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Erschienen in: Obesity Surgery 12/2018

03.08.2018 | Original Contributions

Endoscopic Management of Post-bariatric Surgery Fistula: a Tertiary Care Center Experience

verfasst von: Hedi Benosman, Gabriel Rahmi, Guillaume Perrod, Mathieu Bruzzi, Elia Samaha, Ariane Vienne, Charles André Cuenod, Jean Marc Chevallier, Richard Douard, Christophe Cellier

Erschienen in: Obesity Surgery | Ausgabe 12/2018

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Abstract

Background and Study Aims

Post-laparoscopic sleeve gastrectomy (LSG) fistula is a major complication, responsible for high morbidity. Endoscopic treatment represents an alternative to surgical management, with variable approaches and success rates. In this study, we aimed to evaluate the efficacy of endoscopic treatment in a tertiary care center.

Patients and Methods

Between March 2010 and March 2015, all patients referred to our center for endoscopic treatment of fistula related to laparoscopic sleeve gastrectomy were included. The primary endpoint was defined as a complete closure of the fistula without recurrence within the 2 months.

Results

A total of 26 patients were retrospectively included (73% female). The mean time between fistula diagnosis and first endoscopy was 27.4 days (± 22). Twenty-three (88.4%) patients had a complete fistula closure after endoscopic treatment. The healing delay was 76.4 days (± 42.8), and an average of 3.5 (± 1.4) endoscopic procedures were required. Clinical efficacy was 100% when the endoscopic treatment was performed within the first 3 weeks, or 70% afterwards (p = 0.046). The fistula closure rate was similar between patients with endoscopic drainage (with or without other endoscopic techniques) and patient with closing techniques alone (85.7% vs. 89.5%, respectively).

Conclusion

Endoscopic treatment of fistula after LSG is efficient but requires early procedures within the first 3 weeks. Endoscopic strategies involving closing procedure or drainage procedure seem to be similar, but these data must be confirmed in large prospective clinical studies.
Literatur
1.
Zurück zum Zitat González-Muniesa P, Mártinez-González M-A, Hu FB, et al. Obesity. Nat Rev Dis Primer. 2017;3:17034.CrossRef González-Muniesa P, Mártinez-González M-A, Hu FB, et al. Obesity. Nat Rev Dis Primer. 2017;3:17034.CrossRef
2.
Zurück zum Zitat Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants. Lancet. 2016;387:1377–96. Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants. Lancet. 2016;387:1377–96.
3.
Zurück zum Zitat Lassailly G, Caiazzo R, Buob D, et al. Bariatric surgery reduces features of nonalcoholic steatohepatitis in morbidly obese patients. Gastroenterology. 2015;149:379–88. quiz e15–16CrossRef Lassailly G, Caiazzo R, Buob D, et al. Bariatric surgery reduces features of nonalcoholic steatohepatitis in morbidly obese patients. Gastroenterology. 2015;149:379–88. quiz e15–16CrossRef
4.
Zurück zum Zitat Mathurin P, Hollebecque A, Arnalsteen L, et al. Prospective study of the long-term effects of bariatric surgery on liver injury in patients without advanced disease. Gastroenterology. 2009;137:532–40.CrossRef Mathurin P, Hollebecque A, Arnalsteen L, et al. Prospective study of the long-term effects of bariatric surgery on liver injury in patients without advanced disease. Gastroenterology. 2009;137:532–40.CrossRef
5.
Zurück zum Zitat Rosenthal RJ. International sleeve gastrectomy expert panel consensus statement: best practice guidelines based on experience of >12,000 cases. Surg Obes Relat Dis. 2012;8:8–19.CrossRef Rosenthal RJ. International sleeve gastrectomy expert panel consensus statement: best practice guidelines based on experience of >12,000 cases. Surg Obes Relat Dis. 2012;8:8–19.CrossRef
6.
Zurück zum Zitat Trastulli S, Desiderio J, Guarino S, et al. Laparoscopic sleeve gastrectomy compared with other bariatric surgical procedures: a systematic review of randomized trials. Surg Obes Relat Dis. 2013;9:816–29.CrossRef Trastulli S, Desiderio J, Guarino S, et al. Laparoscopic sleeve gastrectomy compared with other bariatric surgical procedures: a systematic review of randomized trials. Surg Obes Relat Dis. 2013;9:816–29.CrossRef
7.
Zurück zum Zitat Hajj GA, Chemaly R. Fistula following laparoscopic sleeve gastrectomy: a proposed classification and algorithm for optimal management. Obes Surg. 2018;28:656–64.CrossRef Hajj GA, Chemaly R. Fistula following laparoscopic sleeve gastrectomy: a proposed classification and algorithm for optimal management. Obes Surg. 2018;28:656–64.CrossRef
8.
Zurück zum Zitat Jr AZF, DeMaria EJ, Tichansky DS, et al. Experience with over 3,000 open and laparoscopic bariatric procedures: multivariate analysis of factors related to leak and resultant mortality. Surg Endosc. 2004;18:193–7.CrossRef Jr AZF, DeMaria EJ, Tichansky DS, et al. Experience with over 3,000 open and laparoscopic bariatric procedures: multivariate analysis of factors related to leak and resultant mortality. Surg Endosc. 2004;18:193–7.CrossRef
9.
Zurück zum Zitat Boeker C, Mall J, Reetz C, et al. Laparoscopic sleeve gastrectomy: investigation of fundus wall thickness and staple height-an observational cohort study: fundus wall thickness and leaks. Obes Surg. 2017;27:3209–14.CrossRef Boeker C, Mall J, Reetz C, et al. Laparoscopic sleeve gastrectomy: investigation of fundus wall thickness and staple height-an observational cohort study: fundus wall thickness and leaks. Obes Surg. 2017;27:3209–14.CrossRef
10.
Zurück zum Zitat Podnos YD, Jimenez JC, Wilson SE, et al. Complications after laparoscopic gastric bypass: a review of 3464 cases. Arch Surg. 2003;138:957–61.CrossRef Podnos YD, Jimenez JC, Wilson SE, et al. Complications after laparoscopic gastric bypass: a review of 3464 cases. Arch Surg. 2003;138:957–61.CrossRef
11.
Zurück zum Zitat Moszkowicz D, Arienzo R, Khettab I, et al. Sleeve gastrectomy severe complications: is it always a reasonable surgical option? Obes Surg. 2013;23:676–86.CrossRef Moszkowicz D, Arienzo R, Khettab I, et al. Sleeve gastrectomy severe complications: is it always a reasonable surgical option? Obes Surg. 2013;23:676–86.CrossRef
12.
Zurück zum Zitat Bruzzi M, Douard R, Voron T, et al. Open total gastrectomy with Roux-en-Y reconstruction for a chronic fistula after sleeve gastrectomy. Surg Obes Relat Dis. 2016;12:1803–8.CrossRef Bruzzi M, Douard R, Voron T, et al. Open total gastrectomy with Roux-en-Y reconstruction for a chronic fistula after sleeve gastrectomy. Surg Obes Relat Dis. 2016;12:1803–8.CrossRef
13.
Zurück zum Zitat Lorenzo D, Guilbaud T, Gonzalez JM, Benezech A, Dutour A, Boullu S, et al. Endoscopic treatment of fistulas after sleeve gastrectomy: a comparison of internal drainage versus closure. Gastrointest Endosc 2017. Lorenzo D, Guilbaud T, Gonzalez JM, Benezech A, Dutour A, Boullu S, et al. Endoscopic treatment of fistulas after sleeve gastrectomy: a comparison of internal drainage versus closure. Gastrointest Endosc 2017.
14.
Zurück zum Zitat Eisendrath P, Cremer M, Himpens J, et al. Endotherapy including temporary stenting of fistulas of the upper gastrointestinal tract after laparoscopic bariatric surgery. Endoscopy. 2007;39:625–30.CrossRef Eisendrath P, Cremer M, Himpens J, et al. Endotherapy including temporary stenting of fistulas of the upper gastrointestinal tract after laparoscopic bariatric surgery. Endoscopy. 2007;39:625–30.CrossRef
15.
Zurück zum Zitat Serra C, Baltasar A, Andreo L, et al. Treatment of gastric leaks with coated self-expanding stents after sleeve gastrectomy. Obes Surg. 2007;17:866–72.CrossRef Serra C, Baltasar A, Andreo L, et al. Treatment of gastric leaks with coated self-expanding stents after sleeve gastrectomy. Obes Surg. 2007;17:866–72.CrossRef
16.
Zurück zum Zitat Oshiro T, Kasama K, Umezawa A, et al. Successful management of refractory staple line leakage at the esophagogastric junction after a sleeve gastrectomy using the HANAROSTENT. Obes Surg. 2010;20:530–4.CrossRef Oshiro T, Kasama K, Umezawa A, et al. Successful management of refractory staple line leakage at the esophagogastric junction after a sleeve gastrectomy using the HANAROSTENT. Obes Surg. 2010;20:530–4.CrossRef
17.
Zurück zum Zitat Simon F, Siciliano I, Gillet A, et al. Gastric leak after laparoscopic sleeve gastrectomy: early covered self-expandable stent reduces healing time. Obes Surg. 2013;23:687–92.CrossRef Simon F, Siciliano I, Gillet A, et al. Gastric leak after laparoscopic sleeve gastrectomy: early covered self-expandable stent reduces healing time. Obes Surg. 2013;23:687–92.CrossRef
18.
Zurück zum Zitat Aryaie AH, Singer JL, Fayezizadeh M, et al. Efficacy of endoscopic management of leak after foregut surgery with endoscopic covered self-expanding metal stents (SEMS). Surg Endosc. 2017;31:612–7.CrossRef Aryaie AH, Singer JL, Fayezizadeh M, et al. Efficacy of endoscopic management of leak after foregut surgery with endoscopic covered self-expanding metal stents (SEMS). Surg Endosc. 2017;31:612–7.CrossRef
19.
Zurück zum Zitat van den Berg MW, Kerbert AC, van Soest EJ, et al. Safety and efficacy of a fully covered large-diameter self-expanding metal stent for the treatment of upper gastrointestinal perforations, anastomotic leaks, and fistula. Dis Esophagus. 2016;29:572–9.CrossRef van den Berg MW, Kerbert AC, van Soest EJ, et al. Safety and efficacy of a fully covered large-diameter self-expanding metal stent for the treatment of upper gastrointestinal perforations, anastomotic leaks, and fistula. Dis Esophagus. 2016;29:572–9.CrossRef
20.
Zurück zum Zitat Murino A, Arvanitakis M, Le Moine O, et al. Effectiveness of endoscopic management using self-expandable metal stents in a large cohort of patients with post-bariatric leaks. Obes Surg. 2015;25:1569–76.CrossRef Murino A, Arvanitakis M, Le Moine O, et al. Effectiveness of endoscopic management using self-expandable metal stents in a large cohort of patients with post-bariatric leaks. Obes Surg. 2015;25:1569–76.CrossRef
21.
Zurück zum Zitat Bège T, Emungania O, Vitton V, et al. An endoscopic strategy for management of anastomotic complications from bariatric surgery: a prospective study. Gastrointest Endosc. 2011;73:238–44.CrossRef Bège T, Emungania O, Vitton V, et al. An endoscopic strategy for management of anastomotic complications from bariatric surgery: a prospective study. Gastrointest Endosc. 2011;73:238–44.CrossRef
22.
Zurück zum Zitat Surace M, Mercky P, Demarquay J-F, et al. Endoscopic management of GI fistulae with the over-the-scope clip system (with video). Gastrointest Endosc. 2011;74:1416–9.CrossRef Surace M, Mercky P, Demarquay J-F, et al. Endoscopic management of GI fistulae with the over-the-scope clip system (with video). Gastrointest Endosc. 2011;74:1416–9.CrossRef
23.
Zurück zum Zitat Shoar S, Poliakin L, Khorgami Z, et al. Efficacy and safety of the over-the-scope clip (OTSC) system in the management of leak and fistula after laparoscopic sleeve gastrectomy: a systematic review. Obes Surg. 2017;27:2410–8.CrossRef Shoar S, Poliakin L, Khorgami Z, et al. Efficacy and safety of the over-the-scope clip (OTSC) system in the management of leak and fistula after laparoscopic sleeve gastrectomy: a systematic review. Obes Surg. 2017;27:2410–8.CrossRef
24.
Zurück zum Zitat Pequignot A, Fuks D, Verhaeghe P, et al. Is there a place for pigtail drains in the management of gastric leaks after laparoscopic sleeve gastrectomy? Obes Surg. 2012;22:712–20.CrossRef Pequignot A, Fuks D, Verhaeghe P, et al. Is there a place for pigtail drains in the management of gastric leaks after laparoscopic sleeve gastrectomy? Obes Surg. 2012;22:712–20.CrossRef
25.
Zurück zum Zitat Sakran N, Goitein D, Raziel A, et al. Gastric leaks after sleeve gastrectomy: a multicenter experience with 2,834 patients. Surg Endosc. 2013;27:240–5.CrossRef Sakran N, Goitein D, Raziel A, et al. Gastric leaks after sleeve gastrectomy: a multicenter experience with 2,834 patients. Surg Endosc. 2013;27:240–5.CrossRef
26.
Zurück zum Zitat Bouchard S, Eisendrath P, Toussaint E, et al. Trans-fistulary endoscopic drainage for post-bariatric abdominal collections communicating with the upper gastrointestinal tract. Endoscopy. 2016;48:809–16.CrossRef Bouchard S, Eisendrath P, Toussaint E, et al. Trans-fistulary endoscopic drainage for post-bariatric abdominal collections communicating with the upper gastrointestinal tract. Endoscopy. 2016;48:809–16.CrossRef
27.
Zurück zum Zitat Donatelli G, Dumont J-L, Dhumane P, et al. Double pigtail stent insertion for healing of leaks following Roux-en-Y gastric bypass. Our experience (with videos). Obes Surg. 2017;27:530–5.CrossRef Donatelli G, Dumont J-L, Dhumane P, et al. Double pigtail stent insertion for healing of leaks following Roux-en-Y gastric bypass. Our experience (with videos). Obes Surg. 2017;27:530–5.CrossRef
28.
Zurück zum Zitat Donatelli G, Ferretti S, Vergeau BM, et al. Endoscopic internal drainage with enteral nutrition (EDEN) for treatment of leaks following sleeve gastrectomy. Obes Surg. 2014;24:1400–7.CrossRef Donatelli G, Ferretti S, Vergeau BM, et al. Endoscopic internal drainage with enteral nutrition (EDEN) for treatment of leaks following sleeve gastrectomy. Obes Surg. 2014;24:1400–7.CrossRef
29.
Zurück zum Zitat Donatelli G, Dumont J-L, Cereatti F, et al. Endoscopic internal drainage as first-line treatment for fistula following gastrointestinal surgery: a case series. Endosc Int Open. 2016;4:E647–51.CrossRef Donatelli G, Dumont J-L, Cereatti F, et al. Endoscopic internal drainage as first-line treatment for fistula following gastrointestinal surgery: a case series. Endosc Int Open. 2016;4:E647–51.CrossRef
30.
Zurück zum Zitat Puzziferri N, Roshek TB, Mayo HG, et al. Long-term follow-up after bariatric surgery: a systematic review. JAMA. 2014;312:934–42.CrossRef Puzziferri N, Roshek TB, Mayo HG, et al. Long-term follow-up after bariatric surgery: a systematic review. JAMA. 2014;312:934–42.CrossRef
31.
Zurück zum Zitat Souto-Rodríguez R, Alvarez-Sánchez M-V. Endoluminal solutions to bariatric surgery complications: a review with a focus on technical aspects and results. World J Gastrointest Endosc. 2017;9:105–26.CrossRef Souto-Rodríguez R, Alvarez-Sánchez M-V. Endoluminal solutions to bariatric surgery complications: a review with a focus on technical aspects and results. World J Gastrointest Endosc. 2017;9:105–26.CrossRef
32.
Zurück zum Zitat Christophorou D, Valats J-C, Funakoshi N, et al. Endoscopic treatment of fistula after sleeve gastrectomy: results of a multicenter retrospective study. Endoscopy. 2015;47:988–96.CrossRef Christophorou D, Valats J-C, Funakoshi N, et al. Endoscopic treatment of fistula after sleeve gastrectomy: results of a multicenter retrospective study. Endoscopy. 2015;47:988–96.CrossRef
33.
Zurück zum Zitat Donatelli G, Dumont J-L, Cereatti F, et al. Treatment of leaks following sleeve gastrectomy by endoscopic internal drainage (EID). Obes Surg. 2015;25:1293–301.CrossRef Donatelli G, Dumont J-L, Cereatti F, et al. Treatment of leaks following sleeve gastrectomy by endoscopic internal drainage (EID). Obes Surg. 2015;25:1293–301.CrossRef
34.
Zurück zum Zitat Mercky P, Gonzalez J-M, Aimore Bonin E, et al. Usefulness of over-the-scope clipping system for closing digestive fistulas. Dig Endosc. 2015;27:18–24.CrossRef Mercky P, Gonzalez J-M, Aimore Bonin E, et al. Usefulness of over-the-scope clipping system for closing digestive fistulas. Dig Endosc. 2015;27:18–24.CrossRef
35.
Zurück zum Zitat Puig CA, Waked TM, Baron TH, et al. The role of endoscopic stents in the management of chronic anastomotic and staple line leaks and chronic strictures after bariatric surgery. Surg Obes Relat. 2014;10:613–7.CrossRef Puig CA, Waked TM, Baron TH, et al. The role of endoscopic stents in the management of chronic anastomotic and staple line leaks and chronic strictures after bariatric surgery. Surg Obes Relat. 2014;10:613–7.CrossRef
36.
Zurück zum Zitat Rahmi G, Pidial L, Silva AKA, et al. Designing 3D mesenchymal stem cell sheets merging magnetic and fluorescent features: when cell sheet technology meets image-guided cell therapy. Theranostics. 2016;6:739–51.CrossRef Rahmi G, Pidial L, Silva AKA, et al. Designing 3D mesenchymal stem cell sheets merging magnetic and fluorescent features: when cell sheet technology meets image-guided cell therapy. Theranostics. 2016;6:739–51.CrossRef
Metadaten
Titel
Endoscopic Management of Post-bariatric Surgery Fistula: a Tertiary Care Center Experience
verfasst von
Hedi Benosman
Gabriel Rahmi
Guillaume Perrod
Mathieu Bruzzi
Elia Samaha
Ariane Vienne
Charles André Cuenod
Jean Marc Chevallier
Richard Douard
Christophe Cellier
Publikationsdatum
03.08.2018
Verlag
Springer US
Erschienen in
Obesity Surgery / Ausgabe 12/2018
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-018-3432-4

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