Background
Methods
Eligibility
Ethics and consent
Staging
Surgery
Follow-up
Data analysis
Results
General characteristics
All patients | Without lymph node involvement | With lymph node involvement | p-value | ||||
---|---|---|---|---|---|---|---|
Characteristic | No. | % | No. | % | No. | % | |
Mean age (years) | 60.6 | 60.25 | 62.28 | ||||
SD | 12.45 | 12.45 | 12.39 | ||||
Range | 30-91 | 30-91 | 30-91 | ||||
Sex | |||||||
Woman | 105 | 32.1 | 82 | 78.1 | 23 | 21.9 | 0.215 |
Men | 222 | 67.9 | 184 | 82.9 | 38 | 17.1 | |
Performance status | |||||||
Dead | 129 | 39.4 | 98 | 76.0 | 31 | 24.0 | 0.074 |
Alive | 198 | 60.6 | 168 | 84.8 | 30 | 15.2 | |
Tumor stage | |||||||
1 | 193 | 59.0 | 175 | 90.6 | 18 | 9.3 | < 0.001* |
2 | 134 | 41.0 | 91 | 67.9 | 43 | 32.1 | |
N stage | |||||||
0 | 266 | 81.3 | 266 | 100 | |||
1 | 61 | 18.7 | 61 | 100 | |||
Tumor grade | |||||||
1 | 52 | 15.9 | 48 | 92.3 | 4 | 7.7 | |
2 | 236 | 72.2 | 198 | 83.9 | 38 | 16.1 | < 0.001* |
3 | 39 | 11.9 | 20 | 51.3 | 19 | 48.7 | |
Recurrence | |||||||
0 | 257 | 78.6 | 214 | 83.3 | 43 | 16.7 | 0.083 |
1 | 70 | 21.4 | 52 | 74.3 | 18 | 25.7 |
Outcome
Univariate analysis
Variable | Hazard ratio | 95% CI | p |
---|---|---|---|
Age | 1.03 | 1.02 to 1.03 | < 0.0001* |
Tumor stage | 1.252 | 1.16 to 1.35 | = 0.01* |
N stage | 1.60 | 1.44 to 1.77 | = 0.049* |
Tumor grade | 1.46 | 1.21 to 1.76 | = 0.002* |
Sex | 1.02 | 0.83 to 1.25 | 0.365 |
Recurrence | 1.23 | 1.00 to 1.52 | 0.911 |
Multivariate analysis
Variable | Hazard ratio | 95% CI | p |
---|---|---|---|
Age | 1.04 | 1.02 to 1.05 | < 0.0001* |
Sex | 1.11 | 0.73 to 1.71 | = 0.622 |
Tumor stage | 1.48 | 1.09 to 2.0 | = 0.011* |
N stage | 1.68 | 1.04 to 2.74 | = 0.034* |
Recurrence | 1.79 | 1.09 to 2.98 | = 0.022* |
Tumor grade | 1.54 | 1.16 to 2.05 | = 0.003* |