Skip to main content
main-content

01.12.2015 | Research article | Ausgabe 1/2015 Open Access

BMC Musculoskeletal Disorders 1/2015

Epidemiological profile of Dupuytren’s disease in Taiwan (Ethnic Chinese): a nationwide population-based study

Zeitschrift:
BMC Musculoskeletal Disorders > Ausgabe 1/2015
Autoren:
Chin-Choon Yeh, Kuo-Feng Huang, Chung-Han Ho, Kuan-Ting Chen, Cheng Liu, Jhi-Joung Wang, Chin-Chen Chu
Wichtige Hinweise

Competing interests

The authors declare that they have no competing interests.

Authors’ contributions

CCY reviewed the literature reviews, designed the study, and drafted the manuscript. CHH participated in the design of the study and did the statistical analysis. KFH, KTC and CL participated in the literature reviews and data interpretation. JJW involved in revising the manuscript and provided administrative technical support. CCC conceived the study, and participated in its design, in the coordination and interpretation of the data, and in the revision of the manuscript. All authors read and approved the final manuscript.

Abstract

Background

The epidemiologic profile of ethnic Chinese patients with Dupuytren’s disease is unknown. We therefore investigated the epidemiology of Dupuytren’s disease using Taiwan’s National Health Insurance Research Database.

Methods

Patients who filed claims for treatment for Dupuytren’s disease between January 2000 and December 2011 were identified in the database. Age- and gender-specific incidences were estimated by dividing the incidence number by population data.

Results

We identified 1,078 patients with Dupuytren’s disease (681 men, 397 women; male/female ratio: 1:1.72). The annual incidence rate ranged from 0.39-0.63/105 for men and 0.14-0.44/105 for women. A trend analysis revealed a rising trend in the annual incidence from 2001 to 2011 (p = 0.0199). The prevalence rate increased steadily from 0.46/105 in 2000 to 4.52/105 in 2011 (p = 0.0186). The mean age at onset was significantly higher in men than in women (60.7 ± 18.4 vs. 53.7 ± 15.5 years). Peak age at onset for men was 70–79 (28.1%) and for women was 50–59 (33.5%). Men > 60 years old had higher incidence rates than did women (incidence rate ratios: 2.0, 4.5, and 6.6 for those 60–69, 70–79, and ≥ 80, respectively). Hypertension (29.6%), diabetes mellitus (21.9%), hyperlipidemia (14.8%), ischemic heart disease (10.5%), and chronic obstructive pulmonary disease (8.0%) were the most common comorbidities.

Conclusions

The incidence and prevalence of Dupuytren’s disease and the male/female ratio were significantly lower in ethnic Chinese than in Western ethnic groups. Moreover, the age at onset was significantly lower in ethnic Chinese women. However, the incidences of three comorbidities (hypertension, diabetes mellitus, and hyperlipidemia) were similar to those in other ethnicities.
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2015

BMC Musculoskeletal Disorders 1/2015 Zur Ausgabe

Neu im Fachgebiet Orthopädie und Unfallchirurgie

21.11.2019 | ACR 2019 | Kongressbericht | Onlineartikel

Anifrolumab bei SLE nun doch mit signifikanten Ergebnissen

21.11.2019 | ACR 2019 | Kongressbericht | Onlineartikel

Handarthrose: Tops und Flops vom ACR-Kongress

21.11.2019 | ACR 2019 | Kongressbericht | Onlineartikel

JAK - selektive Inhibitoren bei RA mit Vorteilen?

21.11.2019 | ACR 2019 | Kongressbericht | Onlineartikel

Erste Daten zur Differentialtherapie der PsA

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Orthopädie und Unfallchirurgie und bleiben Sie gut informiert – ganz bequem per eMail.

Bildnachweise