Introduction
Materials and methods
Results
Parents age | PMR/GCA (N = 179) | Controls (N = 253) | OR | 95%CI | p | |
---|---|---|---|---|---|---|
Mothers | < 90 | 148 (82.68%) | 243 (96.05%) | |||
≥ 90 | 31 (17.32%) | 10 (3.95%) | 2.34 | 1.11–11.95 | < 0.0005 | |
Fathers | < 90 ≥ 90 | 161 (89.94%) 18 (10.06%) | 203 (80.24%) 50 (19.76%) | 0.45 | 0.24–0.83 | 0.0064 |
One of parents | < 90 ≥ 90 | 136 (75.98%) 43 (24.02%) | 193 (76.28%) 60 (23.72%) | 1.02 | 0.63–1.63 | 0.9412 |
Both parents | < 90 ≥ 90 | 173 (96.65%) 6 (3.35%) | 253 (100.00%) 0 (0%) | 8.77 | 2.26–405.10 | 0.003 |
Mothers of female patients | < 90 ≥ 90 | 105 (84%) 20 (16%) | 149 (97%) 4 (3%) | 7.1 | 2.27–29.19 | 0.0001 |
Mothers of male patients | < 90 ≥ 90 | 43 (80) 11 (20%) | 94 (94%) 6 (6%) | 4.01 | 1.25–13.97 | 0.0066 |
N | Correlation coefficient | p | ||
---|---|---|---|---|
Number of nonagenarians in mothers | GCA | 124 | − 0.19 | 0.0002 |
Isolated GCA (without concomitant PMR) | 50 | − 0,24 | 0.00002 | |
PMR | 129 | − 0.21 | 0.00003 | |
Isolated PMR (without concomitant GCA) | 55 | − 0.29 | < 0.000005 | |
Number of nonagenarians in fathers | GCA | 124 | 0.16 | 0.0016 |
Isolated GCA (without concomitant PMR) | 50 | 0.07 | 0.1975 | |
PMR | 129 | 0.13 | 0.0087 | |
Isolated PMR (without concomitant GCA) | 55 | 0.03 | 0.5830 |
Length of life ± SD (min–max) | |||||
---|---|---|---|---|---|
PMR/GCA (N = 179) | GCA (N = 124) | Isolated PMR (without concomitant GCA) (N = 55) | Controls (N = 253) | p | |
All parents | 74.6 ± 15.6 | 73.7 ± 15.6 | 74.6 ± 17.0 | 76.2 ± 11.3 | > 0.05 |
Fathers | 71.2 ± 15.9 | 70.1 ± 15.8 (30–100) | 73.8 ± 16.1 (30–96) | 79.8 ± 10.7 (38–99) | > 0.05 |
Mothers | 77.9 ± 14.5 | 77.3 ± 14.5 (29–99) | 79.2 ± 14.5 (30–97) | 72.5 ± 10.8 (40–96) | > 0.05 |