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Erschienen in: Lung 5/2019

16.08.2019 | COUGH

Impact of Cough and Unmet Needs in Chronic Cough: A Survey of Patients in Korea

verfasst von: Sung-Yoon Kang, Ha-Kyeong Won, Sang Min Lee, Jae-Woo Kwon, Min-Hye Kim, Eun-Jung Jo, Seung-Eun Lee, Sae-Hoon Kim, Yoon-Seok Chang, Sang Pyo Lee, Byung-Jae Lee, Sang-Heon Cho, Surinder S. Birring, Woo-Jung Song

Erschienen in: Lung | Ausgabe 5/2019

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Abstract

Purpose

Chronic cough is a common problem in various populations. The present study assessed the impact of cough and unmet needs in Korean patients with chronic cough.

Methods

This cross-sectional multi-center study enrolled adult patients newly referred to clinic for assessment of chronic cough. A second group of patients with unexplained chronic cough following detailed assessment were recruited for comparison. Patients completed self-reported questionnaires, including cough characteristics, impact of cough on daily life, and unmet needs.

Results

A total of 447 subjects were recruited from six referral clinics, including 408 with chronic cough and 39 with unexplained chronic cough. Almost all patients reported that cough impacted their daily lives. Psychosocial impacts were more evident in unexplained cough patients compared to newly referred patients. Approximately 75% of newly referred patients had previously sought medical care for cough on multiple occasions, but the effectiveness of treatment was limited (70.3%) or absent (17.3%). The most frequent unmet need was the ineffectiveness of treatment (49.3%), followed by unclear diagnosis (30.1%). The majority of participants ( > 80%) expressed the need for further information on accessing cough specialists and disease management. The main problem faced by unexplained cough patients was poor cough control despite treatment (64%).

Conclusions

Chronic cough has a substantial impact on daily life and is worst in those whose cough remains unexplained following assessment. Ineffectiveness of treatment and unclear diagnosis were major unmet needs. Medical information about chronic cough was also lacking. Improvements in the management of chronic cough patients in Korea are necessary.
Literatur
1.
Zurück zum Zitat Song WJ, Chang YS, Faruqi S, Kim JY, Kang MG, Kim S et al (2015) The global epidemiology of chronic cough in adults: a systematic review and meta-analysis. Eur Respir J 45:1479–1481CrossRef Song WJ, Chang YS, Faruqi S, Kim JY, Kang MG, Kim S et al (2015) The global epidemiology of chronic cough in adults: a systematic review and meta-analysis. Eur Respir J 45:1479–1481CrossRef
2.
Zurück zum Zitat Morice AH, Millqvist E, Belvisi MG, Bieksiene K, Birring SS, Chung KF et al (2014) Expert opinion on the cough hypersensitivity syndrome in respiratory medicine. Eur Respir J 44:1132–1148CrossRef Morice AH, Millqvist E, Belvisi MG, Bieksiene K, Birring SS, Chung KF et al (2014) Expert opinion on the cough hypersensitivity syndrome in respiratory medicine. Eur Respir J 44:1132–1148CrossRef
3.
Zurück zum Zitat Morice AH, Fontana GA, Sovijarvi AR, Pistolesi M, Chung KF, Widdicombe J et al (2004) The diagnosis and management of chronic cough. Eur Respir J 24:481–492CrossRef Morice AH, Fontana GA, Sovijarvi AR, Pistolesi M, Chung KF, Widdicombe J et al (2004) The diagnosis and management of chronic cough. Eur Respir J 24:481–492CrossRef
4.
Zurück zum Zitat Irwin RS, Baumann MH, Bolser DC, Boulet LP, Braman SS, Brightling CE et al (2006) Diagnosis and management of cough executive summary: accp evidence-based clinical practice guidelines. Chest 129:1S–23SCrossRef Irwin RS, Baumann MH, Bolser DC, Boulet LP, Braman SS, Brightling CE et al (2006) Diagnosis and management of cough executive summary: accp evidence-based clinical practice guidelines. Chest 129:1S–23SCrossRef
5.
Zurück zum Zitat Mcgarvey L (2013) The difficult-to-treat, therapy-resistant cough: why are current cough treatments not working and what can we do? Pulm Pharmacol Ther 26:528–531CrossRef Mcgarvey L (2013) The difficult-to-treat, therapy-resistant cough: why are current cough treatments not working and what can we do? Pulm Pharmacol Ther 26:528–531CrossRef
6.
Zurück zum Zitat Birring SS, Prudon B, Carr AJ, Singh SJ, Morgan MD, Pavord ID (2003) Development of a symptom specific health status measure for patients with chronic cough: Leicester Cough Questionnaire (LCQ). Thorax 58:339–343CrossRef Birring SS, Prudon B, Carr AJ, Singh SJ, Morgan MD, Pavord ID (2003) Development of a symptom specific health status measure for patients with chronic cough: Leicester Cough Questionnaire (LCQ). Thorax 58:339–343CrossRef
7.
Zurück zum Zitat French CL, Irwin RS, Curley FJ, Krikorian CJ (1998) Impact of chronic cough on quality of life. Arch Intern Med 158:1657–1661CrossRef French CL, Irwin RS, Curley FJ, Krikorian CJ (1998) Impact of chronic cough on quality of life. Arch Intern Med 158:1657–1661CrossRef
8.
Zurück zum Zitat Song WJ, Morice AH, Kim MH, Lee SE, Jo EJ, Lee SM et al (2013) Cough in the elderly population: relationships with multiple comorbidity. PLoS ONE 8:E78081CrossRef Song WJ, Morice AH, Kim MH, Lee SE, Jo EJ, Lee SM et al (2013) Cough in the elderly population: relationships with multiple comorbidity. PLoS ONE 8:E78081CrossRef
9.
Zurück zum Zitat Chamberlain SA, Garrod R, Douiri A, Masefield S, Powell P, Bucher C et al (2015) The impact of chronic cough: a cross-sectional European Survey. Lung 193:401–408CrossRef Chamberlain SA, Garrod R, Douiri A, Masefield S, Powell P, Bucher C et al (2015) The impact of chronic cough: a cross-sectional European Survey. Lung 193:401–408CrossRef
10.
Zurück zum Zitat Song DJ, Song WJ, Kwon JW, Kim GW, Kim MA, Kim MY et al (2018) KAAACI evidence-based clinical practice guidelines for chronic cough in adults and children in Korea. Allergy Asthma Immunol Res 10:591–613CrossRef Song DJ, Song WJ, Kwon JW, Kim GW, Kim MA, Kim MY et al (2018) KAAACI evidence-based clinical practice guidelines for chronic cough in adults and children in Korea. Allergy Asthma Immunol Res 10:591–613CrossRef
11.
Zurück zum Zitat Song W-J, Lee S-H, Kang M-G, Kim J-Y, Kim M-Y, Jo E-J et al (2015) Validation of the korean version of the European Community Respiratory Health Survey Screening Questionnaire for use in epidemiologic studies for adult asthma. Asia Pac Allergy 5:25–31CrossRef Song W-J, Lee S-H, Kang M-G, Kim J-Y, Kim M-Y, Jo E-J et al (2015) Validation of the korean version of the European Community Respiratory Health Survey Screening Questionnaire for use in epidemiologic studies for adult asthma. Asia Pac Allergy 5:25–31CrossRef
12.
Zurück zum Zitat Morice AH (2015) Over-the-counter cough medicines: new approaches. Pulm Pharmacol Ther 35:149–151CrossRef Morice AH (2015) Over-the-counter cough medicines: new approaches. Pulm Pharmacol Ther 35:149–151CrossRef
13.
Zurück zum Zitat Morice AH, Menon MS, Mulrennan SA, Everett CF, Wright C, Jackson J et al (2007) Opiate therapy in chronic cough. Am J Respir Crit Care Med 175:312–315CrossRef Morice AH, Menon MS, Mulrennan SA, Everett CF, Wright C, Jackson J et al (2007) Opiate therapy in chronic cough. Am J Respir Crit Care Med 175:312–315CrossRef
14.
Zurück zum Zitat Ryan NM, Birring SS, Gibson PG (2012) Gabapentin for refractory chronic cough: a randomised, double-blind, placebo-controlled trial. Lancet 380:1583–1589CrossRef Ryan NM, Birring SS, Gibson PG (2012) Gabapentin for refractory chronic cough: a randomised, double-blind, placebo-controlled trial. Lancet 380:1583–1589CrossRef
15.
Zurück zum Zitat Faruqi S, Murdoch RD, Allum F, Morice AH (2014) On the definition of chronic cough and current treatment pathways: an International Qualitative Study. Cough 10:5CrossRef Faruqi S, Murdoch RD, Allum F, Morice AH (2014) On the definition of chronic cough and current treatment pathways: an International Qualitative Study. Cough 10:5CrossRef
16.
Zurück zum Zitat Chung KF, Mcgarvey L, Mazzone SB (2013) Chronic cough as a neuropathic disorder. Lancet Respir Med 1:414–422CrossRef Chung KF, Mcgarvey L, Mazzone SB (2013) Chronic cough as a neuropathic disorder. Lancet Respir Med 1:414–422CrossRef
17.
Zurück zum Zitat Song WJ, Morice AH (2017) Cough hypersensitivity syndrome: a few more steps forward. Allergy Asthma Immunol Res 9:394–402CrossRef Song WJ, Morice AH (2017) Cough hypersensitivity syndrome: a few more steps forward. Allergy Asthma Immunol Res 9:394–402CrossRef
18.
Zurück zum Zitat Polley L, Yaman N, Heaney L, Cardwell C, Murtagh E, Ramsey J et al (2008) Impact of cough across different chronic respiratory diseases: comparison of two cough-specific health-related quality of life questionnaires. Chest 134:295–302CrossRef Polley L, Yaman N, Heaney L, Cardwell C, Murtagh E, Ramsey J et al (2008) Impact of cough across different chronic respiratory diseases: comparison of two cough-specific health-related quality of life questionnaires. Chest 134:295–302CrossRef
Metadaten
Titel
Impact of Cough and Unmet Needs in Chronic Cough: A Survey of Patients in Korea
verfasst von
Sung-Yoon Kang
Ha-Kyeong Won
Sang Min Lee
Jae-Woo Kwon
Min-Hye Kim
Eun-Jung Jo
Seung-Eun Lee
Sae-Hoon Kim
Yoon-Seok Chang
Sang Pyo Lee
Byung-Jae Lee
Sang-Heon Cho
Surinder S. Birring
Woo-Jung Song
Publikationsdatum
16.08.2019
Verlag
Springer US
Erschienen in
Lung / Ausgabe 5/2019
Print ISSN: 0341-2040
Elektronische ISSN: 1432-1750
DOI
https://doi.org/10.1007/s00408-019-00258-9

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