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09.10.2020 | Original Article

Fecal, oral, blood and skin virome of laboratory rabbits

verfasst von: Yuqing Xiao, Hao Wang, Lei Feng, Jiamin Pan, Zeyu Chen, Huiling Wang, Shixing Yang, Quan Shen, Xiaochun Wang, Tongling Shan, Wen Zhang

Erschienen in: Archives of Virology | Ausgabe 12/2020

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Abstract

Here, we investigated the fecal, oral, blood, and skin virome of 10 laboratory rabbits using a viral metagenomic method. In the oral samples, we detected a novel polyomavirus (RabPyV), and phylogenetic analysis based on the large T antigen, VP1 and VP2 regions indicated that the novel strain might have undergone a recombination event. Recombination analysis based on related genomes confirmed that RabPyV is a multiple recombinant between rodent-like and avian-like polyomaviruses. In fecal samples, three partial or complete genome sequences of viruses belonging to the families Picobirnaviridae, Parvoviridae, Microviridae and Coronaviridae were characterized, and phylogenetic trees were constructed based on the predicted amino acid sequences of viral proteins. This study increases the amount of genetic information on viruses present in laboratory rabbits.

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Titel: Fecal, oral, blood and skin virome of laboratory rabbits
verfasst von: Yuqing Xiao
Hao Wang
Lei Feng
Jiamin Pan
Zeyu Chen
Huiling Wang
Shixing Yang
Quan Shen
Xiaochun Wang
Tongling Shan
Wen Zhang
Publikationsdatum: 09.10.2020
Verlag: Springer Vienna
Erschienen in: Archives of Virology / Ausgabe 12/2020
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-020-04808-y

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