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Erschienen in: Clinical Orthopaedics and Related Research® 7/2009

01.07.2009 | Original Article

Etiology of Ankle Osteoarthritis

verfasst von: Victor Valderrabano, MD, PhD, Monika Horisberger, MD, Iain Russell, MD, Hugh Dougall, MD, Beat Hintermann, MD

Erschienen in: Clinical Orthopaedics and Related Research® | Ausgabe 7/2009

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Abstract

The purpose of this study was to evaluate the distribution rate of etiologies leading to ankle arthritis and to quantify and compare the important clinical and radiologic variables among these etiologic groups. We evaluated data from 390 patients (406 ankles) who consulted our center because of painful end-stage ankle osteoarthritis (OA) by using medical history, physical examination, and radiography. Posttraumatic ankle OA was seen in 78% of the cases (n = 318), secondary arthritis in 13% (n = 52), and primary OA in 9% (n = 36). The average American Orthopaedic Foot and Ankle Society (AOFAS) hindfoot score was 38 points (range, 0–74 points), range of motion was 22° (range, 0°−65°), and visual analog scale for pain was 6.8 (range, 2–10). Patients with posttraumatic end-stage ankle OA were younger than patients with primary OA. The average tibiotalar alignment was 88° (range, 51°–116°) and did not differ between the etiologic groups. Our study showed trauma is the main cause of ankle OA and primary OA is rare. In the majority of patients with ankle OA the average tibiotalar alignment is varus regardless of the underlying etiology.
Level of Evidence: Level IV, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence.
Literatur
1.
Zurück zum Zitat Aurich M, Squires GR, Reiner A, Mollenhauer JA, Kuettner KE, Poole AR, Cole AA. Differential matrix degradation and turnover in early cartilage lesions of human knee and ankle joints. Arthritis Rheum. 2005;52:112–119.PubMedCrossRef Aurich M, Squires GR, Reiner A, Mollenhauer JA, Kuettner KE, Poole AR, Cole AA. Differential matrix degradation and turnover in early cartilage lesions of human knee and ankle joints. Arthritis Rheum. 2005;52:112–119.PubMedCrossRef
2.
Zurück zum Zitat Brown TD, Shaw DT. In vitro contact stress distributions in the natural human hip. J Biomech. 1983;16:373–384.PubMedCrossRef Brown TD, Shaw DT. In vitro contact stress distributions in the natural human hip. J Biomech. 1983;16:373–384.PubMedCrossRef
3.
Zurück zum Zitat Coester LM, Saltzman CL, Leupold J, Pontarelli W. Long-term results following ankle arthrodesis for post-traumatic arthritis. J Bone Joint Surg Am. 2001;83:219–228.PubMed Coester LM, Saltzman CL, Leupold J, Pontarelli W. Long-term results following ankle arthrodesis for post-traumatic arthritis. J Bone Joint Surg Am. 2001;83:219–228.PubMed
4.
Zurück zum Zitat DeCoster TA, Willis MC, Marsh JL, Williams TM, Nepola JV, Dirschl DR, Hurwitz SR. Rank order analysis of tibial plafond fractures: does injury or reduction predict outcome? Foot Ankle Int. 1999;20:44–49.PubMed DeCoster TA, Willis MC, Marsh JL, Williams TM, Nepola JV, Dirschl DR, Hurwitz SR. Rank order analysis of tibial plafond fractures: does injury or reduction predict outcome? Foot Ankle Int. 1999;20:44–49.PubMed
5.
Zurück zum Zitat Eger W, Schumacher BL, Mollenhauer J, Kuettner KE, Cole AA. Human knee and ankle cartilage explants: catabolic differences. J Orthop Res. 2002;20:526–534.PubMedCrossRef Eger W, Schumacher BL, Mollenhauer J, Kuettner KE, Cole AA. Human knee and ankle cartilage explants: catabolic differences. J Orthop Res. 2002;20:526–534.PubMedCrossRef
6.
Zurück zum Zitat Elgafy H, Ebraheim NA, Tile M, Stephen D, Kase J. Fractures of the talus: experience of two level 1 trauma centers. Foot Ankle Int. 2000;21:1023–1029.PubMed Elgafy H, Ebraheim NA, Tile M, Stephen D, Kase J. Fractures of the talus: experience of two level 1 trauma centers. Foot Ankle Int. 2000;21:1023–1029.PubMed
7.
Zurück zum Zitat Felson DT. The epidemiology of osteoarthritis: prevalence and risk factors. In: Kuettner KE, Goldberg VM, eds. Osteoarthritis Disorders. Rosemont, IL: American Academy of Orthopaedic Surgeons; 1995:13–24. Felson DT. The epidemiology of osteoarthritis: prevalence and risk factors. In: Kuettner KE, Goldberg VM, eds. Osteoarthritis Disorders. Rosemont, IL: American Academy of Orthopaedic Surgeons; 1995:13–24.
8.
Zurück zum Zitat Gelber AC, Hochberg MC, Mead LA, Wang NY, Wigley FM, Klag MJ. Joint injury in young adults and risk for subsequent knee and hip osteoarthritis. Ann Intern Med. 2000;133:321–328.PubMed Gelber AC, Hochberg MC, Mead LA, Wang NY, Wigley FM, Klag MJ. Joint injury in young adults and risk for subsequent knee and hip osteoarthritis. Ann Intern Med. 2000;133:321–328.PubMed
9.
Zurück zum Zitat Gunther KP, Sturmer T, Sauerland S, Zeissig I, Sun Y, Kessler S, Scharf HP, Brenner H, Puhl W. Prevalence of generalised osteoarthritis in patients with advanced hip and knee osteoarthritis: the Ulm Osteoarthritis Study. Ann Rheum Dis. 1998;57:717–723.PubMedCrossRef Gunther KP, Sturmer T, Sauerland S, Zeissig I, Sun Y, Kessler S, Scharf HP, Brenner H, Puhl W. Prevalence of generalised osteoarthritis in patients with advanced hip and knee osteoarthritis: the Ulm Osteoarthritis Study. Ann Rheum Dis. 1998;57:717–723.PubMedCrossRef
10.
Zurück zum Zitat Harrington KD. Degenerative arthritis of the ankle secondary to long-standing lateral ligament instability. J Bone Joint Surg Am. 1979;61:354–361.PubMed Harrington KD. Degenerative arthritis of the ankle secondary to long-standing lateral ligament instability. J Bone Joint Surg Am. 1979;61:354–361.PubMed
11.
Zurück zum Zitat Hashimoto T, Inokuchi S. A kinematic study of ankle joint instability due to rupture of the lateral ligaments. Foot Ankle Int. 1997;18:729–734.PubMed Hashimoto T, Inokuchi S. A kinematic study of ankle joint instability due to rupture of the lateral ligaments. Foot Ankle Int. 1997;18:729–734.PubMed
12.
Zurück zum Zitat Huch K, Kuettner KE, Dieppe P. Osteoarthritis in ankle and knee joints. Semin Arthritis Rheum. 1997;26:667–674.PubMedCrossRef Huch K, Kuettner KE, Dieppe P. Osteoarthritis in ankle and knee joints. Semin Arthritis Rheum. 1997;26:667–674.PubMedCrossRef
13.
Zurück zum Zitat Ihn JC, Kim SJ, Park IH. In vitro study of contact area and pressure distribution in the human knee after partial and total meniscectomy. Int Orthop. 1993;17:214–218.PubMedCrossRef Ihn JC, Kim SJ, Park IH. In vitro study of contact area and pressure distribution in the human knee after partial and total meniscectomy. Int Orthop. 1993;17:214–218.PubMedCrossRef
14.
Zurück zum Zitat Jaakkola JI, Mann RA. A review of rheumatoid arthritis affecting the foot and ankle. Foot Ankle Int. 2004;25:866–874.PubMed Jaakkola JI, Mann RA. A review of rheumatoid arthritis affecting the foot and ankle. Foot Ankle Int. 2004;25:866–874.PubMed
15.
Zurück zum Zitat Kang Y, Koepp H, Cole AA, Kuettner KE, Homandberg GA. Cultured human ankle and knee cartilage differ in susceptibility to damage mediated by fibronectin fragments. J Orthop Res. 1998;16:551–556.PubMedCrossRef Kang Y, Koepp H, Cole AA, Kuettner KE, Homandberg GA. Cultured human ankle and knee cartilage differ in susceptibility to damage mediated by fibronectin fragments. J Orthop Res. 1998;16:551–556.PubMedCrossRef
16.
Zurück zum Zitat Kimizuka M, Kurosawa H, Fukubayashi T. Load-bearing pattern of the ankle joint: contact area and pressure distribution. Arch Orthop Trauma Surg. 1980;96:45–49.PubMedCrossRef Kimizuka M, Kurosawa H, Fukubayashi T. Load-bearing pattern of the ankle joint: contact area and pressure distribution. Arch Orthop Trauma Surg. 1980;96:45–49.PubMedCrossRef
17.
Zurück zum Zitat Kitaoka HB, Alexander IJ, Adelaar RS, Nunley JA, Myerson MS, Sanders M. Clinical rating systems for the ankle-hindfoot, midfoot, hallux, and lesser toes. Foot Ankle Int. 1994;15:349–353.PubMed Kitaoka HB, Alexander IJ, Adelaar RS, Nunley JA, Myerson MS, Sanders M. Clinical rating systems for the ankle-hindfoot, midfoot, hallux, and lesser toes. Foot Ankle Int. 1994;15:349–353.PubMed
18.
Zurück zum Zitat Knupp M, Ledermann H, Magerkurth O, Hinterman B. The surgical tibiotalar angle: a radiologic study. Foot Ankle Int. 2005;26:713–716.PubMed Knupp M, Ledermann H, Magerkurth O, Hinterman B. The surgical tibiotalar angle: a radiologic study. Foot Ankle Int. 2005;26:713–716.PubMed
19.
Zurück zum Zitat Koralewicz LM, Engh GA. Comparison of proprioception in arthritic and age-matched normal knees. J Bone Joint Surg Am. 2000;82:1582–1588.PubMed Koralewicz LM, Engh GA. Comparison of proprioception in arthritic and age-matched normal knees. J Bone Joint Surg Am. 2000;82:1582–1588.PubMed
20.
Zurück zum Zitat Lindsjö U. Operative treatment of ankle fracture-dislocations: a follow-up study of 306/321 consecutive cases. Clin Orthop Relat Res. 1985;199:28–38.PubMed Lindsjö U. Operative treatment of ankle fracture-dislocations: a follow-up study of 306/321 consecutive cases. Clin Orthop Relat Res. 1985;199:28–38.PubMed
21.
Zurück zum Zitat Lofvenberg R, Karrholm J, Lund B. The outcome of nonoperated patients with chronic lateral instability of the ankle: a 20-year follow-up study. Foot Ankle Int. 1994;15:165–169.PubMed Lofvenberg R, Karrholm J, Lund B. The outcome of nonoperated patients with chronic lateral instability of the ankle: a 20-year follow-up study. Foot Ankle Int. 1994;15:165–169.PubMed
22.
Zurück zum Zitat Marsh JL, Buckwalter J, Gelberman R, Dirschl D, Olson S, Brown T, Llinias A. Articular fractures: does an anatomic reduction really change the result? J Bone Joint Surg Am. 2002;84:1259–1271.PubMed Marsh JL, Buckwalter J, Gelberman R, Dirschl D, Olson S, Brown T, Llinias A. Articular fractures: does an anatomic reduction really change the result? J Bone Joint Surg Am. 2002;84:1259–1271.PubMed
23.
Zurück zum Zitat Martin JA, Ellerbroek SM, Buckwalter JA. Age-related decline in chondrocyte response to insulin-like growth factor: I. The role of growth factor binding proteins. J Orthop Res. 1997;15:491–498.PubMedCrossRef Martin JA, Ellerbroek SM, Buckwalter JA. Age-related decline in chondrocyte response to insulin-like growth factor: I. The role of growth factor binding proteins. J Orthop Res. 1997;15:491–498.PubMedCrossRef
24.
Zurück zum Zitat Melton LJ III, Khosla S, Crowson CS, O’Connor MK, O’Fallon WM, Riggs BL. Epidemiology of sarcopenia. J Am Geriatr Soc. 2000;48:625–630.PubMed Melton LJ III, Khosla S, Crowson CS, O’Connor MK, O’Fallon WM, Riggs BL. Epidemiology of sarcopenia. J Am Geriatr Soc. 2000;48:625–630.PubMed
25.
Zurück zum Zitat Monroe MT, Beals TC, Manoli A. Clinical outcome of arthrodesis of the ankle using rigid internal fixation with cancellous screws. Foot Ankle Int. 1999;20:227–231.PubMed Monroe MT, Beals TC, Manoli A. Clinical outcome of arthrodesis of the ankle using rigid internal fixation with cancellous screws. Foot Ankle Int. 1999;20:227–231.PubMed
26.
Zurück zum Zitat Mont MA, Sedlin ED, Weiner LS, Miller AR. Postoperative radiographs as predictors of clinical outcome in unstable ankle fractures. J Orthop Trauma. 1992;6:352–357.PubMedCrossRef Mont MA, Sedlin ED, Weiner LS, Miller AR. Postoperative radiographs as predictors of clinical outcome in unstable ankle fractures. J Orthop Trauma. 1992;6:352–357.PubMedCrossRef
27.
Zurück zum Zitat Morrey BF, Wiedeman GP Jr. Complications and long-term results of ankle arthrodeses following trauma. J Bone Joint Surg Am. 1980;62:777–784.PubMed Morrey BF, Wiedeman GP Jr. Complications and long-term results of ankle arthrodeses following trauma. J Bone Joint Surg Am. 1980;62:777–784.PubMed
28.
Zurück zum Zitat Okuda R, Kinoshita M, Morikawa J, Yasuda T, Abe M. Arthroscopic findings in chronic lateral ankle instability: do focal chondral lesions influence the results of ligament reconstruction? Am J Sports Med. 2005;33:35–42.PubMedCrossRef Okuda R, Kinoshita M, Morikawa J, Yasuda T, Abe M. Arthroscopic findings in chronic lateral ankle instability: do focal chondral lesions influence the results of ligament reconstruction? Am J Sports Med. 2005;33:35–42.PubMedCrossRef
29.
Zurück zum Zitat Peyron JG. The epidemiology of osteoarthritis. In: Moskowitz RW, Howell DS, Goldberg VM, Mankin HJ, eds. Osteoarthritis. Diagnosis and Treatment. Philadelphia, PA: WB Saunders; 1984:9–27. Peyron JG. The epidemiology of osteoarthritis. In: Moskowitz RW, Howell DS, Goldberg VM, Mankin HJ, eds. Osteoarthritis. Diagnosis and Treatment. Philadelphia, PA: WB Saunders; 1984:9–27.
30.
Zurück zum Zitat Phillips WA, Schwartz HS, Keller CS, Woodward HR, Rudd WS, Spiegel PG, Laros GS. A prospective, randomized study of the management of severe ankle fractures. J Bone Joint Surg Am. 1985;67:67–78.PubMed Phillips WA, Schwartz HS, Keller CS, Woodward HR, Rudd WS, Spiegel PG, Laros GS. A prospective, randomized study of the management of severe ankle fractures. J Bone Joint Surg Am. 1985;67:67–78.PubMed
31.
Zurück zum Zitat Puno RM, Vaughan JJ, Stetten ML, Johnson JR. Long-term effects of tibial angular malunion on the knee and ankle joints. J Orthop Trauma. 1991;5:247–254.PubMedCrossRef Puno RM, Vaughan JJ, Stetten ML, Johnson JR. Long-term effects of tibial angular malunion on the knee and ankle joints. J Orthop Trauma. 1991;5:247–254.PubMedCrossRef
32.
Zurück zum Zitat Ruedi T. Fractures of the lower end of the tibia into the ankle joint: results 9 years after open reduction and internal fixation. Injury. 1973;5:130–134.PubMedCrossRef Ruedi T. Fractures of the lower end of the tibia into the ankle joint: results 9 years after open reduction and internal fixation. Injury. 1973;5:130–134.PubMedCrossRef
33.
Zurück zum Zitat Saltzman CL, Salamon ML, Blanchard GM, Huff T, Hayes A, Buckwalter JA, Amendola A. Epidemiology of ankle arthritis: report of a consecutive series of 639 patients from a tertiary orthopaedic center. Iowa Orthop J. 2005;25:44–46.PubMed Saltzman CL, Salamon ML, Blanchard GM, Huff T, Hayes A, Buckwalter JA, Amendola A. Epidemiology of ankle arthritis: report of a consecutive series of 639 patients from a tertiary orthopaedic center. Iowa Orthop J. 2005;25:44–46.PubMed
34.
Zurück zum Zitat Seitz WH, Andrews DL, Shelton ML, Feldman F. Triplane fractures of the adolescent ankle: a report of three cases. Injury. 1985;16:547–553.PubMedCrossRef Seitz WH, Andrews DL, Shelton ML, Feldman F. Triplane fractures of the adolescent ankle: a report of three cases. Injury. 1985;16:547–553.PubMedCrossRef
35.
Zurück zum Zitat Shepherd DE, Seedhom BB. Thickness of human articular cartilage in joints of the lower limb. Ann Rheum Dis. 1999;58:27–34.PubMedCrossRef Shepherd DE, Seedhom BB. Thickness of human articular cartilage in joints of the lower limb. Ann Rheum Dis. 1999;58:27–34.PubMedCrossRef
36.
Zurück zum Zitat Stamatis ED, Cooper PS, Myerson MS. Supramalleolar osteotomy for the treatment of distal tibial angular deformities and arthritis of the ankle joint. Foot Ankle Int. 2003;24:754–764.PubMed Stamatis ED, Cooper PS, Myerson MS. Supramalleolar osteotomy for the treatment of distal tibial angular deformities and arthritis of the ankle joint. Foot Ankle Int. 2003;24:754–764.PubMed
37.
Zurück zum Zitat Stauffer RN, Chao EY, Brewster RC. Force and motion analysis of the normal, diseased, and prosthetic ankle joint. Clin Orthop Relat Res. 1977;127:189–196.PubMed Stauffer RN, Chao EY, Brewster RC. Force and motion analysis of the normal, diseased, and prosthetic ankle joint. Clin Orthop Relat Res. 1977;127:189–196.PubMed
38.
Zurück zum Zitat Taga I, Shino K, Inoue M, Nakata K, Maeda A. Articular cartilage lesions in ankles with lateral ligament injury: an arthroscopic study. Am J Sports Med. 1993;21:120–126.PubMedCrossRef Taga I, Shino K, Inoue M, Nakata K, Maeda A. Articular cartilage lesions in ankles with lateral ligament injury: an arthroscopic study. Am J Sports Med. 1993;21:120–126.PubMedCrossRef
39.
Zurück zum Zitat Takakura Y, Takaoka T, Tanaka Y, Yajima H, Tamai S. Results of opening-wedge osteotomy for the treatment of a post-traumatic varus deformity of the ankle. J Bone Joint Surg Am. 1998;80:213–218.PubMedCrossRef Takakura Y, Takaoka T, Tanaka Y, Yajima H, Tamai S. Results of opening-wedge osteotomy for the treatment of a post-traumatic varus deformity of the ankle. J Bone Joint Surg Am. 1998;80:213–218.PubMedCrossRef
40.
Zurück zum Zitat Thomas RH, Daniels TR. Current concepts review: ankle arthritis. J Bone Joint Surg Am. 2003;85:923–936.PubMed Thomas RH, Daniels TR. Current concepts review: ankle arthritis. J Bone Joint Surg Am. 2003;85:923–936.PubMed
41.
Zurück zum Zitat Treppo S, Koepp H, Quan EC, Cole AA, Kuettner KE, Grodzinsky AJ. Comparison of biomechanical and biochemical properties of cartilage from human knee and ankle pairs. J Orthop Res. 2000;18:739–748.PubMedCrossRef Treppo S, Koepp H, Quan EC, Cole AA, Kuettner KE, Grodzinsky AJ. Comparison of biomechanical and biochemical properties of cartilage from human knee and ankle pairs. J Orthop Res. 2000;18:739–748.PubMedCrossRef
42.
Zurück zum Zitat Wyrsch B, McFerran MA, McAndrew M, Limbird TJ, Harper MC, Johnson KD, Schwartz HS. Operative treatment of fractures of the tibial plafond: a randomized, prospective study. J Bone Joint Surg Am. 1996;78:1646–1657.PubMed Wyrsch B, McFerran MA, McAndrew M, Limbird TJ, Harper MC, Johnson KD, Schwartz HS. Operative treatment of fractures of the tibial plafond: a randomized, prospective study. J Bone Joint Surg Am. 1996;78:1646–1657.PubMed
43.
Zurück zum Zitat Wyss C, Zollinger H. The causes of subsequent arthrodesis of the ankle joint. Acta Orthop Belg. 1991;57(suppl 1):22–27.PubMed Wyss C, Zollinger H. The causes of subsequent arthrodesis of the ankle joint. Acta Orthop Belg. 1991;57(suppl 1):22–27.PubMed
Metadaten
Titel
Etiology of Ankle Osteoarthritis
verfasst von
Victor Valderrabano, MD, PhD
Monika Horisberger, MD
Iain Russell, MD
Hugh Dougall, MD
Beat Hintermann, MD
Publikationsdatum
01.07.2009
Verlag
Springer-Verlag
Erschienen in
Clinical Orthopaedics and Related Research® / Ausgabe 7/2009
Print ISSN: 0009-921X
Elektronische ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-008-0543-6

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