Interventions should be more aggressive towards modifiable risk factors (unhealthy diets—excessive salt consumption, a diet high in saturated fat and trans fats, low intake of fruits and vegetables; physical inactivity; consumption of tobacco and alcohol; and being overweight or obese) in PLHIV globally [
7]. In LICs, especially those in Africa and Asia with the highest burden of HIV infection and the poorest indicators for HIV programs, the HIV care cascade (early HIV diagnosis, early HAART initiation and linkage to care, high level of linkage to care, and adherence to HAART) should continue to be improved, building on the encouraging achievements of past two decades [
8]. Furthermore, there should be a more effective integration of services for HIV and non-communicable diseases including hypertension, diabetes, and dyslipidemia. Interventions for primordial cardiovascular prevention should be central in healthcare provision for PLHIV in these resource-limited settings, as there are more likely to be cost-effective. It is also crucial to ensure that all PLHIV have adequate access to screening and management of cardiovascular risk factors such as hypertension, considering the low level of awareness, treatment, and control of these conditions in the general population [
9]. In the context of limited specialized healthcare personnel, task shifting represents a viable solution.