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European Archives of Paediatric Dentistry

Erschienen in:

01.08.2016 | Original Scientific Article

Intercomparison of salivary nitric oxide as a biomarker of dental caries risk between caries-active and caries-free children

verfasst von: Dr. M. Syed, Dr. V. Sachdev, Dr. R. Chopra

Erschienen in: European Archives of Paediatric Dentistry | Ausgabe 4/2016

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Abstract

Aim

To determine the efficacy of salivary nitric oxide as a biomarker for dental caries risk in children and to compare the salivary nitric oxide levels in caries-active and caries-free children.

Methods

One hundred children aged 6–12 years were selected and were divided into two groups according to DMFT index: as caries-free consisting of 50 individuals (DMFT/dmft = 0) and caries-active group (DMFT/dmft ≥3) consisting of 50 individuals. The saliva collected was estimated for nitric oxide level by Griess reaction method. Paired t test was used to correlate the difference of mean salivary nitric oxide levels between caries-active and caries-free groups.

Results

The mean level of nitric oxide in saliva of the control group was 581.3 ± 134.6 μg/mL and that of caries-active group was 335.4 ± 111.1 μg/mL, respectively. The mean salivary level of nitric oxide was higher in the caries-free group as compared with the caries-active group which was statistically significant (p = 0.000).

Conclusions

Salivary nitric oxide was higher in the caries-free group as compared to the caries-active group which suggests that increased production of nitric oxide in the oral cavity may contribute to lower caries incidence in children.

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Titel: Intercomparison of salivary nitric oxide as a biomarker of dental caries risk between caries-active and caries-free children
verfasst von: Dr. M. Syed
Dr. V. Sachdev
Dr. R. Chopra
Publikationsdatum: 01.08.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: European Archives of Paediatric Dentistry / Ausgabe 4/2016
Print ISSN: 1818-6300
Elektronische ISSN: 1996-9805
DOI: https://doi.org/10.1007/s40368-016-0234-z

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Intercomparison of salivary nitric oxide as a biomarker of dental caries risk between caries-active and caries-free children

Abstract