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Current Allergy and Asthma Reports
Erschienen in: Current Allergy and Asthma Reports 2/2013

01.04.2013 | RHINITIS (JN BARANIUK AND JJ OPPENHEIMER, SECTION EDITORS)

Fungal Disease of the Nose and Sinuses: An Updated Overview

verfasst von: Christopher Chang, M. Eric Gershwin, George R. Thompson III

Erschienen in: Current Allergy and Asthma Reports | Ausgabe 2/2013

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Abstract

Fungal diseases of the nose and sinuses encompasses a diverse spectrum of disease. Clinical manifestations are largely dependent upon the immune status of the host, as, given the ubiquitous nature of these organisms, exposure is unavoidable. Asymptomatic colonization of the nasal passages by fungi warrants no treatment and is common, while allergic fungal rhinosinusitis is challenging and often requires a combined approach of surgical intervention, immunotherapy, and corticosteroid administration. A diagnosis requires a combination of IgE immune reactivity, eosinophilic infiltration, and fungi recovery. Similarly, invasive disease may present only after several months of slowly progressive disease, or in rapid and fulminant fashion in the appropriate host. A differentiation of these overlapping syndromes and the pathophysiologic processes at play, and recommended treatment algorithms, are the focus of this review.
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Metadaten
Titel
Fungal Disease of the Nose and Sinuses: An Updated Overview
verfasst von
Christopher Chang
M. Eric Gershwin
George R. Thompson III
Publikationsdatum
01.04.2013
Verlag
Current Science Inc.
Erschienen in
Current Allergy and Asthma Reports / Ausgabe 2/2013
Print ISSN: 1529-7322
Elektronische ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-012-0320-1

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