Erschienen in:
07.01.2021 | Brief Report
Impact of surgical timing on survival in patients with infective endocarditis: a time-dependent analysis
verfasst von:
Marco Ripa, Stefania Chiappetta, Barbara Castiglioni, Eustachio Agricola, Elena Busnardo, Silvia Carletti, Alessandro Castiglioni, Michele De Bonis, Giovanni La Canna, Chiara Oltolini, Ursola Pajoro, Renée Pasciuta, Chiara Tassan Din, Paolo Scarpellini, on behalf of Ospedale San Raffaele Endocarditis Team
Erschienen in:
European Journal of Clinical Microbiology & Infectious Diseases
|
Ausgabe 6/2021
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Abstract
The purpose of this study was to evaluate the impact of surgical timing on survival in patients with left-sided infective endocarditis (IE). This was a retrospective study including 313 patients with left-sided IE between 2009 and 2017. Surgery was defined as urgent (US) or early (ES) if performed within 7 or 28 days, respectively. A multivariable Cox regression analysis including US and ES as time-dependent variables was performed to assess the impact on 1-year mortality. ES was associated with a better survival (aHR 0.349, 95% CI 0.135–0.902), as US (aHR 0.262, 95% CI 0.075–0.915). ES and US were associated with a better prognosis in patients with left-sided IE.