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Erschienen in: Cardiovascular Drugs and Therapy 5-6/2017

30.09.2017 | EDITORIAL

Find and Plug the Leak: Improving Adherence to Anti-Hypertensive Medicines

Editorial to: “Assessing Adherence to Antihypertensive Therapy in Primary Health Care in Namibia: Findings and Implications” by M.M. Nashilongo et al.

verfasst von: Benson Njuguna, Rajesh Vedanthan

Erschienen in: Cardiovascular Drugs and Therapy | Ausgabe 5-6/2017

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Excerpt

Elevated blood pressure is the leading preventable cause of cardiovascular disease (CVD) death and disability globally [1, 2]. Adherence to anti-hypertensive medicines is the cornerstone to blood pressure control and subsequent reductions in CVD related death and disability [3]. However, adherence to anti-hypertensive medicines remains suboptimal globally and in sub-Saharan Africa (SSA). A recent systematic review estimated rates of non-adherence to be 45% globally, rising to 63% among African and Asian populations [4]. Furthermore, non-adherence was noted in 84% of patients with uncontrolled hypertension. Hypertension prevalence is highest in Africa (46%) compared to other regions and is expected to increase by more than 65% by 2025 [5, 6]. Consequently, there is an urgent need to implement strategies to monitor and improve adherence to anti-hypertensive medicines in SSA. …
Literatur
1.
Zurück zum Zitat GBD 2015 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet (Lond Engl). 2016;388:1659–724. GBD 2015 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet (Lond Engl). 2016;388:1659–724.
2.
Zurück zum Zitat Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the global burden of disease study 2010. Lancet. 2012;380:2224–60. Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the global burden of disease study 2010. Lancet. 2012;380:2224–60.
3.
Zurück zum Zitat Bundy JD, Li C, Stuchlik P, et al. Systolic blood pressure reduction and risk of cardiovascular disease and mortality: a systematic review and network meta-analysis. JAMA Cardiol. 2017;2(7):775–81.CrossRefPubMed Bundy JD, Li C, Stuchlik P, et al. Systolic blood pressure reduction and risk of cardiovascular disease and mortality: a systematic review and network meta-analysis. JAMA Cardiol. 2017;2(7):775–81.CrossRefPubMed
4.
Zurück zum Zitat Abegaz TM, Shehab A, Gebreyohannes EA, Bhagavathula AS, Elnour AA. Nonadherence to antihypertensive drugs: a systematic review and meta-analysis. Medicine. 2017;96(4):e5641.CrossRefPubMedPubMedCentral Abegaz TM, Shehab A, Gebreyohannes EA, Bhagavathula AS, Elnour AA. Nonadherence to antihypertensive drugs: a systematic review and meta-analysis. Medicine. 2017;96(4):e5641.CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Cappuccio FP, Miller MA. Cardiovascular disease and hypertension in sub-Saharan Africa: burden, risk and interventions. Intern Emerg Med. 2016;11:299–305.CrossRefPubMedPubMedCentral Cappuccio FP, Miller MA. Cardiovascular disease and hypertension in sub-Saharan Africa: burden, risk and interventions. Intern Emerg Med. 2016;11:299–305.CrossRefPubMedPubMedCentral
6.
Zurück zum Zitat Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet. 2005;365:217–23. Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet. 2005;365:217–23.
7.
Zurück zum Zitat Stuckler D, Basu S, McKee M. Drivers of inequality in millennium development goal progress: a statistical analysis. PLoS Med. 2010;7(3):e1000241.CrossRefPubMedPubMedCentral Stuckler D, Basu S, McKee M. Drivers of inequality in millennium development goal progress: a statistical analysis. PLoS Med. 2010;7(3):e1000241.CrossRefPubMedPubMedCentral
8.
Zurück zum Zitat Khatib R, Schwalm J-D, Yusuf S, Haynes RB, McKee M, Khan M, et al. Patient and healthcare provider barriers to hypertension awareness, treatment and follow up: a systematic review and meta-analysis of qualitative and quantitative studies. PLoS One. 2014;9(1):e84238.CrossRefPubMedPubMedCentral Khatib R, Schwalm J-D, Yusuf S, Haynes RB, McKee M, Khan M, et al. Patient and healthcare provider barriers to hypertension awareness, treatment and follow up: a systematic review and meta-analysis of qualitative and quantitative studies. PLoS One. 2014;9(1):e84238.CrossRefPubMedPubMedCentral
9.
Zurück zum Zitat Nashilongo MM, Singu B, Kalemeera F, et al. Assessing adherence to antihypertensive therapy in primary health care in Namibia: findings and implications. Cardiovasc Drugs Ther 2017;31: this issue. Nashilongo MM, Singu B, Kalemeera F, et al. Assessing adherence to antihypertensive therapy in primary health care in Namibia: findings and implications. Cardiovasc Drugs Ther 2017;31: this issue.
10.
Zurück zum Zitat Lulebo AM, Mutombo PB, Mapatano MA, Mafuta EM, Kayembe PK, Ntumba LT, et al. Predictors of non-adherence to antihypertensive medication in Kinshasa, Democratic Republic of Congo: a cross-sectional study. BMC Res Notes. 2015;8:526.CrossRefPubMedPubMedCentral Lulebo AM, Mutombo PB, Mapatano MA, Mafuta EM, Kayembe PK, Ntumba LT, et al. Predictors of non-adherence to antihypertensive medication in Kinshasa, Democratic Republic of Congo: a cross-sectional study. BMC Res Notes. 2015;8:526.CrossRefPubMedPubMedCentral
11.
Zurück zum Zitat Ambaw AD, Alemie GA, WY SM, Mengesha ZB. Adherence to antihypertensive treatment and associated factors among patients on follow up at University of Gondar Hospital, Northwest Ethiopia. BMC Public Health. 2012;12:282.CrossRefPubMedPubMedCentral Ambaw AD, Alemie GA, WY SM, Mengesha ZB. Adherence to antihypertensive treatment and associated factors among patients on follow up at University of Gondar Hospital, Northwest Ethiopia. BMC Public Health. 2012;12:282.CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Ghembaza MA, Senoussaoui Y, Tani MK, Meguenni K. Impact of patient knowledge of hypertension complications on adherence to antihypertensive therapy. Curr Hypertens Rev. 2014;10(1):41–8.CrossRefPubMed Ghembaza MA, Senoussaoui Y, Tani MK, Meguenni K. Impact of patient knowledge of hypertension complications on adherence to antihypertensive therapy. Curr Hypertens Rev. 2014;10(1):41–8.CrossRefPubMed
13.
Zurück zum Zitat Mugomeri E, Ramathebane MV, Maja L, Chatanga P, Moletsane L. Knowledge of disease condition and medications among hypertension patients in Lesotho. J Am Soc Hypertens. 2016;10(1):41–6.CrossRefPubMed Mugomeri E, Ramathebane MV, Maja L, Chatanga P, Moletsane L. Knowledge of disease condition and medications among hypertension patients in Lesotho. J Am Soc Hypertens. 2016;10(1):41–6.CrossRefPubMed
14.
Zurück zum Zitat Goverwa TP, Masuka N, Tshimanga M, Gombe NT, Takundwa L, Bangure D, et al. Uncontrolled hypertension among hypertensive patients on treatment in Lupane District, Zimbabwe, 2012. BMC Res Notes. 2014;7:703.CrossRefPubMedPubMedCentral Goverwa TP, Masuka N, Tshimanga M, Gombe NT, Takundwa L, Bangure D, et al. Uncontrolled hypertension among hypertensive patients on treatment in Lupane District, Zimbabwe, 2012. BMC Res Notes. 2014;7:703.CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Gold DT, McClung B. Approaches to patient education: emphasizing the long-term value of compliance and persistence. Am J Med. 2006;119(4):S32–S7.CrossRefPubMed Gold DT, McClung B. Approaches to patient education: emphasizing the long-term value of compliance and persistence. Am J Med. 2006;119(4):S32–S7.CrossRefPubMed
16.
Zurück zum Zitat Adeyemo A, Tayo BO, Luke A, Ogedegbe O, Durazo-Arvizu R, Cooper RS. The Nigerian anti-hypertensive adherence trial (NA-HAT): a community-based randomized trial. J Hypertens. 2013;31(1):201–7.CrossRefPubMedPubMedCentral Adeyemo A, Tayo BO, Luke A, Ogedegbe O, Durazo-Arvizu R, Cooper RS. The Nigerian anti-hypertensive adherence trial (NA-HAT): a community-based randomized trial. J Hypertens. 2013;31(1):201–7.CrossRefPubMedPubMedCentral
17.
Zurück zum Zitat World Health Organization. Equitable access to essential medicines: a framework for collective action. WHO policy perspectives on medicines no. 8. Geneva: WHO; 2004. World Health Organization. Equitable access to essential medicines: a framework for collective action. WHO policy perspectives on medicines no. 8. Geneva: WHO; 2004.
18.
Zurück zum Zitat Maginga J, Guerrero M, Koh E, Hansen CH, Shedafa R, Kalokola F, et al. Hypertension control and its correlates among adults attending a hypertension clinic in Tanzania. J Clin Hypertens (Greenwich). 2016;18(3):207–16.CrossRef Maginga J, Guerrero M, Koh E, Hansen CH, Shedafa R, Kalokola F, et al. Hypertension control and its correlates among adults attending a hypertension clinic in Tanzania. J Clin Hypertens (Greenwich). 2016;18(3):207–16.CrossRef
19.
Zurück zum Zitat Mugwano I, Kaddumukasa M, Mugenyi L, Kayima J, Ddumba E, Sajatovic M, et al. Poor drug adherence and lack of awareness of hypertension among hypertensive stroke patients in Kampala, Uganda: a cross sectional study. BMC Res Notes. 2016;9:3.CrossRefPubMedPubMedCentral Mugwano I, Kaddumukasa M, Mugenyi L, Kayima J, Ddumba E, Sajatovic M, et al. Poor drug adherence and lack of awareness of hypertension among hypertensive stroke patients in Kampala, Uganda: a cross sectional study. BMC Res Notes. 2016;9:3.CrossRefPubMedPubMedCentral
20.
Zurück zum Zitat Pastakia SD, Manyara SM, Vedanthan R, Kamano JH, Menya D, Andama B, et al. Impact of bridging income generation with group integrated care (BIGPIC) on hypertension and diabetes in rural western Kenya. J Gen Intern Med. 2017;32(5):540–8.CrossRefPubMed Pastakia SD, Manyara SM, Vedanthan R, Kamano JH, Menya D, Andama B, et al. Impact of bridging income generation with group integrated care (BIGPIC) on hypertension and diabetes in rural western Kenya. J Gen Intern Med. 2017;32(5):540–8.CrossRefPubMed
21.
Zurück zum Zitat Vedanthan R, Kamano JH, Lee H, Andama B, Bloomfield GS, DeLong AK, et al. Bridging income generation with group integrated care for cardiovascular risk reduction: rationale and design of the BIGPIC study. Am Heart J. 2017;188:175–85.CrossRefPubMed Vedanthan R, Kamano JH, Lee H, Andama B, Bloomfield GS, DeLong AK, et al. Bridging income generation with group integrated care for cardiovascular risk reduction: rationale and design of the BIGPIC study. Am Heart J. 2017;188:175–85.CrossRefPubMed
22.
Zurück zum Zitat Vedanthan R, Kamano JH, Bloomfield GS, Manji I, Pastakia S, Kimaiyo SN. Engaging the entire care Cascade in western Kenya: a model to achieve the cardiovascular disease secondary prevention roadmap goals. Glob Heart. 2015;10(4):313–7.CrossRefPubMedPubMedCentral Vedanthan R, Kamano JH, Bloomfield GS, Manji I, Pastakia S, Kimaiyo SN. Engaging the entire care Cascade in western Kenya: a model to achieve the cardiovascular disease secondary prevention roadmap goals. Glob Heart. 2015;10(4):313–7.CrossRefPubMedPubMedCentral
23.
Zurück zum Zitat Khabala KB, Edwards JK, Baruani B, Sirengo M, Musembi P, Kosgei RJ, et al. Medication adherence clubs: a potential solution to managing large numbers of stable patients with multiple chronic diseases in informal settlements. Tropical Med Int Health. 2015;20(10):1265–70.CrossRef Khabala KB, Edwards JK, Baruani B, Sirengo M, Musembi P, Kosgei RJ, et al. Medication adherence clubs: a potential solution to managing large numbers of stable patients with multiple chronic diseases in informal settlements. Tropical Med Int Health. 2015;20(10):1265–70.CrossRef
24.
Zurück zum Zitat Ford N, Nachega JB, Engel ME, Mills EJ. Directly observed antiretroviral therapy: a systematic review and meta-analysis of randomised clinical trials. Lancet. 2009;374:2064–71. Ford N, Nachega JB, Engel ME, Mills EJ. Directly observed antiretroviral therapy: a systematic review and meta-analysis of randomised clinical trials. Lancet. 2009;374:2064–71.
25.
Zurück zum Zitat Tran DN, Njuguna B, Mercer T, Manji I, Fischer L, Lieberman M, et al. Ensuring patient-centered access to cardiovascular disease medicines in low-income and middle-income countries through health-system strengthening. Cardiol Clin. 2017;35(1):125–34.CrossRefPubMed Tran DN, Njuguna B, Mercer T, Manji I, Fischer L, Lieberman M, et al. Ensuring patient-centered access to cardiovascular disease medicines in low-income and middle-income countries through health-system strengthening. Cardiol Clin. 2017;35(1):125–34.CrossRefPubMed
Metadaten
Titel
Find and Plug the Leak: Improving Adherence to Anti-Hypertensive Medicines
Editorial to: “Assessing Adherence to Antihypertensive Therapy in Primary Health Care in Namibia: Findings and Implications” by M.M. Nashilongo et al.
verfasst von
Benson Njuguna
Rajesh Vedanthan
Publikationsdatum
30.09.2017
Verlag
Springer US
Erschienen in
Cardiovascular Drugs and Therapy / Ausgabe 5-6/2017
Print ISSN: 0920-3206
Elektronische ISSN: 1573-7241
DOI
https://doi.org/10.1007/s10557-017-6753-y

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