Background
Methods
Ethics statement
Data sources
Patients
Outcomes and comorbidities
Statistical analysis
Results
Patient characteristics
Non-ESRD (n = 5094) | ESRD (n = 3564) | |
---|---|---|
Age | ||
≦39 | 412 (8.1a) | 265 (7.4) |
40–49 | 677 (13.3) | 406 (11.4) |
50–59 | 1137 (22.3) | 772 (21.7) |
60–69 | 1180 (23.2) | 849 (23.8) |
≧70 | 1688 (33.1) | 1272 (35.7) |
Mean ± SD | 61.84 ± 15.00 | 62.76 ± 14.69 |
Gender | ||
Male | 2499 (49.1) | 1762 (49.4) |
Female | 2595 (50.9) | 1802 (50.6) |
Deep vein thrombosis | 26 (0.5) | 200 (5.6) |
Comorbidities | ||
Atrial fibrillation | 24 (0.5) | 64 (1.8) |
Hypertension | 1369 (26.9) | 2024 (56.8) |
Diabetes | 684 (13.4) | 1404 (39.4) |
Hyperlipidemia | 63 (1.2) | 208 (5.8) |
Cerebrovascular accident | 135 (2.7) | 394 (11.1) |
Congestive heart failure | 65 (1.3) | 616 (17.3) |
Lower leg fracture or surgery | 28 (0.5) | 44 (1.2) |
Cancer | 99 (1.9) | 82 (2.3) |
Incidence of DVT
Characteristics | Non-ESRD (n = 5094) | ESRD (n = 3564) | ||||||
---|---|---|---|---|---|---|---|---|
Event | TFP (PY) | IR | Event | TFP (PY) | IR | aHR (95% CI) |
P
| |
DVT | 26 | 18,112.37 | 1.46 | 200 | 9552.35 | 20.94 | 13.92 (9.25–20.95) | < 0.001 |
Age | ||||||||
≦39 | 2 | 1767.13 | 1.13 | 13 | 1004.83 | 12.94 | 10.99 (2.48–48.73) | 0.002 |
40–49 | 1 | 2729.76 | 0.37 | 20 | 1477.39 | 13.54 | 36.76 (4.93–273.0) | < 0.001 |
50–59 | 5 | 4334.96 | 1.15 | 47 | 2348.80 | 20.01 | 15.96 (6.34–40.15) | < 0.001 |
60–69 | 7 | 4303.83 | 1.63 | 58 | 2270.50 | 25.55 | 15.25 (6.95–33.46) | < 0.01 |
≧70 | 11 | 4976.70 | 2.21 | 62 | 2450.81 | 25.30 | 11.06 (5.81–21.06) | < 0.01 |
Gender | ||||||||
Male | 10 | 8833.28 | 1.13 | 91 | 4745.28 | 19.18 | 16.31 (8.49–31.36) | < 0.001 |
Female | 16 | 9279.10 | 1.72 | 109 | 4807.06 | 22.67 | 12.46 (7.37–21.08) | < 0.01 |
Comorbidities | ||||||||
Hypertension | ||||||||
Yes | 8 | 4974.73 | 1.61 | 125 | 5714.18 | 21.88 | 13.21 (6.46–27.02) | < 0.001 |
No | 18 | 13,137.64 | 1.37 | 75 | 3838.16 | 19.54 | 13.61 (8.13–22.79) | < 0.001 |
Diabetes | ||||||||
Yes | 4 | 2515.32 | 1.59 | 89 | 3607.59 | 24.67 | 15.01 (5.50–40.93) | < 0.01 |
No | 22 | 15,597.06 | 1.41 | 111 | 5944.75 | 18.67 | 12.72 (8.05–20.10) | < 0.01 |
Hyperlipidemia | ||||||||
Yes | 0 | 217.13 | 0 | 19 | 525.90 | 36.13 | 34.41 (0.50–2985) | .102 |
No | 26 | 17,895.24 | 1.45 | 181 | 9026.45 | 20.05 | 13.17 (8.73–19.88) | < 0.01 |
Cerebrovascular accident | ||||||||
Yes | 1 | 391.38 | 2.55 | 18 | 901.44 | 19.97 | 7.48 (1.00–56.07) | 0.05 |
No | 25 | 17,720.00 | 1.41 | 182 | 8650.90 | 21.04 | 14.29 (9.40–21.71) | < 0.01 |
Congestive heart failure | ||||||||
Yes | 0 | 184.50 | 0 | 30 | 1304.25 | 23.00 | 24.50 (0.20–3057) | .194 |
No | 26 | 17,927.88 | 1.45 | 170 | 8248.09 | 20.61 | 13.68 (9.05–20.68) | < 0.01 |
Lower leg fracture or surgery | ||||||||
Yes | 0 | 90.47 | 0 | 4 | 87.07 | 45.94 | 68.62 (0.02–241,330) | .310 |
No | 26 | 18,021.90 | 1.44 | 196 | 9465.28 | 20.70 | 13.71 (9.10–20.65) | < 0.01 |
Cancer | ||||||||
Yes | 1 | 281.68 | 3.55 | 3 | 153.36 | 19.56 | 4.40 (0.46–42.45) | .201 |
No | 25 | 17,830.70 | 1.40 | 197 | 9398.99 | 20.96 | 14.30 (9.43–21.69) | < 0.01 |
DVT occurring with other risk factors
Variable | Number (%) | Events | Rate | aHR (95% CI) |
P
|
---|---|---|---|---|---|
Age > =50 years | 2893 (81.20) | 167 | 0.06 | 1.65 (1.13–2.40) | 0.01 |
Hypertension | 2024 (56.80) | 125 | 0.06 | 1.10 (0.83–1.47) | 0.52 |
Diabetes | 1404 (39.39) | 89 | 0.06 | 1.26 (0.95–1.67) | 0.11 |
Hyperlipidemia | 208 (5.84) | 19 | 0.09 | 1.73 (1.08–2.78) | 0.02 |
Cerebrovascular accident | 394 (11.05) | 18 | 0.05 | 0.90 (0.56–1.47) | 0.68 |
Congestive heart failure | 616 (17.28) | 30 | 0.05 | 1.04 (0.70–1.53) | 0.86 |
Atrial fibrillation | 64 (1.80) | 2 | 0.03 | 0.77 (0.19–3.10) | 0.71 |
Lower leg fracture or surgery | 44 (1.23) | 4 | 0.09 | 2.04 (0.76–5.48) | 0.16 |
Cancer | 82 (2.30) | 3 | 0.04 | 0.89 (0.28–2.78) | 0.84 |
≥1 comorbidity | 2547 (71.46) | 151 | 0.06 | 1.14 (0.83–1.58) | 0.43 |
≥2 comorbidities | 1509 (42.34) | 88 | 0.06 | 1.13 (0.86–1.50) | 0.39 |
≥3 comorbidities | 630 (17.68) | 43 | 0.07 | 1.45 (1.03–2.03) | 0.03 |