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Erschienen in: Journal of Nuclear Cardiology 6/2020

13.02.2019 | Editorial

Expanding the clinical potential of cardiac radionuclide adrenergic imaging

verfasst von: Mark I. Travin, MD, MASNC

Erschienen in: Journal of Nuclear Cardiology | Ausgabe 6/2020

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Excerpt

The autonomic nervous system, divided into sympathetic and parasympathetic components, plays an essential role in sustaining body functions. In particular, direct cardiac autonomic innervation working in conjunction with circulating neurohormones (epinephrine, norepinephrine (NE), renin-angiotensin-aldosterone system (RAAS) hormones, cytokines) controls cardiac function (heart rate, contractility) and adjusts vascular tone for maintenance of proper perfusion to organs and tissues.1
Literatur
1.
Zurück zum Zitat Triposkiadis F, Karayannis G, Giamouzis G, Skoularigis J, Louridas G, Butler J. The sympathetic nervous system in hear failure. Physiology, pathophysiology and clinical implications. J Am Coll Cardiol 2009;54:1747-62.CrossRef Triposkiadis F, Karayannis G, Giamouzis G, Skoularigis J, Louridas G, Butler J. The sympathetic nervous system in hear failure. Physiology, pathophysiology and clinical implications. J Am Coll Cardiol 2009;54:1747-62.CrossRef
2.
Zurück zum Zitat Esler M, Lambert G, Rocca BL, Vaddadi G, Kaye D. Sympathetic nerve activity and neurotransmitter release in humans: Translation from pathophysiology into clinical practice. Acta Physiol 2003;177:275-84.CrossRef Esler M, Lambert G, Rocca BL, Vaddadi G, Kaye D. Sympathetic nerve activity and neurotransmitter release in humans: Translation from pathophysiology into clinical practice. Acta Physiol 2003;177:275-84.CrossRef
3.
Zurück zum Zitat Vallbo AB, Hagbarth K, Wallin BG. Microneurography: how the technique developed and its role in the investigation of the sympathetic nervous system. J Appl Physiol 2004;96:1262-9.CrossRef Vallbo AB, Hagbarth K, Wallin BG. Microneurography: how the technique developed and its role in the investigation of the sympathetic nervous system. J Appl Physiol 2004;96:1262-9.CrossRef
4.
Zurück zum Zitat Travin MI. Cardiac autonomic imaging with SPECT tracers. J Nucl Cardiol 2013;20:128-43.CrossRef Travin MI. Cardiac autonomic imaging with SPECT tracers. J Nucl Cardiol 2013;20:128-43.CrossRef
5.
Zurück zum Zitat Thackeray JT, Bengel FM. Assessment of cardiac autonomic neuronal function using PET imaging. J Nucl Cardiol 2013;20:150-65.CrossRef Thackeray JT, Bengel FM. Assessment of cardiac autonomic neuronal function using PET imaging. J Nucl Cardiol 2013;20:150-65.CrossRef
6.
Zurück zum Zitat Jacobson AF, Senior R, Cerqueira MD, Wong ND, Thomas GS, Lopez VA, Agostini D, Weiland F, Chanda H, Narula J, on behalf of the ADMIRE_HF Investigators. Myocardial iodine-123 meta-iodobenzylguanidine imaging and cardiac events in heart failure. Results of the prospective ADMIRE-HF (AdreView Myocardial Imaging for Risk Evaluation in Heart Failure) study. J Am Coll Cardiol 2010;55:2212-21.CrossRef Jacobson AF, Senior R, Cerqueira MD, Wong ND, Thomas GS, Lopez VA, Agostini D, Weiland F, Chanda H, Narula J, on behalf of the ADMIRE_HF Investigators. Myocardial iodine-123 meta-iodobenzylguanidine imaging and cardiac events in heart failure. Results of the prospective ADMIRE-HF (AdreView Myocardial Imaging for Risk Evaluation in Heart Failure) study. J Am Coll Cardiol 2010;55:2212-21.CrossRef
8.
Zurück zum Zitat Schlaich MP, Krum H, Sobotka PA, Esler M. Renal denervation and hypertension. Am J Hypertens 2011;24:635-42.CrossRef Schlaich MP, Krum H, Sobotka PA, Esler M. Renal denervation and hypertension. Am J Hypertens 2011;24:635-42.CrossRef
10.
Zurück zum Zitat Krum H, Schlaich M, Whitbourne R, Sobotka PA, Sadowski J, Bartus K, Kapelak B, Walton A, Sievert H, Thambar S, Abraham WT, Esler M. Catheter-based renal sympathetic denervation for resistant hypertension: A multicenter safety and proof-of-principle cohort study. Lancet 2009;373:1275-81.CrossRef Krum H, Schlaich M, Whitbourne R, Sobotka PA, Sadowski J, Bartus K, Kapelak B, Walton A, Sievert H, Thambar S, Abraham WT, Esler M. Catheter-based renal sympathetic denervation for resistant hypertension: A multicenter safety and proof-of-principle cohort study. Lancet 2009;373:1275-81.CrossRef
11.
Zurück zum Zitat Mauri L, Kario K, Basile J, Daeman J, Davies J, Kirtane AJ, et al. A multinational clinical approach to assessing the effectiveness of catheter-based ultrasound renal denervation: The RADIANCE-HTN and REQUIRE clinical study designs. Am Heart J 2018;195:115-29.CrossRef Mauri L, Kario K, Basile J, Daeman J, Davies J, Kirtane AJ, et al. A multinational clinical approach to assessing the effectiveness of catheter-based ultrasound renal denervation: The RADIANCE-HTN and REQUIRE clinical study designs. Am Heart J 2018;195:115-29.CrossRef
12.
Zurück zum Zitat Hering D, Marusic P, Walton AS, Lambert EA, Krum H, Narkiewicz K, Lambert GW, Esler MD, Schlaich M. Sustained sympathetic and blood pressure reduction 1 year after renal denervation inpatients with resistant hypertension. Hypertension 2014;64:118-24.CrossRef Hering D, Marusic P, Walton AS, Lambert EA, Krum H, Narkiewicz K, Lambert GW, Esler MD, Schlaich M. Sustained sympathetic and blood pressure reduction 1 year after renal denervation inpatients with resistant hypertension. Hypertension 2014;64:118-24.CrossRef
13.
Zurück zum Zitat Brandt MC, Mahfoud F, Reda S, Schirmer SH, Erdmann E, Böhm M, Hoppe UC. Renal sympathetic denervation reduced left ventricular hypertrophy and improves cardiac function in patients with resistant hypertension. J Am Coll Cardiol 2012;59:901-9.CrossRef Brandt MC, Mahfoud F, Reda S, Schirmer SH, Erdmann E, Böhm M, Hoppe UC. Renal sympathetic denervation reduced left ventricular hypertrophy and improves cardiac function in patients with resistant hypertension. J Am Coll Cardiol 2012;59:901-9.CrossRef
14.
Zurück zum Zitat Fallavollita JA, Canty JM. Dysinnervated but viable myocardium in ischemic heart disease. J Nucl Cardiol 2010;17:1107-15.CrossRef Fallavollita JA, Canty JM. Dysinnervated but viable myocardium in ischemic heart disease. J Nucl Cardiol 2010;17:1107-15.CrossRef
15.
Zurück zum Zitat Bengel FM. Imaging targets of the sympathetic nervous system of the heart: translational considerations. J Nucl Med 2011;52:1167-70.CrossRef Bengel FM. Imaging targets of the sympathetic nervous system of the heart: translational considerations. J Nucl Med 2011;52:1167-70.CrossRef
16.
Zurück zum Zitat Schofer J, Spielmann R, Schuchert A, Weber K, Schlüter M. Iodine-123 meta-iodobenzylguanidine scintigraphy: A noninvasive method to demonstrate myocardial adrenergic nervous system disintegrity in patients idiopathic dilated cardiomyopathy. J Am Coll Cardiol 1988;12:1252-8.CrossRef Schofer J, Spielmann R, Schuchert A, Weber K, Schlüter M. Iodine-123 meta-iodobenzylguanidine scintigraphy: A noninvasive method to demonstrate myocardial adrenergic nervous system disintegrity in patients idiopathic dilated cardiomyopathy. J Am Coll Cardiol 1988;12:1252-8.CrossRef
17.
Zurück zum Zitat Tamaki S, Yamada T, Okuyama Y, Morita T, Sanada S, Tsukamoto Y, Masuda M, Okuda K, Iwasaki Y, Yasui T, Hori M, Fukunami M. Cardiac iodine-123 Metaiodobenzylguanidine imaging predicts sudden cardiac death independently of left ventricular ejection fraction in patients with chronic heart failure and left ventricular systolic dysfunction: Results from a comparative study with signal-averaged electrocardiogram, heart rate variability, and QT dispersion. J Am Coll Cardiol 2009;53:426-35.CrossRef Tamaki S, Yamada T, Okuyama Y, Morita T, Sanada S, Tsukamoto Y, Masuda M, Okuda K, Iwasaki Y, Yasui T, Hori M, Fukunami M. Cardiac iodine-123 Metaiodobenzylguanidine imaging predicts sudden cardiac death independently of left ventricular ejection fraction in patients with chronic heart failure and left ventricular systolic dysfunction: Results from a comparative study with signal-averaged electrocardiogram, heart rate variability, and QT dispersion. J Am Coll Cardiol 2009;53:426-35.CrossRef
18.
Zurück zum Zitat Donazzan L, Mahfoud F, Ewen S, Ukena C, Cremers B, Kirsch C, Hellwig D, Eweiwi T, Ezziddin S, Esler M, Böhm M. Effects of catheter-based renal denervation on cardiac sympathetic activity and innervation in patients with resistant hypertension. Clin Res Cardiol 2016;105:364-71.CrossRef Donazzan L, Mahfoud F, Ewen S, Ukena C, Cremers B, Kirsch C, Hellwig D, Eweiwi T, Ezziddin S, Esler M, Böhm M. Effects of catheter-based renal denervation on cardiac sympathetic activity and innervation in patients with resistant hypertension. Clin Res Cardiol 2016;105:364-71.CrossRef
19.
Zurück zum Zitat Inobe Y, Kugiyama K, Miyagi H, Ohgushi M, Tomiguchi S, Takahashi M, Yasue H. Long-lasting abnormalities in cardiac sympathetic nervous system in patients with coronary spastic angina: Quantitative analysis with iodine 123 metaiodobenzylguanidine myocardial scintigraphy. Am Heart J 1997;134:112-8.CrossRef Inobe Y, Kugiyama K, Miyagi H, Ohgushi M, Tomiguchi S, Takahashi M, Yasue H. Long-lasting abnormalities in cardiac sympathetic nervous system in patients with coronary spastic angina: Quantitative analysis with iodine 123 metaiodobenzylguanidine myocardial scintigraphy. Am Heart J 1997;134:112-8.CrossRef
20.
Zurück zum Zitat Watanabe K, Takahashi T, Miyajima S, Hirokawa Y, Tanabe N, Kato K, Kodama M, Aizawa Y, Tazawa S, Inoue M. Myocardial sympathetic denervation, fatty acid metabolism, and left ventricular wall motion in vasospastic angina. J Nucl Med 2002;43:1476-81.PubMed Watanabe K, Takahashi T, Miyajima S, Hirokawa Y, Tanabe N, Kato K, Kodama M, Aizawa Y, Tazawa S, Inoue M. Myocardial sympathetic denervation, fatty acid metabolism, and left ventricular wall motion in vasospastic angina. J Nucl Med 2002;43:1476-81.PubMed
21.
Zurück zum Zitat Sakata K, Shirotani M, Yoshida H, Kurata C. Iodine-123 metaiodobenzylguanidine cardiac imaging to identify and localize vasospastic angina without significant coronary artery narrowing. J Am Coll Cardiol 1997;30:370-6.CrossRef Sakata K, Shirotani M, Yoshida H, Kurata C. Iodine-123 metaiodobenzylguanidine cardiac imaging to identify and localize vasospastic angina without significant coronary artery narrowing. J Am Coll Cardiol 1997;30:370-6.CrossRef
22.
Zurück zum Zitat Sakata K, Yoshida H, Hoshino T, Kurata C. Sympathetic nerve activity in the spasm-induced coronary artery region associated with disease activity of vasospastic angina. J Am Coll Cardiol 1996;28:460-4.CrossRef Sakata K, Yoshida H, Hoshino T, Kurata C. Sympathetic nerve activity in the spasm-induced coronary artery region associated with disease activity of vasospastic angina. J Am Coll Cardiol 1996;28:460-4.CrossRef
23.
Zurück zum Zitat Taki J, Yasuhara S, Takamatsu T, Nakajima K, Tatami R, Ishise S, et al. Value of iodine-123 metaiodobenzylguanidine scintigraphy in patients with vasospastic angina. Eur J Nucl Med 1998;25:229-34.CrossRef Taki J, Yasuhara S, Takamatsu T, Nakajima K, Tatami R, Ishise S, et al. Value of iodine-123 metaiodobenzylguanidine scintigraphy in patients with vasospastic angina. Eur J Nucl Med 1998;25:229-34.CrossRef
24.
Zurück zum Zitat Feyz L, Henneman M, Verzijlbergen F, Kardys I, van Mieghem N, Daemen J. Renal sympathetic denervation in patients with vasospastic angina. J Nucl Cardiol 2019. Feyz L, Henneman M, Verzijlbergen F, Kardys I, van Mieghem N, Daemen J. Renal sympathetic denervation in patients with vasospastic angina. J Nucl Cardiol 2019.
25.
Zurück zum Zitat Feyz L, Wijchers S, Daemen J. Renal denervation as a treatment strategy for vasospastic angina induced ventricular tachycardia. Neth Heart J 2017;25:596-7.CrossRef Feyz L, Wijchers S, Daemen J. Renal denervation as a treatment strategy for vasospastic angina induced ventricular tachycardia. Neth Heart J 2017;25:596-7.CrossRef
Metadaten
Titel
Expanding the clinical potential of cardiac radionuclide adrenergic imaging
verfasst von
Mark I. Travin, MD, MASNC
Publikationsdatum
13.02.2019
Verlag
Springer International Publishing
Erschienen in
Journal of Nuclear Cardiology / Ausgabe 6/2020
Print ISSN: 1071-3581
Elektronische ISSN: 1532-6551
DOI
https://doi.org/10.1007/s12350-019-01629-8

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