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Familial Cancer

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15.09.2021 | Short Communication

Fibroadenoma in vulval ectopic breast tissue in a patient with PTEN Hamartoma Tumour Syndrome

verfasst von: Hannah Dawson, Alannah Smrke, Peter M. Ellery, Nafisa Wilkinson, Adam N. Rosenthal, Terri P. McVeigh

Erschienen in: Familial Cancer | Ausgabe 3/2022

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Abstract

PTEN is a tumour suppressor gene involved in regulating cell division. Pathogenic germline variants in PTEN predispose to benign and malignant growths of numerous organs, including of the breast. In the following report, we describe the first documented case of a fibroadenoma developing in ectopic breast tissue of the vulva in a patient with a germline pathogenic variant in PTEN. This highlights the risk of hyperplasia developing in any breast tissue, including rare ectopic sites, particularly in patients with underlying germline variants in cancer susceptibility genes.

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Titel: Fibroadenoma in vulval ectopic breast tissue in a patient with PTEN Hamartoma Tumour Syndrome
verfasst von: Hannah Dawson
Alannah Smrke
Peter M. Ellery
Nafisa Wilkinson
Adam N. Rosenthal
Terri P. McVeigh
Publikationsdatum: 15.09.2021
Verlag: Springer Netherlands
Erschienen in: Familial Cancer / Ausgabe 3/2022
Print ISSN: 1389-9600
Elektronische ISSN: 1573-7292
DOI: https://doi.org/10.1007/s10689-021-00275-9

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25.04.2024 | Nierenkarzinom | Nachrichten

Springer Medizin

Fibroadenoma in vulval ectopic breast tissue in a patient with PTEN Hamartoma Tumour Syndrome

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