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Erschienen in: Infection 2/2016

23.02.2016 | Review

Infectious diseases consultations can make the difference: a brief review and a plea for more infectious diseases specialists in Germany

verfasst von: Siegbert Rieg, Marc Fabian Küpper

Erschienen in: Infection | Ausgabe 2/2016

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Abstract

Trained infectious diseases (ID) specialists are an integral part of inpatient and outpatient care in many countries, however, these specialized services are established only in selected tertiary care hospitals in Germany. This review summarises studies that addressed the impact of ID consultation services on patient care and outcome. Extensive data for a clinical benefit is available in the context of Staphylococcus aureus bacteremia (SAB), in which in-hospital or 30-day mortality was significantly reduced by 40–50 % in patients evaluated and treated in cooperation with ID consultants. This effect was associated with improved adherence to quality-of-care standards. Moreover, newer studies show a reduced length of hospital stay due to ID consultations, especially if patients are evaluated early in the course of their hospital stay. Of note, informal consultations do not seem to be equivalent to a formal ID consultation with bedside patient evaluation. Studies in other patient groups (solid organ transplant recipients or intensive care unit patients) or in the context of other infections (infective endocarditis, pneumonia, other bloodstream infections) also revealed positive effects of ID consultations. Higher rates of appropriate empirical and targeted antimicrobial treatments and de-escalation strategies due to successful pathogen identification were documented. These modifications resulted in lower treatment costs and decreased antimicrobial resistance development. Although there are methodological limitations in single studies, we consider the consistent and reproducible positive effects of ID consultations shown in studies in different countries and health care systems as convincing evidence for improved quality-of-care and treatment outcomes in patients with infectious diseases. Thus, we strongly recommend efforts to establish significantly more ID consultation services in hospitals in Germany.
Literatur
1.
Zurück zum Zitat Bursle EC, Playford EG, Looke DF. Infectious diseases consultations at an Australian tertiary hospital: a review of 11,511 inpatient consultations. Intern Med J. 2014;44:998–1004.CrossRefPubMed Bursle EC, Playford EG, Looke DF. Infectious diseases consultations at an Australian tertiary hospital: a review of 11,511 inpatient consultations. Intern Med J. 2014;44:998–1004.CrossRefPubMed
2.
Zurück zum Zitat Kern WV. Management of Staphylococcus aureus bacteremia and endocarditis: progresses and challenges. Curr Opin Infect Dis. 2010;23:346–58.CrossRefPubMed Kern WV. Management of Staphylococcus aureus bacteremia and endocarditis: progresses and challenges. Curr Opin Infect Dis. 2010;23:346–58.CrossRefPubMed
3.
Zurück zum Zitat Bai AD, Showler A, Burry L, Steinberg M, Ricciuto DR, Fernandes T, et al. Impact of Infectious Disease Consultation on Quality of Care, Mortality, and Length of Stay in Staphylococcus aureus Bacteremia: results From a Large Multicenter Cohort Study. Clin Infect Dis. 2015;60:1451–61.PubMed Bai AD, Showler A, Burry L, Steinberg M, Ricciuto DR, Fernandes T, et al. Impact of Infectious Disease Consultation on Quality of Care, Mortality, and Length of Stay in Staphylococcus aureus Bacteremia: results From a Large Multicenter Cohort Study. Clin Infect Dis. 2015;60:1451–61.PubMed
4.
Zurück zum Zitat Honda H, Krauss MJ, Jones JC, Olsen MA, Warren DK. The value of infectious diseases consultation in Staphylococcus aureus bacteremia. Am J Med. 2010;123:631–7.CrossRefPubMedPubMedCentral Honda H, Krauss MJ, Jones JC, Olsen MA, Warren DK. The value of infectious diseases consultation in Staphylococcus aureus bacteremia. Am J Med. 2010;123:631–7.CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Lahey T, Shah R, Gittzus J, Schwartzman J, Kirkland K. Infectious diseases consultation lowers mortality from Staphylococcus aureus bacteremia. Medicine (Baltimore). 2009;88:263–7.CrossRef Lahey T, Shah R, Gittzus J, Schwartzman J, Kirkland K. Infectious diseases consultation lowers mortality from Staphylococcus aureus bacteremia. Medicine (Baltimore). 2009;88:263–7.CrossRef
6.
Zurück zum Zitat Lopez-Cortes LE, Del Toro MD, Galvez-Acebal J, Bereciartua-Bastarrica E, Farinas MC, Sanz-Franco M, et al. Impact of an evidence-based bundle intervention in the quality-of-care management and outcome of Staphylococcus aureus bacteremia. Clin Infect Dis. 2013;57:1225–33.CrossRefPubMed Lopez-Cortes LE, Del Toro MD, Galvez-Acebal J, Bereciartua-Bastarrica E, Farinas MC, Sanz-Franco M, et al. Impact of an evidence-based bundle intervention in the quality-of-care management and outcome of Staphylococcus aureus bacteremia. Clin Infect Dis. 2013;57:1225–33.CrossRefPubMed
7.
Zurück zum Zitat Nagao M, Iinuma Y, Saito T, Matsumura Y, Shirano M, Matsushima A, et al. Close cooperation between infectious disease physicians and attending physicians can result in better management and outcome for patients with Staphylococcus aureus bacteraemia. Clin Microbiol Infect. 2010;16:1783–8.CrossRefPubMed Nagao M, Iinuma Y, Saito T, Matsumura Y, Shirano M, Matsushima A, et al. Close cooperation between infectious disease physicians and attending physicians can result in better management and outcome for patients with Staphylococcus aureus bacteraemia. Clin Microbiol Infect. 2010;16:1783–8.CrossRefPubMed
8.
Zurück zum Zitat Rieg S, Peyerl-Hoffmann G, de With K, Theilacker C, Wagner D, Hubner J, et al. Mortality of S. aureus bacteremia and infectious diseases specialist consultation—a study of 521 patients in Germany. J Infect. 2009;59:232–9.CrossRefPubMed Rieg S, Peyerl-Hoffmann G, de With K, Theilacker C, Wagner D, Hubner J, et al. Mortality of S. aureus bacteremia and infectious diseases specialist consultation—a study of 521 patients in Germany. J Infect. 2009;59:232–9.CrossRefPubMed
9.
Zurück zum Zitat Robinson JO, Pozzi-Langhi S, Phillips M, Pearson JC, Christiansen KJ, Coombs GW, et al. Formal infectious diseases consultation is associated with decreased mortality in Staphylococcus aureus bacteraemia. Eur J Clin Microbiol Infect Dis. 2012;31:2421–8.CrossRefPubMed Robinson JO, Pozzi-Langhi S, Phillips M, Pearson JC, Christiansen KJ, Coombs GW, et al. Formal infectious diseases consultation is associated with decreased mortality in Staphylococcus aureus bacteraemia. Eur J Clin Microbiol Infect Dis. 2012;31:2421–8.CrossRefPubMed
10.
Zurück zum Zitat Saunderson RB, Gouliouris T, Nickerson EK, Cartwright EJ, Kidney A, Aliyu SH, et al. Impact of routine bedside infectious disease consultation on clinical management and outcome of Staphylococcus aureus bacteraemia in adults. Clin Microbiol Infect. 2015;21:779–85.CrossRefPubMedPubMedCentral Saunderson RB, Gouliouris T, Nickerson EK, Cartwright EJ, Kidney A, Aliyu SH, et al. Impact of routine bedside infectious disease consultation on clinical management and outcome of Staphylococcus aureus bacteraemia in adults. Clin Microbiol Infect. 2015;21:779–85.CrossRefPubMedPubMedCentral
11.
Zurück zum Zitat Vogel M, Schmitz RP, Hagel S, Pletz MW, Gagelmann N, Scherag A, et al. Infectious disease consultation for Staphylococcus aureus bacteremia - A systematic review and meta-analysis. J Infect. 2016;72:19–28.CrossRefPubMed Vogel M, Schmitz RP, Hagel S, Pletz MW, Gagelmann N, Scherag A, et al. Infectious disease consultation for Staphylococcus aureus bacteremia - A systematic review and meta-analysis. J Infect. 2016;72:19–28.CrossRefPubMed
12.
Zurück zum Zitat Isobe M, Uejima E, Seki M, Yamagishi Y, Miyawaki K, Yabuno K, et al. Methicillin-resistant Staphylococcus aureus bacteremia at a university hospital in Japan. J Infect Chemother. 2012;18:841–7.CrossRefPubMed Isobe M, Uejima E, Seki M, Yamagishi Y, Miyawaki K, Yabuno K, et al. Methicillin-resistant Staphylococcus aureus bacteremia at a university hospital in Japan. J Infect Chemother. 2012;18:841–7.CrossRefPubMed
13.
Zurück zum Zitat Tissot F, Calandra T, Prod’hom G, Taffe P, Zanetti G, Greub G, et al. Mandatory infectious diseases consultation for MRSA bacteremia is associated with reduced mortality. J Infect. 2014;69:226–34.CrossRefPubMed Tissot F, Calandra T, Prod’hom G, Taffe P, Zanetti G, Greub G, et al. Mandatory infectious diseases consultation for MRSA bacteremia is associated with reduced mortality. J Infect. 2014;69:226–34.CrossRefPubMed
15.
Zurück zum Zitat Forsblom E, Ruotsalainen E, Ollgren J, Jarvinen A. Telephone consultation cannot replace bedside infectious disease consultation in the management of Staphylococcus aureus Bacteremia. Clin Infect Dis. 2013;56:527–35.CrossRefPubMed Forsblom E, Ruotsalainen E, Ollgren J, Jarvinen A. Telephone consultation cannot replace bedside infectious disease consultation in the management of Staphylococcus aureus Bacteremia. Clin Infect Dis. 2013;56:527–35.CrossRefPubMed
16.
Zurück zum Zitat Kuo D, Gifford DR, Stein MD. Curbside consultation practices and attitudes among primary care physicians and medical subspecialists. JAMA. 1998;280:905–9.CrossRefPubMed Kuo D, Gifford DR, Stein MD. Curbside consultation practices and attitudes among primary care physicians and medical subspecialists. JAMA. 1998;280:905–9.CrossRefPubMed
17.
Zurück zum Zitat Pulcini C, Botelho-Nevers E, Dyar OJ, Harbarth S. The impact of infectious disease specialists on antibiotic prescribing in hospitals. Clin Microbiol Infect. 2014;20:963–72.CrossRefPubMed Pulcini C, Botelho-Nevers E, Dyar OJ, Harbarth S. The impact of infectious disease specialists on antibiotic prescribing in hospitals. Clin Microbiol Infect. 2014;20:963–72.CrossRefPubMed
18.
Zurück zum Zitat Classen DC, Burke JP, Wenzel RP. Infectious diseases consultation: impact on outcomes for hospitalized patients and results of a preliminary study. Clin Infect Dis. 1997;24:468–70.CrossRefPubMed Classen DC, Burke JP, Wenzel RP. Infectious diseases consultation: impact on outcomes for hospitalized patients and results of a preliminary study. Clin Infect Dis. 1997;24:468–70.CrossRefPubMed
19.
Zurück zum Zitat Hamandi B, Husain S, Humar A, Papadimitropoulos EA. Impact of infectious disease consultation on the clinical and economic outcomes of solid organ transplant recipients admitted for infectious complications. Clin Infect Dis. 2014;59:1074–82.CrossRefPubMed Hamandi B, Husain S, Humar A, Papadimitropoulos EA. Impact of infectious disease consultation on the clinical and economic outcomes of solid organ transplant recipients admitted for infectious complications. Clin Infect Dis. 2014;59:1074–82.CrossRefPubMed
20.
Zurück zum Zitat Schmitt S, McQuillen DP, Nahass R, Martinelli L, Rubin M, Schwebke K, et al. Infectious diseases specialty intervention is associated with decreased mortality and lower healthcare costs. Clin Infect Dis. 2014;58:22–8.CrossRefPubMed Schmitt S, McQuillen DP, Nahass R, Martinelli L, Rubin M, Schwebke K, et al. Infectious diseases specialty intervention is associated with decreased mortality and lower healthcare costs. Clin Infect Dis. 2014;58:22–8.CrossRefPubMed
21.
Zurück zum Zitat Kunin CM, Tupasi T, Craig WA. Use of antibiotics. A brief exposition of the problem and some tentative solutions. Ann Intern Med. 1973;79:555–60.CrossRefPubMed Kunin CM, Tupasi T, Craig WA. Use of antibiotics. A brief exposition of the problem and some tentative solutions. Ann Intern Med. 1973;79:555–60.CrossRefPubMed
22.
Zurück zum Zitat Fox BC, Imrey PB, Voights MB, Norwood S. Infectious disease consultation and microbiologic surveillance for intensive care unit trauma patients: a pilot study. Clin Infect Dis. 2001;33:1981–9.CrossRefPubMed Fox BC, Imrey PB, Voights MB, Norwood S. Infectious disease consultation and microbiologic surveillance for intensive care unit trauma patients: a pilot study. Clin Infect Dis. 2001;33:1981–9.CrossRefPubMed
23.
Zurück zum Zitat Raineri E, Pan A, Mondello P, Acquarolo A, Candiani A, Crema L. Role of the infectious diseases specialist consultant on the appropriateness of antimicrobial therapy prescription in an intensive care unit. Am J Infect Control. 2008;36:283–90.CrossRefPubMed Raineri E, Pan A, Mondello P, Acquarolo A, Candiani A, Crema L. Role of the infectious diseases specialist consultant on the appropriateness of antimicrobial therapy prescription in an intensive care unit. Am J Infect Control. 2008;36:283–90.CrossRefPubMed
24.
Zurück zum Zitat Farinas MC, Saravia G, Calvo-Montes J, Benito N, Martinez-Garde JJ, Farinas-Alvarez C, et al. Adherence to recommendations by infectious disease consultants and its influence on outcomes of intravenous antibiotic-treated hospitalized patients. BMC Infect Dis. 2012;12:292.CrossRefPubMedPubMedCentral Farinas MC, Saravia G, Calvo-Montes J, Benito N, Martinez-Garde JJ, Farinas-Alvarez C, et al. Adherence to recommendations by infectious disease consultants and its influence on outcomes of intravenous antibiotic-treated hospitalized patients. BMC Infect Dis. 2012;12:292.CrossRefPubMedPubMedCentral
25.
Zurück zum Zitat Yamamoto S, Hosokawa N, Sogi M, Inakaku M, Imoto K, Ohji G, et al. Impact of infectious diseases service consultation on diagnosis of infective endocarditis. Scand J Infect Dis. 2012;44:270–5.CrossRefPubMed Yamamoto S, Hosokawa N, Sogi M, Inakaku M, Imoto K, Ohji G, et al. Impact of infectious diseases service consultation on diagnosis of infective endocarditis. Scand J Infect Dis. 2012;44:270–5.CrossRefPubMed
26.
Zurück zum Zitat Lemmen SW, Hafner H, Kotterik S, Lutticken R, Topper R. Influence of an infectious disease service on antibiotic prescription behavior and selection of multiresistant pathogens. Infection. 2000;28:384–7.CrossRefPubMed Lemmen SW, Hafner H, Kotterik S, Lutticken R, Topper R. Influence of an infectious disease service on antibiotic prescription behavior and selection of multiresistant pathogens. Infection. 2000;28:384–7.CrossRefPubMed
27.
Zurück zum Zitat Lemmen SW, Becker G, Frank U, Daschner FD. Influence of an infectious disease consulting service on quality and costs of antibiotic prescriptions in a university hospital. Scand J Infect Dis. 2001;33:219–21.CrossRefPubMed Lemmen SW, Becker G, Frank U, Daschner FD. Influence of an infectious disease consulting service on quality and costs of antibiotic prescriptions in a university hospital. Scand J Infect Dis. 2001;33:219–21.CrossRefPubMed
28.
Zurück zum Zitat Gums JG, Yancey RW Jr, Hamilton CA, Kubilis PS. A randomized, prospective study measuring outcomes after antibiotic therapy intervention by a multidisciplinary consult team. Pharmacotherapy. 1999;19:1369–77.CrossRefPubMed Gums JG, Yancey RW Jr, Hamilton CA, Kubilis PS. A randomized, prospective study measuring outcomes after antibiotic therapy intervention by a multidisciplinary consult team. Pharmacotherapy. 1999;19:1369–77.CrossRefPubMed
29.
Zurück zum Zitat Retamar P, Portillo MM, Lopez-Prieto MD, Rodriguez-Lopez F, de Cueto M, Garcia MV, et al. Impact of inadequate empirical therapy on the mortality of patients with bloodstream infections: a propensity score-based analysis. Antimicrob Agents Chemother. 2012;56:472–8.CrossRefPubMedPubMedCentral Retamar P, Portillo MM, Lopez-Prieto MD, Rodriguez-Lopez F, de Cueto M, Garcia MV, et al. Impact of inadequate empirical therapy on the mortality of patients with bloodstream infections: a propensity score-based analysis. Antimicrob Agents Chemother. 2012;56:472–8.CrossRefPubMedPubMedCentral
30.
Zurück zum Zitat Marquet K, Liesenborgs A, Bergs J, Vleugels A, Claes N. Incidence and outcome of inappropriate in-hospital empiric antibiotics for severe infection: a systematic review and meta-analysis. Crit Care. 2015;19:63.CrossRefPubMedPubMedCentral Marquet K, Liesenborgs A, Bergs J, Vleugels A, Claes N. Incidence and outcome of inappropriate in-hospital empiric antibiotics for severe infection: a systematic review and meta-analysis. Crit Care. 2015;19:63.CrossRefPubMedPubMedCentral
31.
Zurück zum Zitat Garnacho-Montero J, Gutierrez-Pizarraya A, Escoresca-Ortega A, Corcia-Palomo Y, Fernandez-Delgado E, Herrera-Melero I, et al. De-escalation of empirical therapy is associated with lower mortality in patients with severe sepsis and septic shock. Intensive Care Med. 2014;40:32–40.CrossRefPubMed Garnacho-Montero J, Gutierrez-Pizarraya A, Escoresca-Ortega A, Corcia-Palomo Y, Fernandez-Delgado E, Herrera-Melero I, et al. De-escalation of empirical therapy is associated with lower mortality in patients with severe sepsis and septic shock. Intensive Care Med. 2014;40:32–40.CrossRefPubMed
32.
Zurück zum Zitat Leone M, Bechis C, Baumstarck K, Lefrant JY, Albanese J, Jaber S, et al. De-escalation versus continuation of empirical antimicrobial treatment in severe sepsis: a multicenter non-blinded randomized noninferiority trial. Intensive Care Med. 2014;40:1399–408.CrossRefPubMed Leone M, Bechis C, Baumstarck K, Lefrant JY, Albanese J, Jaber S, et al. De-escalation versus continuation of empirical antimicrobial treatment in severe sepsis: a multicenter non-blinded randomized noninferiority trial. Intensive Care Med. 2014;40:1399–408.CrossRefPubMed
33.
Zurück zum Zitat Singer C, Kaplan MH, Armstrong D. Bacteremia and fungemia complicating neoplastic disease. A study of 364 cases. Am J Med. 1977;62:731–42.CrossRefPubMed Singer C, Kaplan MH, Armstrong D. Bacteremia and fungemia complicating neoplastic disease. A study of 364 cases. Am J Med. 1977;62:731–42.CrossRefPubMed
34.
Zurück zum Zitat Farmakiotis D, Kyvernitakis A, Tarrand JJ, Kontoyiannis DP. Early initiation of appropriate treatment is associated with increased survival in cancer patients with Candida glabrata fungaemia: a potential benefit from infectious disease consultation. Clin Microbiol Infect. 2015;21:79–86.CrossRefPubMed Farmakiotis D, Kyvernitakis A, Tarrand JJ, Kontoyiannis DP. Early initiation of appropriate treatment is associated with increased survival in cancer patients with Candida glabrata fungaemia: a potential benefit from infectious disease consultation. Clin Microbiol Infect. 2015;21:79–86.CrossRefPubMed
35.
Zurück zum Zitat Patel M, Kunz DF, Trivedi VM, Jones MG, Moser SA, Baddley JW. Initial management of candidemia at an academic medical center: evaluation of the IDSA guidelines. Diagn Microbiol Infect Dis. 2005;52:29–34.CrossRefPubMed Patel M, Kunz DF, Trivedi VM, Jones MG, Moser SA, Baddley JW. Initial management of candidemia at an academic medical center: evaluation of the IDSA guidelines. Diagn Microbiol Infect Dis. 2005;52:29–34.CrossRefPubMed
36.
Zurück zum Zitat Takakura S, Fujihara N, Saito T, Kimoto T, Ito Y, Iinuma Y, et al. Improved clinical outcome of patients with Candida bloodstream infections through direct consultation by infectious diseases physicians in a Japanese university hospital. Infect Control Hosp Epidemiol. 2006;27:964–8.CrossRefPubMed Takakura S, Fujihara N, Saito T, Kimoto T, Ito Y, Iinuma Y, et al. Improved clinical outcome of patients with Candida bloodstream infections through direct consultation by infectious diseases physicians in a Japanese university hospital. Infect Control Hosp Epidemiol. 2006;27:964–8.CrossRefPubMed
37.
Zurück zum Zitat Sellier E, Labarere J, Gennai S, Bal G, Francois P, Pavese P. Compliance with recommendations and clinical outcomes for formal and informal infectious disease specialist consultations. Eur J Clin Microbiol Infect Dis. 2011;30:887–94.CrossRefPubMed Sellier E, Labarere J, Gennai S, Bal G, Francois P, Pavese P. Compliance with recommendations and clinical outcomes for formal and informal infectious disease specialist consultations. Eur J Clin Microbiol Infect Dis. 2011;30:887–94.CrossRefPubMed
38.
Zurück zum Zitat Vehreschild JJ, Morgen G, Cornely OA, Hartmann P, Koch S, Kalka-Moll W, et al. Evaluation of an infectious disease consultation programme in a German tertiary care hospital. Infection. 2013;41:1121–8.CrossRefPubMed Vehreschild JJ, Morgen G, Cornely OA, Hartmann P, Koch S, Kalka-Moll W, et al. Evaluation of an infectious disease consultation programme in a German tertiary care hospital. Infection. 2013;41:1121–8.CrossRefPubMed
39.
Zurück zum Zitat Pulcini C, Pradier C, Samat-Long C, Hyvernat H, Bernardin G, Ichai C, et al. Factors associated with adherence to infectious diseases advice in two intensive care units. J Antimicrob Chemother. 2006;57:546–50.CrossRefPubMed Pulcini C, Pradier C, Samat-Long C, Hyvernat H, Bernardin G, Ichai C, et al. Factors associated with adherence to infectious diseases advice in two intensive care units. J Antimicrob Chemother. 2006;57:546–50.CrossRefPubMed
40.
Zurück zum Zitat de La BA, Boutemy J, Thibon P, Michon J, Verdon R, Cattoir V. Clinical benefit of infectious diseases consultation: a monocentric prospective cohort study. Infection. 2012;40:501–7.CrossRef de La BA, Boutemy J, Thibon P, Michon J, Verdon R, Cattoir V. Clinical benefit of infectious diseases consultation: a monocentric prospective cohort study. Infection. 2012;40:501–7.CrossRef
41.
Zurück zum Zitat Rieg S, Kupper MF. Impact of an infectious diseases consultation service on the quality of care and the survival of patients with infectious diseases. Z Evid Fortbild Qual Gesundhwes. 2015;109:500–10.CrossRefPubMed Rieg S, Kupper MF. Impact of an infectious diseases consultation service on the quality of care and the survival of patients with infectious diseases. Z Evid Fortbild Qual Gesundhwes. 2015;109:500–10.CrossRefPubMed
42.
Zurück zum Zitat Gomez J, Conde Cavero SJ, Hernandez Cardona JL, Nunez ML, Ruiz GJ, Canteras M, et al. The influence of the opinion of an infectious disease consultant on the appropriateness of antibiotic treatment in a general hospital. J Antimicrob Chemother. 1996;38:309–14.CrossRefPubMed Gomez J, Conde Cavero SJ, Hernandez Cardona JL, Nunez ML, Ruiz GJ, Canteras M, et al. The influence of the opinion of an infectious disease consultant on the appropriateness of antibiotic treatment in a general hospital. J Antimicrob Chemother. 1996;38:309–14.CrossRefPubMed
43.
Zurück zum Zitat Byl B, Clevenbergh P, Jacobs F, Struelens MJ, Zech F, Kentos A, et al. Impact of infectious diseases specialists and microbiological data on the appropriateness of antimicrobial therapy for bacteremia. Clin Infect Dis. 1999;29:60–6.CrossRefPubMed Byl B, Clevenbergh P, Jacobs F, Struelens MJ, Zech F, Kentos A, et al. Impact of infectious diseases specialists and microbiological data on the appropriateness of antimicrobial therapy for bacteremia. Clin Infect Dis. 1999;29:60–6.CrossRefPubMed
44.
Zurück zum Zitat Fluckiger U, Zimmerli W, Sax H, Frei R, Widmer AF. Clinical impact of an infectious disease service on the management of bloodstream infection. Eur J Clin Microbiol Infect Dis. 2000;19:493–500.CrossRefPubMed Fluckiger U, Zimmerli W, Sax H, Frei R, Widmer AF. Clinical impact of an infectious disease service on the management of bloodstream infection. Eur J Clin Microbiol Infect Dis. 2000;19:493–500.CrossRefPubMed
45.
Zurück zum Zitat Eron LJ, Passos S. Early discharge of infected patients through appropriate antibiotic use. Arch Intern Med. 2001;161:61–5.CrossRefPubMed Eron LJ, Passos S. Early discharge of infected patients through appropriate antibiotic use. Arch Intern Med. 2001;161:61–5.CrossRefPubMed
46.
Zurück zum Zitat Kerremans JJ, Verbrugh HA, Vos MC. Frequency of microbiologically correct antibiotic therapy increased by infectious disease consultations and microbiological results. J Clin Microbiol. 2012;50:2066–8.CrossRefPubMedPubMedCentral Kerremans JJ, Verbrugh HA, Vos MC. Frequency of microbiologically correct antibiotic therapy increased by infectious disease consultations and microbiological results. J Clin Microbiol. 2012;50:2066–8.CrossRefPubMedPubMedCentral
47.
Zurück zum Zitat Apisarnthanarak A, Danchaivijitr S, Bailey TC, Fraser VJ. Inappropriate antibiotic use in a tertiary care center in Thailand: an incidence study and review of experience in Thailand. Infect Control Hosp Epidemiol. 2006;27:416–20.CrossRefPubMed Apisarnthanarak A, Danchaivijitr S, Bailey TC, Fraser VJ. Inappropriate antibiotic use in a tertiary care center in Thailand: an incidence study and review of experience in Thailand. Infect Control Hosp Epidemiol. 2006;27:416–20.CrossRefPubMed
48.
Zurück zum Zitat Kawanami GH, Fortaleza CM. Factors predictive of inappropriateness in requests for parenteral antimicrobials for therapeutic purposes: a study in a small teaching hospital in Brazil. Scand J Infect Dis. 2011;43:528–35.CrossRefPubMed Kawanami GH, Fortaleza CM. Factors predictive of inappropriateness in requests for parenteral antimicrobials for therapeutic purposes: a study in a small teaching hospital in Brazil. Scand J Infect Dis. 2011;43:528–35.CrossRefPubMed
49.
Zurück zum Zitat Hosoglu S, Parlak Z, Geyik MF, Palanci Y. Critical evaluation of antimicrobial use–a Turkish university hospital example. J Infect Dev Ctries. 2013;7:873–9.CrossRefPubMed Hosoglu S, Parlak Z, Geyik MF, Palanci Y. Critical evaluation of antimicrobial use–a Turkish university hospital example. J Infect Dev Ctries. 2013;7:873–9.CrossRefPubMed
50.
Zurück zum Zitat Bornard L, Dellamonica J, Hyvernat H, Girard-Pipau F, Molinari N, Sotto A, et al. Impact of an assisted reassessment of antibiotic therapies on the quality of prescriptions in an intensive care unit. Med Mal Infect. 2011;41:480–5.CrossRefPubMed Bornard L, Dellamonica J, Hyvernat H, Girard-Pipau F, Molinari N, Sotto A, et al. Impact of an assisted reassessment of antibiotic therapies on the quality of prescriptions in an intensive care unit. Med Mal Infect. 2011;41:480–5.CrossRefPubMed
51.
Zurück zum Zitat Lesprit P, Landelle C, Girou E, Brun-Buisson C. Reassessment of intravenous antibiotic therapy using a reminder or direct counselling. J Antimicrob Chemother. 2010;65:789–95.CrossRefPubMed Lesprit P, Landelle C, Girou E, Brun-Buisson C. Reassessment of intravenous antibiotic therapy using a reminder or direct counselling. J Antimicrob Chemother. 2010;65:789–95.CrossRefPubMed
52.
Zurück zum Zitat Rimawi RH, Mazer MA, Siraj DS, Gooch M, Cook PP. Impact of regular collaboration between infectious diseases and critical care practitioners on antimicrobial utilization and patient outcome. Crit Care Med. 2013;41:2099–107.CrossRefPubMed Rimawi RH, Mazer MA, Siraj DS, Gooch M, Cook PP. Impact of regular collaboration between infectious diseases and critical care practitioners on antimicrobial utilization and patient outcome. Crit Care Med. 2013;41:2099–107.CrossRefPubMed
Metadaten
Titel
Infectious diseases consultations can make the difference: a brief review and a plea for more infectious diseases specialists in Germany
verfasst von
Siegbert Rieg
Marc Fabian Küpper
Publikationsdatum
23.02.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Infection / Ausgabe 2/2016
Print ISSN: 0300-8126
Elektronische ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-016-0883-1

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