Erschienen in:
01.10.2015 | Letter to the Editor
Improvement of Kidney Function Following Bariatric Surgery: Hope or Illusion?
verfasst von:
G. Favre, A. S. Schneck, R. Anty, V. L. M. Esnault, A. Iannelli
Erschienen in:
Obesity Surgery
|
Ausgabe 10/2015
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Excerpt
Many studies have established obesity as an independent risk factor for kidney diseases. The question whether bariatric surgery could slow the progression of chronic kidney disease (CKD) is of paramount importance given the parallel increase in the prevalence of obesity and CKD. The latter is characterized by a glomerular filtration rate (GFR) <60 ml/min/1.73 m2 and by a low reserve in filtration capacity. Obesity is a reversible cause of stimulation of the reserve of filtration capacity called glomerular hyperfiltration, which is harmful to kidney function in the long term. Furthermore, obesity is associated with the reversible production of adipocytokines, which may directly damage the kidneys. Therefore, a beneficial effect of bariatric surgery on kidney function can be anticipated. However, the appreciation of GFR in extreme obese patients is difficult and available studies on this topic should be cautiously interpreted. In the present letter, we would like to briefly review the evidence for the hope and doubts regarding the benefit of bariatric surgery in CKD patients. …
