Erschienen in:
01.10.2010 | Editorial
Interleukin-6: a local pain trigger?
verfasst von:
Camilla I Svensson
Erschienen in:
Arthritis Research & Therapy
|
Ausgabe 5/2010
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Abstract
Pain management in conditions of chronic inflammation is a clinical challenge, and increasing our understanding of the mechanisms driving this type of pain is important. In the previous issue of Arthritis Research & Therapy, Boettger and colleagues examine the role of IL-6 in antigen-induced arthritis using the IL-6 neutralizing soluble glycoprotein 130 and link IL-6 to a pathophysiological role in the generation of pain, independent of the proinflammatory properties of IL-6. The findings presented in this study add to a growing body of evidence highlighting the role of IL-6 in the induction and maintenance of pain.