Skip to main content
main-content

29.10.2019 | Original Contribution

Insights into the Host Specificity of Mosquito-Borne Flaviviruses Infecting Wild Mammals

Zeitschrift:
EcoHealth
Autoren:
Jesús Sotomayor-Bonilla, María José Tolsá-García, Gabriel E. García-Peña, Diego Santiago-Alarcon, Hugo Mendoza, Paulina Alvarez-Mendizabal, Oscar Rico-Chávez, Rosa Elena Sarmiento-Silva, Gerardo Suzán
Wichtige Hinweise

Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1007/​s10393-019-01442-2) contains supplementary material, which is available to authorized users.

Abstract

Mosquito-borne flaviviruses (MBFVs) are of public and animal health concern because they cause millions of human deaths annually and impact domestic animals and wildlife globally. MBFVs are phylogenetically divided into two clades, one is transmitted by Aedes mosquitoes (Ae-MBFVs) associated with mammals and the other by Culex mosquitoes (Cx-MBFVs) associated with birds. However, this assumption has not been evaluated. Here, we synthesized 79 published reports of MBFVs from wild mammals, estimating their host. Then, we tested whether the host specificity was biased to sampling and investigation efforts or to phylogenetic relationships using a viral phylogenetic tree drawn from analyzing whole flavivirus genomes obtained in GenBank. We found in total 18 flaviviruses, nine related to Aedes spp. and nine to Culex spp. infecting 129 mammal species. Thus, this supports that vectors are transmitting MBFV across available host clades and that ornithophilic mosquitoes are readily infecting mammals. Although most of the mosquito species are generalists in their host-feeding preferences, we also found a certain degree of MBFV’s specificity, as most of them infect closely related mammal species. The present study integrates knowledge regarding MBFVs, and it may help to understand their transmission dynamics between viruses, vectors, and mammal hosts.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

★ PREMIUM-INHALT
e.Med Interdisziplinär

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf SpringerMedizin.de. Zusätzlich können Sie eine Zeitschrift Ihrer Wahl in gedruckter Form beziehen – ohne Aufpreis.

Zusatzmaterial
Supplementary material 1 (XLSX 115 kb)
10393_2019_1442_MOESM1_ESM.xlsx
Supplementary material 2 (DOCX 24 kb)
10393_2019_1442_MOESM2_ESM.docx
Supplementary material 3 (NEX 3 kb)
10393_2019_1442_MOESM3_ESM.nex
Supplementary material 4 (XLSX 20 kb)
10393_2019_1442_MOESM4_ESM.xlsx
Literatur
Über diesen Artikel