Skip to main content
Erschienen in: Heart Failure Reviews 1/2008

01.02.2008

Exercise training in patients with heart failure: clinical outcomes, safety, and indications

verfasst von: Robert S. McKelvie

Erschienen in: Heart Failure Reviews | Ausgabe 1/2008

Einloggen, um Zugang zu erhalten

Abstract

Heart failure (HF) patients are often counseled to limit their physical activity, however, this advice may not be appropriate. Data has accumulated supporting the effectiveness of exercise training to improve fitness levels and symptoms. There are also data suggesting that training may reduce mortality and morbidity in HF patients. Studies have demonstrated that exercise training can be performed safely in appropriately evaluated HF patients. The literature would support the prescribing of exercise training to NYHA II–III HF patients. Consideration could also be given to training stable NYHA IV HF patients who are not symptomatic at rest. This article reviews the effects of exercise training on clinical outcomes and addressing the safety of exercise training and the indications for training in HF patients.
Literatur
1.
Zurück zum Zitat McKelvie RS, McCartney N, Teo KK, Humen D, Montague T, Yusuf S (1995) Effects of exercise training in patients with congestive heart failure: a critical Review. J Am Coll Cardiol 25:789–796PubMedCrossRef McKelvie RS, McCartney N, Teo KK, Humen D, Montague T, Yusuf S (1995) Effects of exercise training in patients with congestive heart failure: a critical Review. J Am Coll Cardiol 25:789–796PubMedCrossRef
2.
Zurück zum Zitat Pina IL, Apstein CS, Balady GJ et al (2003) A statement from the American Heart Association Committee on exercise, rehabilitation, and prevention. Circulation 107:1210–1225PubMedCrossRef Pina IL, Apstein CS, Balady GJ et al (2003) A statement from the American Heart Association Committee on exercise, rehabilitation, and prevention. Circulation 107:1210–1225PubMedCrossRef
3.
Zurück zum Zitat Piepoli M, Clark AL, Volterrani M, Adamopoulos S, Sleight P, Coats A (1996) Contribution of muscle afferents to the hemodynamic, autonomic, and ventilatory responses to exercise in patients with chronic heart failure. Effects of physical training. Circulation 93:940–952PubMed Piepoli M, Clark AL, Volterrani M, Adamopoulos S, Sleight P, Coats A (1996) Contribution of muscle afferents to the hemodynamic, autonomic, and ventilatory responses to exercise in patients with chronic heart failure. Effects of physical training. Circulation 93:940–952PubMed
4.
Zurück zum Zitat Ponikowski P, Chua TP, Francis DP, Capucci A, Coats AJ, Piepoli MF et al (2001) Muscle ergoreceptor overactivity reflects deterioration in clinical status and cardiorespiratory reflex control in chronic heart failure. Circulation 104:2324–2330PubMedCrossRef Ponikowski P, Chua TP, Francis DP, Capucci A, Coats AJ, Piepoli MF et al (2001) Muscle ergoreceptor overactivity reflects deterioration in clinical status and cardiorespiratory reflex control in chronic heart failure. Circulation 104:2324–2330PubMedCrossRef
5.
Zurück zum Zitat Scott A, Wensel R, Davos CH, Kemp M, Kaczmarek A, Hooper J et al (2002) Chemical mediators of the muscle ergoreflex in chronic heart failure: a putative role for prostaglandins in reflex ventilatory control. Circulation 106:214–220PubMedCrossRef Scott A, Wensel R, Davos CH, Kemp M, Kaczmarek A, Hooper J et al (2002) Chemical mediators of the muscle ergoreflex in chronic heart failure: a putative role for prostaglandins in reflex ventilatory control. Circulation 106:214–220PubMedCrossRef
6.
Zurück zum Zitat Belardinelli R, Georgiou D, Cianci G et al (1999) Randomized, controlled trial of long-term moderate exercise training in chronic heart failure. Effects on functional capacity, quality of life, and clinical outcome. Circulation 99:1173–1182PubMed Belardinelli R, Georgiou D, Cianci G et al (1999) Randomized, controlled trial of long-term moderate exercise training in chronic heart failure. Effects on functional capacity, quality of life, and clinical outcome. Circulation 99:1173–1182PubMed
7.
Zurück zum Zitat Lloyd-Williams F, Mair FS, Leitner M (2002) Exercise training and heart failure: a systematic review of current evidence. Br J Gen Pract 52:47–55PubMed Lloyd-Williams F, Mair FS, Leitner M (2002) Exercise training and heart failure: a systematic review of current evidence. Br J Gen Pract 52:47–55PubMed
8.
Zurück zum Zitat McKelvie RS, Teo KK, Roberts R, McCartney N, Humen D, Montague T et al (2002) Effects of exercise training in patients with heart failure: The Exercise Rehabilitation Trial (EXERT). Am Heart J 144:23–30PubMedCrossRef McKelvie RS, Teo KK, Roberts R, McCartney N, Humen D, Montague T et al (2002) Effects of exercise training in patients with heart failure: The Exercise Rehabilitation Trial (EXERT). Am Heart J 144:23–30PubMedCrossRef
9.
Zurück zum Zitat Smart N, Marwick TH (2004) Exercise training for patients with heart failure: a systematic review of factors that improve mortality and morbidity. Am J Med 116:693–706PubMedCrossRef Smart N, Marwick TH (2004) Exercise training for patients with heart failure: a systematic review of factors that improve mortality and morbidity. Am J Med 116:693–706PubMedCrossRef
10.
Zurück zum Zitat Piepoli MF, Davos C, Francis DP, Coats AJS (2004) Exercise training meta-analysis of trials in patients with chronic heart failure (ExTraMATCH). BMJ 328:189–191PubMedCrossRef Piepoli MF, Davos C, Francis DP, Coats AJS (2004) Exercise training meta-analysis of trials in patients with chronic heart failure (ExTraMATCH). BMJ 328:189–191PubMedCrossRef
11.
Zurück zum Zitat Gianuzzi P, Tavazzi L, Meyer K, Drexler H, Dubach P, Meyers J et al (2001) Recommendations for exercising training in chronic heart failure patients. Eur Heart J 22:125–135CrossRef Gianuzzi P, Tavazzi L, Meyer K, Drexler H, Dubach P, Meyers J et al (2001) Recommendations for exercising training in chronic heart failure patients. Eur Heart J 22:125–135CrossRef
12.
Zurück zum Zitat Keteyian SJ, Levine AB, Brawner CA, Katacha T, Rogers FJ, Schairer JR et al (1996) Exercise training in patients with heart failure. A randomized controlled trial. Ann Int Med 124:1051–1057PubMed Keteyian SJ, Levine AB, Brawner CA, Katacha T, Rogers FJ, Schairer JR et al (1996) Exercise training in patients with heart failure. A randomized controlled trial. Ann Int Med 124:1051–1057PubMed
13.
Zurück zum Zitat Hambrecht R, Offner B, Schuler G, Niebauer J, Fiehn E, Kalberer B et al (1995) Physical training in patients with stable chronic heart failure: effects on cardiorespiratory fitness and ultrastructural abnormalities of leg muscles. J Am Coll Cardiol 25:1239–1249PubMedCrossRef Hambrecht R, Offner B, Schuler G, Niebauer J, Fiehn E, Kalberer B et al (1995) Physical training in patients with stable chronic heart failure: effects on cardiorespiratory fitness and ultrastructural abnormalities of leg muscles. J Am Coll Cardiol 25:1239–1249PubMedCrossRef
14.
Zurück zum Zitat Belardinelli R, Georgiou D, Scocco V, Barstow TJ, Purcaro A (1995) Low intensity exercise training in patients with chronic heart failure. J Am Coll Cardiol 26:975–982PubMedCrossRef Belardinelli R, Georgiou D, Scocco V, Barstow TJ, Purcaro A (1995) Low intensity exercise training in patients with chronic heart failure. J Am Coll Cardiol 26:975–982PubMedCrossRef
15.
Zurück zum Zitat Dubach P, Meyers J, Dziekan G, Goebbels U, Reinhart W, Moller P et al (1997) Effect of high intensity exercise training on central hemodynamic responses to exercise in man with reduced left ventricular function. J Am Coll Cardiol 29:1591–1598PubMedCrossRef Dubach P, Meyers J, Dziekan G, Goebbels U, Reinhart W, Moller P et al (1997) Effect of high intensity exercise training on central hemodynamic responses to exercise in man with reduced left ventricular function. J Am Coll Cardiol 29:1591–1598PubMedCrossRef
16.
Zurück zum Zitat Dubach P, Myers J, Dziekan G, Goebbels U, Reinhart W, Vogt P et al (1997) Effect of exercise training on myocardial remodeling in patients with reduced left ventricular function after myocardial infarction: application of magnetic resonance imaging. Circulation 95:2060–2067PubMed Dubach P, Myers J, Dziekan G, Goebbels U, Reinhart W, Vogt P et al (1997) Effect of exercise training on myocardial remodeling in patients with reduced left ventricular function after myocardial infarction: application of magnetic resonance imaging. Circulation 95:2060–2067PubMed
17.
Zurück zum Zitat Kiilavuory K, Sovijarvi A, Navery H, Ikonen T, Leinonen H (1996) Effect of physical training on exercise capacity and gas exchange in patients with chronic heart failure. Chest 110:985–991 Kiilavuory K, Sovijarvi A, Navery H, Ikonen T, Leinonen H (1996) Effect of physical training on exercise capacity and gas exchange in patients with chronic heart failure. Chest 110:985–991
18.
Zurück zum Zitat Belardinelli R, Georgiou D, Cianci G, Purcaro A (1996) Effects of exercise training on left ventricular filling at rest and during exercise in patients with ischemic cardiomyopathy and severe left ventricular systolic dysfunction. Am Heart J 132:61–70PubMedCrossRef Belardinelli R, Georgiou D, Cianci G, Purcaro A (1996) Effects of exercise training on left ventricular filling at rest and during exercise in patients with ischemic cardiomyopathy and severe left ventricular systolic dysfunction. Am Heart J 132:61–70PubMedCrossRef
19.
Zurück zum Zitat Sullivan MJ, Higginbotham MB, Cobb F (1988) Exercise training in patients with severe left ventricular dysfunction: hemodynamic and metabolic effects. Circulation 78:506–515PubMed Sullivan MJ, Higginbotham MB, Cobb F (1988) Exercise training in patients with severe left ventricular dysfunction: hemodynamic and metabolic effects. Circulation 78:506–515PubMed
20.
Zurück zum Zitat Hornig B, Maier V, Drexler H (1996) Physical training improves endothelial function in patients with chronic heart failure. Circulation 93:210–214PubMed Hornig B, Maier V, Drexler H (1996) Physical training improves endothelial function in patients with chronic heart failure. Circulation 93:210–214PubMed
21.
Zurück zum Zitat Hambrecht R, Fiehn E, Weigl C, Gielen S, Hamann C, Kaiser R et al (1998) Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure. Circulation 98:2709–2715PubMed Hambrecht R, Fiehn E, Weigl C, Gielen S, Hamann C, Kaiser R et al (1998) Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure. Circulation 98:2709–2715PubMed
22.
Zurück zum Zitat Katz A, Yuen J, Bijou R (1997) Training improves endothelium-dependent vasodilation in resistance vessels of patients with heart failure. J Appl Physiol 82:1488–1492PubMedCrossRef Katz A, Yuen J, Bijou R (1997) Training improves endothelium-dependent vasodilation in resistance vessels of patients with heart failure. J Appl Physiol 82:1488–1492PubMedCrossRef
23.
Zurück zum Zitat Hambrecht R, Adams V, Erbs S, Linke A, Krankel N, Shu Y et al (2003) Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase. Circulation 107:3152–3158PubMedCrossRef Hambrecht R, Adams V, Erbs S, Linke A, Krankel N, Shu Y et al (2003) Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase. Circulation 107:3152–3158PubMedCrossRef
24.
Zurück zum Zitat Fisher D, Rossa S, Landmesser U, Spiekermann S, Engberding N, Horning B et al (2005) Endothelial dysfunction in patients with chronic heart failure is independently associated with increased incidence of hospitalization, cardiac transplantation, or death. Eur Heart J 26:65–69CrossRef Fisher D, Rossa S, Landmesser U, Spiekermann S, Engberding N, Horning B et al (2005) Endothelial dysfunction in patients with chronic heart failure is independently associated with increased incidence of hospitalization, cardiac transplantation, or death. Eur Heart J 26:65–69CrossRef
25.
Zurück zum Zitat Katz S, Hryniewicz K, Hriljac I, Balidemaj K, Dimayuga C, Hudaihed A et al (2005) Vascular endothelial dysfunction and mortality risk in patients with chronic heart failure. Circulation 111(3):310–314PubMedCrossRef Katz S, Hryniewicz K, Hriljac I, Balidemaj K, Dimayuga C, Hudaihed A et al (2005) Vascular endothelial dysfunction and mortality risk in patients with chronic heart failure. Circulation 111(3):310–314PubMedCrossRef
26.
Zurück zum Zitat Minotti JR, Johnson EC, Hudson TL, Zuroske G, Murata G, Fukushina E et al (1990) Skeletal muscle response to exercise training in congestive heart failure. J Clin Invest 86:751–758PubMedCrossRef Minotti JR, Johnson EC, Hudson TL, Zuroske G, Murata G, Fukushina E et al (1990) Skeletal muscle response to exercise training in congestive heart failure. J Clin Invest 86:751–758PubMedCrossRef
27.
Zurück zum Zitat Hambrecht R, Fiehn E, Jiangtao Y, Niebauer J, Weigl C, Hilbrich L et al (1997) Effects of endurance training on mitochondrial ultra structure and fiber type distribution in skeletal muscle of patients with stable chronic heart failure. J Am Coll Cardiol 29:1067–1073PubMedCrossRef Hambrecht R, Fiehn E, Jiangtao Y, Niebauer J, Weigl C, Hilbrich L et al (1997) Effects of endurance training on mitochondrial ultra structure and fiber type distribution in skeletal muscle of patients with stable chronic heart failure. J Am Coll Cardiol 29:1067–1073PubMedCrossRef
28.
Zurück zum Zitat Coats AJS, Adamopoulos S, Radaelli A et al (1992) Controlled trial of physical training in chronic heart failure. Exercise performance, hemodynamics, ventilation, and autonomic function. Circulation 85:2119–2131PubMed Coats AJS, Adamopoulos S, Radaelli A et al (1992) Controlled trial of physical training in chronic heart failure. Exercise performance, hemodynamics, ventilation, and autonomic function. Circulation 85:2119–2131PubMed
29.
Zurück zum Zitat Kiilavuori K, Toivonen L, Naveri H et al (1995) Reversal of autonomic derangements by physical training in chronic heart failure assessed by heart rate variability. Eur Heart J 16:490–495PubMed Kiilavuori K, Toivonen L, Naveri H et al (1995) Reversal of autonomic derangements by physical training in chronic heart failure assessed by heart rate variability. Eur Heart J 16:490–495PubMed
30.
Zurück zum Zitat Roveda F, Middlekauff HR, Urbana M et al (2003) The effects of exercise training on sympathetic neural activation in advanced heart failure. J Am Coll Cardiol 42:854–860PubMedCrossRef Roveda F, Middlekauff HR, Urbana M et al (2003) The effects of exercise training on sympathetic neural activation in advanced heart failure. J Am Coll Cardiol 42:854–860PubMedCrossRef
31.
Zurück zum Zitat Conraads VM, Beckers P, Vaes J, Martin M, Van Hoof V, DeMaeyer C et al (2004) Combined endurance/resistance training reduces NT proBNP levels in patients with chronic heart failure. Eur Heart J 25:1797–1805PubMedCrossRef Conraads VM, Beckers P, Vaes J, Martin M, Van Hoof V, DeMaeyer C et al (2004) Combined endurance/resistance training reduces NT proBNP levels in patients with chronic heart failure. Eur Heart J 25:1797–1805PubMedCrossRef
32.
Zurück zum Zitat Levine B, Kalman J, Mayer L, Fillit HM, Packer M (1990) Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N Engl J Med 323:236–244PubMedCrossRef Levine B, Kalman J, Mayer L, Fillit HM, Packer M (1990) Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N Engl J Med 323:236–244PubMedCrossRef
33.
Zurück zum Zitat Adamopoulos S, Parissis J, Karatzas D, Kroupis C, Georgiadis M, Karavolias G et al (2002) Physical training modulates proinflammatory cytokines and the soluble Fas/soluble Faslingand system in patients with chronic heart failure. J Am Coll Cardiol 39:653–663PubMedCrossRef Adamopoulos S, Parissis J, Karatzas D, Kroupis C, Georgiadis M, Karavolias G et al (2002) Physical training modulates proinflammatory cytokines and the soluble Fas/soluble Faslingand system in patients with chronic heart failure. J Am Coll Cardiol 39:653–663PubMedCrossRef
34.
Zurück zum Zitat Whellan DJ, O’Connor CM, Lee KL et al (2007) Heart failure and a controlled trial investigating outcomes of exercise training (HF-ACTION): design and rationale. Am Heart J 153:201–211PubMedCrossRef Whellan DJ, O’Connor CM, Lee KL et al (2007) Heart failure and a controlled trial investigating outcomes of exercise training (HF-ACTION): design and rationale. Am Heart J 153:201–211PubMedCrossRef
35.
Zurück zum Zitat European Heart Failure Training Group (1998) Experience from controlled treats of physical training in chronic heart failure. Protocol and patient factors in effectiveness in the improvement in exercise tolerance. Eur Heart J 19:466–475CrossRef European Heart Failure Training Group (1998) Experience from controlled treats of physical training in chronic heart failure. Protocol and patient factors in effectiveness in the improvement in exercise tolerance. Eur Heart J 19:466–475CrossRef
36.
Zurück zum Zitat Van Tol BAF, Huijsmans RJ, Kroon DW et al (2006) Effects of exercise training on cardiac performance, exercise capacity and quality of life in patients with heart failure: a meta-analysis. Eur J Heart Fail 8:841–850PubMedCrossRef Van Tol BAF, Huijsmans RJ, Kroon DW et al (2006) Effects of exercise training on cardiac performance, exercise capacity and quality of life in patients with heart failure: a meta-analysis. Eur J Heart Fail 8:841–850PubMedCrossRef
37.
Zurück zum Zitat Parnell MM, Holst DP, Kaye DM (2002) Exercise training increases arterial compliance in patients with congestive heart failure. Clin Sci 102:1–7PubMedCrossRef Parnell MM, Holst DP, Kaye DM (2002) Exercise training increases arterial compliance in patients with congestive heart failure. Clin Sci 102:1–7PubMedCrossRef
38.
Zurück zum Zitat Tyni-Lenne R, Gordon A, Sylven C (1996) Improved quality of life in chronic heart failure patients following local endurance training with leg muscles. J Card Fail 2:111–117PubMedCrossRef Tyni-Lenne R, Gordon A, Sylven C (1996) Improved quality of life in chronic heart failure patients following local endurance training with leg muscles. J Card Fail 2:111–117PubMedCrossRef
39.
Zurück zum Zitat Giannuzzi P, Temporelli PL, Corra U et al (2003) Antiremodeling effect of long term exercise training in patients with stable chronic heart failure. Results of the ELVD-CHF Trial. Circulation 108:554–559PubMedCrossRef Giannuzzi P, Temporelli PL, Corra U et al (2003) Antiremodeling effect of long term exercise training in patients with stable chronic heart failure. Results of the ELVD-CHF Trial. Circulation 108:554–559PubMedCrossRef
40.
Zurück zum Zitat Koch M, Douard H, Broustet JP (1992) The benefit of graded physical exercise in chronic heart failure. Chest 101:231–235CrossRef Koch M, Douard H, Broustet JP (1992) The benefit of graded physical exercise in chronic heart failure. Chest 101:231–235CrossRef
41.
Zurück zum Zitat Oka RK, De Marco T, Haskell WL et al (2000) Impact of a home-based walking and resistance training program on quality of life in patients with heart failure. Am J Cardiol 85:365–369PubMedCrossRef Oka RK, De Marco T, Haskell WL et al (2000) Impact of a home-based walking and resistance training program on quality of life in patients with heart failure. Am J Cardiol 85:365–369PubMedCrossRef
42.
Zurück zum Zitat Wielenga RP, Erdman RAM, Huisveld IA et al (1998) Effect of exercise training on quality of life in patients with chronic heart failure. J Psychosom Res 45:459–464PubMedCrossRef Wielenga RP, Erdman RAM, Huisveld IA et al (1998) Effect of exercise training on quality of life in patients with chronic heart failure. J Psychosom Res 45:459–464PubMedCrossRef
43.
Zurück zum Zitat Koukouvou G, Kouidi E, Iacovides A et al (2004) Quality of life, psychological and physiological changes following exercise training in patients with chronic heart failure. J Rehabil Med 36:36–41PubMedCrossRef Koukouvou G, Kouidi E, Iacovides A et al (2004) Quality of life, psychological and physiological changes following exercise training in patients with chronic heart failure. J Rehabil Med 36:36–41PubMedCrossRef
44.
Zurück zum Zitat Keteyian SJ, Brawner CA, Schairer JR et al (1999) Effects of exercise training on chronotropic incompetence in patients with heart failure. Am heart J 138:233–240PubMedCrossRef Keteyian SJ, Brawner CA, Schairer JR et al (1999) Effects of exercise training on chronotropic incompetence in patients with heart failure. Am heart J 138:233–240PubMedCrossRef
45.
Zurück zum Zitat Quittan M, Sturm B, Wiesinger GF et al (1999) Quality of life in patients with chronic heart failure: a randomized controlled trial of changes induced by a regular exercise program. Scand J Rehabil Med 31:223–228PubMedCrossRef Quittan M, Sturm B, Wiesinger GF et al (1999) Quality of life in patients with chronic heart failure: a randomized controlled trial of changes induced by a regular exercise program. Scand J Rehabil Med 31:223–228PubMedCrossRef
46.
Zurück zum Zitat Owen A, Croucher L (2000) Effect of an exercise programme for elderly patients with heart failure. Eur J Heart Fail 2:65–70PubMedCrossRef Owen A, Croucher L (2000) Effect of an exercise programme for elderly patients with heart failure. Eur J Heart Fail 2:65–70PubMedCrossRef
47.
Zurück zum Zitat Hambrecht R, Gielen S, Linke A et al (2000) Effects of exercise training on left ventricular function and peripheral resistance in patients with chronic heart failure. A randomized trial. JAMA 283:3095–3101PubMedCrossRef Hambrecht R, Gielen S, Linke A et al (2000) Effects of exercise training on left ventricular function and peripheral resistance in patients with chronic heart failure. A randomized trial. JAMA 283:3095–3101PubMedCrossRef
48.
Zurück zum Zitat Fletcher GF, Balady GJ, Amsterdam EA et al (2001) Exercise standards for testing and training: a statement for healthcare professionals from the American Heart Association. Circulation 104:1694–1740PubMedCrossRef Fletcher GF, Balady GJ, Amsterdam EA et al (2001) Exercise standards for testing and training: a statement for healthcare professionals from the American Heart Association. Circulation 104:1694–1740PubMedCrossRef
49.
Zurück zum Zitat Haskell WL (1994) The efficacy and safety of exercise programs in cardiac rehabilitation. Med Sci Sports Exerc 26:815–823PubMed Haskell WL (1994) The efficacy and safety of exercise programs in cardiac rehabilitation. Med Sci Sports Exerc 26:815–823PubMed
50.
Zurück zum Zitat van Camp SP, Peterson RA (1986) Cardiovascular complications of outpatient cardiac rehabilitation programs. JAMA 256:1160–1163PubMedCrossRef van Camp SP, Peterson RA (1986) Cardiovascular complications of outpatient cardiac rehabilitation programs. JAMA 256:1160–1163PubMedCrossRef
51.
Zurück zum Zitat Vongvanich P, Paul-Labrador MJ, Merz CN (1996) Safety of medically supervised exercise in a cardiac rehabilitation centre. Am J Cardiol 77:1383–1385PubMedCrossRef Vongvanich P, Paul-Labrador MJ, Merz CN (1996) Safety of medically supervised exercise in a cardiac rehabilitation centre. Am J Cardiol 77:1383–1385PubMedCrossRef
52.
Zurück zum Zitat Mittleman MA, MaClure M, Tofler GH et al (1993) Triggering of acute myocardial infarction by heavy physical exertion. Protection against triggering by regular exertion. Determinants of Myocardial Infarction Onset Study Investigators. N Engl J Med 329:1677–1683PubMedCrossRef Mittleman MA, MaClure M, Tofler GH et al (1993) Triggering of acute myocardial infarction by heavy physical exertion. Protection against triggering by regular exertion. Determinants of Myocardial Infarction Onset Study Investigators. N Engl J Med 329:1677–1683PubMedCrossRef
53.
Zurück zum Zitat Willich SN, Lewis M, Lowel H et al (1993) Physical exertion as a trigger of acute myocardial infarction: Triggers and Mechanisms of Myocardial Infarction Study Group. N Engl J Med 329:1684–1690PubMedCrossRef Willich SN, Lewis M, Lowel H et al (1993) Physical exertion as a trigger of acute myocardial infarction: Triggers and Mechanisms of Myocardial Infarction Study Group. N Engl J Med 329:1684–1690PubMedCrossRef
54.
Zurück zum Zitat Burke AP, Farb A, Malcom GT et al (1999) Plaque rupture and sudden death related to exertion in men with coronary artery disease. JAMA 281:921–926PubMedCrossRef Burke AP, Farb A, Malcom GT et al (1999) Plaque rupture and sudden death related to exertion in men with coronary artery disease. JAMA 281:921–926PubMedCrossRef
55.
Zurück zum Zitat Berlin JA, Colditz GA (1990) A meta-analysis of physical activity in the prevention of coronary heart disease. Am J Epidemiol 132:612–628PubMed Berlin JA, Colditz GA (1990) A meta-analysis of physical activity in the prevention of coronary heart disease. Am J Epidemiol 132:612–628PubMed
56.
Zurück zum Zitat Oldridge NB, Guyatt GH, Fischer MS, Rimm AA (1988) Cardiac rehabilitation after myocardial infarction: combined experience of randomized clinical trials. JAMA 260:945–950PubMedCrossRef Oldridge NB, Guyatt GH, Fischer MS, Rimm AA (1988) Cardiac rehabilitation after myocardial infarction: combined experience of randomized clinical trials. JAMA 260:945–950PubMedCrossRef
57.
Zurück zum Zitat O’Connor GT, Buring JE, Yusuf S et al (1989) An overview of randomized trials of rehabilitation with exercise after myocardial infarction. Circulation 80:234–244PubMed O’Connor GT, Buring JE, Yusuf S et al (1989) An overview of randomized trials of rehabilitation with exercise after myocardial infarction. Circulation 80:234–244PubMed
58.
Zurück zum Zitat Lakka TA, Venalainen MD, Rauramaa R et al (1994) Relation of leisure-time physical activity and cardiorespiratory fitness to the risk of acute myocardial infarction in men. N Engl J Med 330:1549–1554PubMedCrossRef Lakka TA, Venalainen MD, Rauramaa R et al (1994) Relation of leisure-time physical activity and cardiorespiratory fitness to the risk of acute myocardial infarction in men. N Engl J Med 330:1549–1554PubMedCrossRef
59.
Zurück zum Zitat Tristani FE, Hughes CV, Archibald DG, Sheldahl LM, Cohn JN, Fletcher R (1987) Safety of graded symptom-limited exercise testing in patients with congestive heart failure. Circulation 76(Suppl 6):54–58 Tristani FE, Hughes CV, Archibald DG, Sheldahl LM, Cohn JN, Fletcher R (1987) Safety of graded symptom-limited exercise testing in patients with congestive heart failure. Circulation 76(Suppl 6):54–58
60.
Zurück zum Zitat Jugdutt BI, Michorowski BL, Kappagoda CT (1988) Exercise training after anterior Q wave myocardial infarction: importance of regional function and topography. J Am Coll Cardiol 12:362–372PubMedCrossRef Jugdutt BI, Michorowski BL, Kappagoda CT (1988) Exercise training after anterior Q wave myocardial infarction: importance of regional function and topography. J Am Coll Cardiol 12:362–372PubMedCrossRef
61.
Zurück zum Zitat Giannuzzi P, Tavazzi L, Temporelli PL, Corra U, Imparato A, Gattone M et al (1993) Long term physical training and left ventricular remodeling after anterior myocardial infarction: results of the Exercise in Anterior Myocardial Infarction (EAMI) Study Group. J Am Coll Cardiol 22:1821–1829PubMed Giannuzzi P, Tavazzi L, Temporelli PL, Corra U, Imparato A, Gattone M et al (1993) Long term physical training and left ventricular remodeling after anterior myocardial infarction: results of the Exercise in Anterior Myocardial Infarction (EAMI) Study Group. J Am Coll Cardiol 22:1821–1829PubMed
62.
Zurück zum Zitat Belardinelli R, Georgiou D, Cianci G, Purcaro A (1999) Randomized, controlled trial of long-term moderate exercise training in chronic heart failure. Effects on functional capacity, quality of life, and clinical outcome. Circulation 99:1173–1182PubMed Belardinelli R, Georgiou D, Cianci G, Purcaro A (1999) Randomized, controlled trial of long-term moderate exercise training in chronic heart failure. Effects on functional capacity, quality of life, and clinical outcome. Circulation 99:1173–1182PubMed
63.
Zurück zum Zitat Kobashigawa JA, Leaf DA, Lee N et al (1999) A controlled trial of exercise rehabilitation after heart transplantation. N Engl J Med 340:272–277PubMedCrossRef Kobashigawa JA, Leaf DA, Lee N et al (1999) A controlled trial of exercise rehabilitation after heart transplantation. N Engl J Med 340:272–277PubMedCrossRef
64.
Zurück zum Zitat Braith RW, Limarcher MC, Leggett SH et al (1993) Skeletal muscle strength in heart transplant recipients. J Heart Lung Transplant 12:1018–1023PubMed Braith RW, Limarcher MC, Leggett SH et al (1993) Skeletal muscle strength in heart transplant recipients. J Heart Lung Transplant 12:1018–1023PubMed
65.
Zurück zum Zitat Cahalin LP, Semigran MJ, Dec GW (1997) Inspiratory muscle training in patients with chronic heart failure awaiting cardiac transplatiation: results of a pilot clinical trial. Phys Ther 77:830–838PubMed Cahalin LP, Semigran MJ, Dec GW (1997) Inspiratory muscle training in patients with chronic heart failure awaiting cardiac transplatiation: results of a pilot clinical trial. Phys Ther 77:830–838PubMed
66.
Zurück zum Zitat Kavanagh T, Yacoub MH, Mertens DJ et al (1988) Cardiorespiratory responses to exercise training after orthopic cardiac transplantation. Circulation 77:162–171PubMed Kavanagh T, Yacoub MH, Mertens DJ et al (1988) Cardiorespiratory responses to exercise training after orthopic cardiac transplantation. Circulation 77:162–171PubMed
67.
Zurück zum Zitat Jaski BE, Kim J, Maly RS et al (1997) Effects of exercise during long-term support with a left ventricular assist device: results of the experience with left ventricular assist device with exercise (EVADE) pilot trial. Circulation 95:2401–2406PubMed Jaski BE, Kim J, Maly RS et al (1997) Effects of exercise during long-term support with a left ventricular assist device: results of the experience with left ventricular assist device with exercise (EVADE) pilot trial. Circulation 95:2401–2406PubMed
68.
Zurück zum Zitat Morrone TM, Buck LA, Catanese KA et al (1996) Early progressive mobilization of patients with left ventricular assist devices is safe and optimizes recover before heart transplantation. J Heart Lung Transplant 15:423–429PubMed Morrone TM, Buck LA, Catanese KA et al (1996) Early progressive mobilization of patients with left ventricular assist devices is safe and optimizes recover before heart transplantation. J Heart Lung Transplant 15:423–429PubMed
Metadaten
Titel
Exercise training in patients with heart failure: clinical outcomes, safety, and indications
verfasst von
Robert S. McKelvie
Publikationsdatum
01.02.2008
Verlag
Springer US
Erschienen in
Heart Failure Reviews / Ausgabe 1/2008
Print ISSN: 1382-4147
Elektronische ISSN: 1573-7322
DOI
https://doi.org/10.1007/s10741-007-9052-z

Weitere Artikel der Ausgabe 1/2008

Heart Failure Reviews 1/2008 Zur Ausgabe

Screening-Mammografie offenbart erhöhtes Herz-Kreislauf-Risiko

26.04.2024 Mammografie Nachrichten

Routinemäßige Mammografien helfen, Brustkrebs frühzeitig zu erkennen. Anhand der Röntgenuntersuchung lassen sich aber auch kardiovaskuläre Risikopatientinnen identifizieren. Als zuverlässiger Anhaltspunkt gilt die Verkalkung der Brustarterien.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Adipositas-Medikament auch gegen Schlafapnoe wirksam

24.04.2024 Adipositas Nachrichten

Der als Antidiabetikum sowie zum Gewichtsmanagement zugelassene Wirkstoff Tirzepatid hat in Studien bei adipösen Patienten auch schlafbezogene Atmungsstörungen deutlich reduziert, informiert der Hersteller in einer Vorab-Meldung zum Studienausgang.

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.