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Cancer and Metastasis Reviews

Erschienen in:

01.03.2011

Future perspectives on neuroendocrine tumors

verfasst von: Daniel Castellano, Ramón Salazar, Eric Raymond

Erschienen in: Cancer and Metastasis Reviews | Sonderheft 1/2011

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Abstract

In the last 30 years the incidence and prevalence of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) has increased substantially. This could be partly due to improvements in diagnostic imaging, which lead to the incidental diagnosis of asymptomatic cases. However, despite these improvements, patients typically experience long delays before they are diagnosed. In this review, we discuss both the limitations and advances in our understanding of the pathogenesis, molecular and cellular biology, diagnosis, classification, staging, and treatment of GEP-NETs in order to identify which factors could be contributing to the delay in diagnosis and timely treatment of these patients. Within this context, the results from the most relevant clinical trials the available targeted therapies for the treatment of GEP-NETs, such as the “RAD001 in Advanced Neuroendocrine Tumors,” will be discussed.

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Titel: Future perspectives on neuroendocrine tumors
verfasst von: Daniel Castellano
Ramón Salazar
Eric Raymond
Publikationsdatum: 01.03.2011
Verlag: Springer US
Erschienen in: Cancer and Metastasis Reviews / Ausgabe Sonderheft 1/2011
Print ISSN: 0167-7659
Elektronische ISSN: 1573-7233
DOI: https://doi.org/10.1007/s10555-011-9294-z

Springer Medizin

Future perspectives on neuroendocrine tumors

Abstract

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