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24.07.2020 | BRONCHOSCOPIC LUNG VOLUME REDUCTION Open Access

Change in Dynamic Hyperinflation After Bronchoscopic Lung Volume Reduction in Patients with Emphysema

In patients with severe emphysema chronic inflammation results in airway and lung parenchyma damage which is associated with reduced lung elastic recoil and increased airway resistance [ 1 ]. The combination of reduced elastic recoil and increased …

23.07.2020 | EXTRACORPOREAL MEMBRANE OXYGENATION

Don’t Drive Blind: Driving Pressure to Optimize Ventilator Management in ECMO

The past decade has seen an increased utilization of extracorporeal membrane oxygenation (ECMO) as a life sustaining strategy for respiratory and/or cardiac failure [ 1 ]. Veno-venous (VV)-ECMO is used to provide temporary gas exchange support in …

22.07.2020 | LUNG TRANSPLANTATION

Risk Factors for Cytomegalovirus Reactivation in Lung Transplant Recipients

Cytomegalovirus (CMV) is a beta-herpesvirus which causes opportunistic infections in immunocompromised patients [ 1 ], especially transplant recipients. The effects of CMV infection on the transplanted lung are significant [ 2 ]. The incidence of …

20.07.2020 | ASTHMA

Mepolizumab and Benralizumab in Severe Eosinophilic Asthma: Preliminary Results of a Proteomic Study

Benralizumab and mepolizumab are new therapies for severe eosinophilic asthma. They are both humanized IgG antibodies, targeting the IL‐5 receptor and IL‐5, respectively, suppressing the corresponding pathways. No specific biomarkers have been …

18.07.2020 | LUNG CANCER

Negative Lymph Node Count Predicts Survival of Resected Non-small Cell Lung Cancer

Lung cancer is the number one leading cause of cancer mortality in the USA [ 1 ]. Although patients with early-stage non-small cell lung cancer (NSCLC) have the possibility to be treated by surgery, the postresection five-year survival rate is …

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