the Whitehall II cohort. Psychoneuroendocrinology 2004;29:516–28.CrossRefPubMed
30.
Decker SA. Salivary cortisol and social status among Dominican men. Horm Behav 2000;38:29–38.CrossRefPubMed
31.
Miller GE, Chen E, Zhou ES. If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-adrenocortical axis in humans. Psychological Bulletin 2007;133:25–45.CrossRefPubMed
32.
Steptoe A, Siegrist J, Kirschbaum C, Marmot M. Effort—reward imbalance, overcommitment, and measures of cortisol and blood pressure over the working day. Psychosom Med 2004;66:323–9.CrossRefPubMed
33.
Lupien SJ, King S, Meaney MJ, McEwen BS. Can poverty get under your skin? basal cortisol levels and cognitive function in children from low and high socioeconomic status. Dev Psychopathol 2001;13:653–76.CrossRef
34.
Kunz-Ebrecht SR, Kirschbaum C, Steptoe A. Work stress, socioeconomic status and neuroendocrine activation over the working day. Social Science & Medicine 2004;58:1523–30.CrossRef
35.
Evolahti A, Hultcrantz M, Collins A. Women’s work stress and cortisol levels: A longitudinal study of the association between the psychosocial work environment and serum cortisol. Journal of Psychosomatic Research 2006;61:645–52.CrossRefPubMed
36.
Adam EK, Gunnar MR. Relationship functioning and home and work demands predict individual differences in diurnal cortisol patterns in women. Psychoneuroendocrinology 2001;26:189–208.CrossRefPubMed
Metadaten
Titel
Education and Levels of Salivary Cortisol Over the Day in US Adults
verfasst von
Jennifer B. Dowd, Ph.D.
Nalini Ranjit, Ph.D.
D. Phuong Do, Ph.D.
Elizabeth A. Young, Ph.D.
James S. House, Ph.D.
George A. Kaplan, Ph.D.
Publikationsdatum
01.02.2011
Verlag
Springer-Verlag
Erschienen in
Annals of Behavioral Medicine / Ausgabe 1/2011
Print ISSN: 0883-6612
Elektronische ISSN: 1532-4796
DOI
https://doi.org/10.1007/s12160-010-9224-2

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