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01.11.2012 | Brief Communication

Impact of depression on quality of life in people living with human T cell lymphotropic virus type 1 (HTLV-1) in Salvador, Brazil

verfasst von: Ana Verena Galvão-Castro, Ney Boa-Sorte, Ramon Almeida Kruschewsky, Maria Fernanda Rios Grassi, Bernardo Galvão-Castro

Erschienen in: Quality of Life Research | Ausgabe 9/2012

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Abstract

Purpose

A previous study found the prevalence of depression in HTLV-1-infected patients to be approximately 30%, but few studies have attempted to correlate depression with quality of life (QOL) in these patients. The present study investigates the association between depression and QOL in people living with HTLV-1.

Methods

A clinical-epidemiological questionnaire, the Mini International Neuropsychiatric Interview and the WHOQOL-Bref were applied to 88 HTLV-1-infected patients (32 with TSP/HAM) at the HTLV Center of the Bahiana School of Medicine and Public Health, Salvador, Brazil.

Results

The prevalence of depression among people living with HTLV-1 was 34.1%. Depression was significantly associated with a poor QOL in the physical, psychological, social relationship and environment domains, when controlling for other variables, such as gender, age, time of knowledge of serological diagnosis and presence of tropical spastic paraparesis/HTLV-1associated myelopathy (TSP/HAM). Moreover, patients with TSP/HAM experienced a reduction in their QOL in the physical, psychological and environment domains.

Conclusion

Our results showed that depression negatively affects the quality of life of people living with HTLV-1, regardless of the presence of TSP/HAM. Since it is possible to improve a patient’s QOL by treating depression, psychological evaluations are strongly recommended as a measure to integrate the treatment protocols of HTLV-1 intervention programs.

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Titel: Impact of depression on quality of life in people living with human T cell lymphotropic virus type 1 (HTLV-1) in Salvador, Brazil
verfasst von: Ana Verena Galvão-Castro
Ney Boa-Sorte
Ramon Almeida Kruschewsky
Maria Fernanda Rios Grassi
Bernardo Galvão-Castro
Publikationsdatum: 01.11.2012
Verlag: Springer Netherlands
Erschienen in: Quality of Life Research / Ausgabe 9/2012
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-011-0066-6

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusion

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