Erschienen in:
01.12.2010 | Case Report
Etanercept-induced necrotizing crescentic glomerulonephritis in two patients with rheumatoid arthritis
verfasst von:
Kayoko Kaneko, Toshihiro Nanki, Tadashi Hosoya, Fumitaka Mizoguchi, Nobuyuki Miyasaka
Erschienen in:
Modern Rheumatology
|
Ausgabe 6/2010
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Abstract
We present two patients with rheumatoid arthritis (RA) who developed necrotizing crescentic glomerulonephritis (NCGN) during etanercept therapy. Both patients developed proteinuria and hematuria, and one progressed to renal failure. Renal biopsy revealed NCGN. In both patients, nephritis improved following discontinuation of etanercept and administration of prednisolone. Physicians should be aware of etanercept-induced GN in patients with RA on anti-tumor necrosis factor therapy.