Erschienen in:
15.01.2020 | Case Report
Extraluminal Duodenal Gangliocytic Paraganglioma Presenting with Intractable Back Pain in a Patient with End-Stage Renal Disease
verfasst von:
Maxwell Kilcoyne, Gabrielle Gauvin, Jennifer Cooley, Rajeswari Nagarathinam, Max Lefton, Alexander Kutikov, Sanjay Reddy
Erschienen in:
Journal of Gastrointestinal Cancer
|
Ausgabe 2/2020
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Excerpt
Gangliocytic paragangliomas (GP) are rare neuroendocrine tumors (NET) defined by their triphasic histological features containing epithelioid, spindle, and ganglion-like cells [
1]. While GPs are nonfunctional benign NETs with a favorable prognosis [
2], preoperative diagnosis and surgical planning remain challenging as they are often misdiagnosed for other more aggressive NETs [
3]. GPs are most commonly located in the 2nd portion of the duodenum, although there are reports of GPs found in the respiratory system, spinal cord, esophagus, pancreas, and appendix [
1,
2]. GPs arising in the gastrointestinal tract are typically seen on endoscopy extending intraluminally. To our knowledge, this is the first case report of a large GP originating from the duodenum but completely invisible on endoscopy and extending into the retroperitoneum. …
