Background
Methods
Data extraction
Data analysis
Results
Patient characteristics
Tumour classification (ICD9-CM) | % of patients |
---|---|
Malignant neuroendocrine tumours (Well- differentiated), (low grade NET) (carcinoid), (intermediate grade NET) (atypical carcinoid), (high grade NET) (atypical carcinoid). | 46.86 |
209.0 Small intestine | 6.95 |
209.1 Appendix, large intestine, and rectum | 5.05 |
209.2 Other and unspecified sites | 34.86 |
209.20 Unknown primary site | 2.46 |
209.21 Bronchus and lung | 17.34 |
209.22 Thymus | 0.14 |
209.23 Stomach | 3.15 |
209.24 Kidney | 0.27 |
209.25 Foregut, not otherwise specified | 0.60 |
209.26 Midgut, not otherwise specified | 2.15 |
209.27 Hindgut, not otherwise specified | 0.29 |
209.29 Other sites not elsewhere classified | 8.46 |
209.3 Malignant poorly differentiated neuroendocrine carcinomas (High grade NEC not otherwise specified), (small cell lung carcinoma), (small cell uterine carcinoma), (small cell neuroendocrine carcinoma), (large cell neuroendocrine carcinoma), (Merkel cell carcinoma). | 32.02 |
209.30 Malignant poorly differentiated NEC, any site | 28.16 |
209.31 Merkel carcinoma of the face | 1.03 |
209.32 Merkel carcinoma of the scalp and neck | 0.31 |
209.33 Merkel carcinoma of the upper limb | 0.56 |
209.34 Merkel carcinoma of the lower limb | 0.68 |
209.35 Merkel carcinoma of the trunk | 0.29 |
209.36 Merkel carcinoma of the buttock, genitals and others not elsewhere classified | 1.00 |
Benign neuroendocrine tumours (Well- differentiated, (low grade NET) (carcinoid), (intermediate grade NET) (atypical carcinoid). | 18.59 |
209.4 Small intestine | 1.23 |
209.5 Appendix, large intestine, and rectum | 2.08 |
209.6 Other and unspecified sites | 15.27 |
209.60 Unknown primary site | 2.37 |
209.61 Bronchus and lung | 6.25 |
209.62 Thymus | 0.04 |
209.63 Stomach | 1.74 |
209.64 Kidney | 0.07 |
209.65 Foregut, not otherwise specified | 0.33 |
209.66 Midgut, not otherwise specified | 1.07 |
209.67 Hindgut, not otherwise specified | 0.60 |
209.69 Other sites not elsewhere classified | 2.80 |
209.7 Secondary or metastatic neuroendocrine tumours | 42.93 |
209.70 Unspecified site | 0.32 |
209.71 Distant lymph nodes | 10.32 |
209.72 Liver | 14.69 |
209.73 Bone | 4.40 |
209.74 Perineum | 3.10 |
209.75 Secondary Merkel cell carcinoma | 0.93 |
209.79 Other sites not elsewhere classified | 9.17 |
Disease comorbidities | % of patients |
---|---|
Unspecified essential hypertension | 41.62 |
Liver metastases | 29.42 |
Diabetes mellitus (type I or II) | 18.38 |
Unspecified hyperlipidaemia | 18.33 |
Lymph nodes metastases | 18.23 |
Respiratory failure and chronic airway obstruction | 10.90 |
Bone metastases | 10.69 |
Renal failure and chronic kidney disease | 9.85 |
Anaemia | 9.22 |
Gastrointestinal secondary neoplasm | 8.97 |
Atrial fibrillation | 6.92 |
Pure hypercholesterolemia | 6.33 |
Diaphragmatic hernia | 6.30 |
Neoplasm related pain | 5.48 |
Obesity | 5.37 |
Healthcare usage and disease management
Total number | % of admissions | |
---|---|---|
Diagnostic procedures | ||
Tomography of abdomen or thorax | 4979 | 42.79 |
Biopsy | 3521 | 30.26 |
Radiography of abdomen or thorax | 2212 | 19.01 |
Echography of abdomen or digestive system | 1615 | 13.88 |
Magnetic resonance imaging (MRI) | 695 | 5.97 |
Surgery | ||
Total or partial pancreatectomy | 745 | 6.40 |
Partial resection of the intestine | 498 | 4.28 |
Total or partial cholecystectomy | 426 | 3.66 |
Total or partial splenectomy | 338 | 2.90 |
Partial hepatectomy | 134 | 1.15 |
Treatment | ||
Injection of other therapeutic substance | 1327 | 11.40 |
Chemotherapy | 797 | 6.85 |
Radiotherapy | 294 | 2.53 |
Others | ||
Antibiotic injection | 992 | 8.52 |
Palliative care | 511 | 4.39 |
Steroid injection | 364 | 3.13 |
Anticoagulant injection | 308 | 2.65 |
Blood transfusion | 182 | 1.56 |
Direct medical cost
Concept | Annual cost |
---|---|
Total expenses | €15,373,961 |
Per patient | €1686 |
Surgery | |
Major pancreatic surgery | €2,985,369 |
Major intestine surgery | €885,885 |
Cholecystectomy | €874,288 |
Major hepatic surgery | €536,966 |
Splenectomy | €424,434 |
Treatment administration | |
Chemotherapy | €361,115 |
Radiotherapy | €168,855 |