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01.07.2013 | Brief Report

High prevalence of torque teno sus virus in China and genetic diversity of the 5’ non-coding region

verfasst von: Shao-Lun Zhai, Jin-Xue Long, Wen-Kang Wei, Qin-Ling Chen, Man-Lin Luo, Dian-Hong Lv, Da-Cheng Wu, Fei Gao, Shi-Shan Yuan, Guang-Zhi Tong, Zu-Zhang Wei

Erschienen in: Archives of Virology | Ausgabe 7/2013

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Abstract

Members of the family Anelloviridae are emerging circular DNA viruses infecting many species of vertebrates including pigs. To date, members of two distinct genera, Iotatorquevirus, including torque teno sus virus 1a and torque teno sus virus 1b (TTSuV1a and TTSuV1b), and Kappatorquevirus, including torque teno sus virus k2a and torque teno sus virus k2b (TTSuVk2a and TTSuVk2b), have been identified in domestic pigs and wild boars. The goal of this study was to evaluate the prevalence and genetic diversity of these viruses based on 5’ non-coding genes in Chinese swine herds experiencing clinical symptoms. One hundred eighty-five clinical samples from 11 different regions, collected during 2008-2009, were analyzed using a PCR method, and the results revealed a high TTSuV-positive rate of 78.9 % (146/185) in pigs. Moreover, we detected co-infection with multiple TTSuV strains in the same pig. Nucleotide sequencing results revealed greater genetic diversity within the genus Kappatorquevirus than within the genus Iotatorquevirus. In addition, TTSuVk2b, a novel virus discovered in New Zealand in 2012, was also identified in this study. In summary, the present work helps us obtain more knowledge about the epidemiology and genetic diversity of TTSuVs.

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Titel: High prevalence of torque teno sus virus in China and genetic diversity of the 5’ non-coding region
verfasst von: Shao-Lun Zhai
Jin-Xue Long
Wen-Kang Wei
Qin-Ling Chen
Man-Lin Luo
Dian-Hong Lv
Da-Cheng Wu
Fei Gao
Shi-Shan Yuan
Guang-Zhi Tong
Zu-Zhang Wei
Publikationsdatum: 01.07.2013
Verlag: Springer Vienna
Erschienen in: Archives of Virology / Ausgabe 7/2013
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-013-1644-4

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