Skip to main content
Erschienen in: Indian Journal of Thoracic and Cardiovascular Surgery 4/2019

27.04.2019 | Original Article

Intermittent on-pump beating-heart coronary artery bypass grafting—a safer option

verfasst von: Sushil Kumar Singh, Sarvesh Kumar, Ved Prakash, Vijayant Devenraj, Vivek Tewarson

Erschienen in: Indian Journal of Thoracic and Cardiovascular Surgery | Ausgabe 4/2019

Einloggen, um Zugang zu erhalten

Abstract

Purpose

On-pump beating-heart coronary artery bypass grafting represents a merger of standard on and off-pump techniques and is thought to benefit patients by coupling the dual absence of cardioplegic arrest (conventional coronary surgery), with the hemodynamic instability during manipulation seen in off-pump surgery. However, the clinical benefits are still under discussion. We improvised on the standard on-pump beating-heart surgeries by introducing use of “intermittent” bypass as and when required.

Methods

This study involved 108 patients. “Intermittent” on-pump-beating heart coronary artery bypass grafting was done using suction stabilizer and placing aortic and venous cannula, electively in all patients (group 1) who were supported by pump intermittently (n = 54). Retrospective data of patients who underwent off-pump surgery electively by the same surgeon (group 2, n = 54) was collected.

Results

There was a significant advantage in the number of grafts performed for the lateral surface (circumflex branches) using the new technique compared to conventional technique (68vs22). Similarly, significant advantage was also noted in terms of total number of grafts along with shorter operating times. There were no mortalities in the new group compared to the off-pump group and blood loss was also lesser.

Conclusions

“Intermittent” on-pump coronary revascularization is a technically reliable method of coronary revascularization taking advantage of the off-pump and conventional on-pump techniques while considerably eliminating the disadvantages of both. It has shown its superiority in safety, number of grafts, blood loss, operating time and perioperative course.
Literatur
1.
Zurück zum Zitat Perrault LP, Menasche P, Peynet J, et al. On-pump, beating heart coronary artery operations in high risk patients: an acceptable trade-off. Ann Thorac Surg. 1997;64:1368–73.CrossRefPubMed Perrault LP, Menasche P, Peynet J, et al. On-pump, beating heart coronary artery operations in high risk patients: an acceptable trade-off. Ann Thorac Surg. 1997;64:1368–73.CrossRefPubMed
2.
Zurück zum Zitat Al-Ruzzeh S, Nakamura K, Athanasiou T, et al. Does off-pump coronary artery bypass (OPCAB) surgery improve the outcome in high-risk patients?: a comparative study of 1398 high risk patients. Eur J Cardiothorac Surg. 2003;23:50–5.CrossRefPubMed Al-Ruzzeh S, Nakamura K, Athanasiou T, et al. Does off-pump coronary artery bypass (OPCAB) surgery improve the outcome in high-risk patients?: a comparative study of 1398 high risk patients. Eur J Cardiothorac Surg. 2003;23:50–5.CrossRefPubMed
3.
Zurück zum Zitat Takagi H, Umemoto T. Worse long-term survival after off-pump than on-pump coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2014;148:1820–9.CrossRefPubMed Takagi H, Umemoto T. Worse long-term survival after off-pump than on-pump coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2014;148:1820–9.CrossRefPubMed
4.
Zurück zum Zitat Légaré JF, Buth KJ, Hirsch GM. Conversion to on pump from OPCAB is associated with increased mortality: results from a randomized controlled trial. Eur J Cardiothorac Surg. 2005;27:296–301.CrossRefPubMed Légaré JF, Buth KJ, Hirsch GM. Conversion to on pump from OPCAB is associated with increased mortality: results from a randomized controlled trial. Eur J Cardiothorac Surg. 2005;27:296–301.CrossRefPubMed
5.
Zurück zum Zitat Chaudhry UA, Harling L, Sepehripour AH, et al. Beating- heart versus conventional on-pump coronary artery bypass grafting: a meta-analysis of clinical outcomes. Ann Thorac Surg. 2015;100:2251–60.CrossRefPubMed Chaudhry UA, Harling L, Sepehripour AH, et al. Beating- heart versus conventional on-pump coronary artery bypass grafting: a meta-analysis of clinical outcomes. Ann Thorac Surg. 2015;100:2251–60.CrossRefPubMed
6.
Zurück zum Zitat Ueki C, Sakaguchi G, Akimoto T, Ohashi Y, Sato H. On-pump beating-heart technique is associated with lower morbidity and mortality following coronary artery bypass grafting: a meta-analysis. Eur J Cardiothorac Surg. 2016;50:813–21.CrossRefPubMed Ueki C, Sakaguchi G, Akimoto T, Ohashi Y, Sato H. On-pump beating-heart technique is associated with lower morbidity and mortality following coronary artery bypass grafting: a meta-analysis. Eur J Cardiothorac Surg. 2016;50:813–21.CrossRefPubMed
7.
Zurück zum Zitat Miyahara K, Matsuura A, Takemura H, et al. On-pump beating-heart coronary artery bypass grafting after acute myocardial infarction has lower mortality and morbidity. J Thorac Cardiovasc Surg. 2008;135:521–6.CrossRefPubMed Miyahara K, Matsuura A, Takemura H, et al. On-pump beating-heart coronary artery bypass grafting after acute myocardial infarction has lower mortality and morbidity. J Thorac Cardiovasc Surg. 2008;135:521–6.CrossRefPubMed
8.
Zurück zum Zitat Izumi Y, Magishi K, Ishikawa N, Kimura F. On-pump beating- heart coronary artery bypass grafting for acute myocardial infarction. Ann Thorac Surg. 2006;81:573–6.CrossRefPubMed Izumi Y, Magishi K, Ishikawa N, Kimura F. On-pump beating- heart coronary artery bypass grafting for acute myocardial infarction. Ann Thorac Surg. 2006;81:573–6.CrossRefPubMed
9.
Zurück zum Zitat Rastan AJ, Eckenstein JI, Hentschel B, et al. Emergency coronary artery bypass graft surgery for acute coronary syndrome: beating heart versus conventional cardioplegic cardiac arrest strategies. Circulation. 2006;114:I477–85.CrossRefPubMed Rastan AJ, Eckenstein JI, Hentschel B, et al. Emergency coronary artery bypass graft surgery for acute coronary syndrome: beating heart versus conventional cardioplegic cardiac arrest strategies. Circulation. 2006;114:I477–85.CrossRefPubMed
10.
Zurück zum Zitat Brown WR, Moody DM, Challa VR, Stump DA, Hammon JW. Longer duration of cardiopulmonary bypass is associated with greater numbers of cerebral microemboli. Stroke. 2000;31:707–13.CrossRefPubMed Brown WR, Moody DM, Challa VR, Stump DA, Hammon JW. Longer duration of cardiopulmonary bypass is associated with greater numbers of cerebral microemboli. Stroke. 2000;31:707–13.CrossRefPubMed
11.
Zurück zum Zitat Gould BL, Clayton PD, Jensen RL, Liddle HV. Association between early graft patency and late outcome for patients undergoing coronary artery bypass surgery. Circulation. 1984;69:569–76.CrossRefPubMed Gould BL, Clayton PD, Jensen RL, Liddle HV. Association between early graft patency and late outcome for patients undergoing coronary artery bypass surgery. Circulation. 1984;69:569–76.CrossRefPubMed
12.
Zurück zum Zitat Fitzgibbon GM, Kafka HP, Leach AJ, Keon WJ, Hooper GD, Burton JR. Coronary bypass graft fate and patient outcome: angiographic follow- up of 5,065 grafts related to survival and reoperation in 1,388 patients during 25 years. J Am Coll Cardiol. 1996;28:616–26.CrossRefPubMed Fitzgibbon GM, Kafka HP, Leach AJ, Keon WJ, Hooper GD, Burton JR. Coronary bypass graft fate and patient outcome: angiographic follow- up of 5,065 grafts related to survival and reoperation in 1,388 patients during 25 years. J Am Coll Cardiol. 1996;28:616–26.CrossRefPubMed
13.
Zurück zum Zitat Synnergren MJ, Ekroth R, Oden A, Rexius H, Wiklund L. Incomplete revascularization reduces survival benefit of coronary artery bypass grafting: role of off-pump surgery. J Thorac Cardiovasc Surg. 2008;136:29–36.CrossRefPubMed Synnergren MJ, Ekroth R, Oden A, Rexius H, Wiklund L. Incomplete revascularization reduces survival benefit of coronary artery bypass grafting: role of off-pump surgery. J Thorac Cardiovasc Surg. 2008;136:29–36.CrossRefPubMed
14.
Zurück zum Zitat Dayan V, Paganini JJ, Marichal A, Brusich D. On-pump beating/non-beating CABG in stable angina have similar outcomes. Braz J Cardiovasc Surg. 2018;33:183–8.CrossRefPubMedPubMedCentral Dayan V, Paganini JJ, Marichal A, Brusich D. On-pump beating/non-beating CABG in stable angina have similar outcomes. Braz J Cardiovasc Surg. 2018;33:183–8.CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Kim HJ, Oh YN, Ju MH, et al. On-pump beating heart versus conventional coronary artery bypass grafting: comparative study on early and long-term clinical outcomes. J Thorac Dis. 2018;10:2656–65.CrossRefPubMedPubMedCentral Kim HJ, Oh YN, Ju MH, et al. On-pump beating heart versus conventional coronary artery bypass grafting: comparative study on early and long-term clinical outcomes. J Thorac Dis. 2018;10:2656–65.CrossRefPubMedPubMedCentral
16.
Zurück zum Zitat Borowski A, Korb H. Myocardial infarction in coronary bypass surgery using on-pump, beating heart technique with pressure and volume-controlled coronary perfusion. J Card Surg. 2002;17:272–8.CrossRefPubMed Borowski A, Korb H. Myocardial infarction in coronary bypass surgery using on-pump, beating heart technique with pressure and volume-controlled coronary perfusion. J Card Surg. 2002;17:272–8.CrossRefPubMed
17.
Zurück zum Zitat Jones RH. Intraoperative crossover: the well-kept surgical secret to apparent surgical success. J Am Coll Cardiol. 2005;45:1529–31.CrossRefPubMed Jones RH. Intraoperative crossover: the well-kept surgical secret to apparent surgical success. J Am Coll Cardiol. 2005;45:1529–31.CrossRefPubMed
18.
Zurück zum Zitat Kapetanakis EI, Stamou SC, Dullum MK, et al. The impact of aortic manipulation on neurologic outcomes after coronary artery bypass surgery: a risk-adjusted study. Ann Thorac Surg. 2004;78:1564–71.CrossRefPubMed Kapetanakis EI, Stamou SC, Dullum MK, et al. The impact of aortic manipulation on neurologic outcomes after coronary artery bypass surgery: a risk-adjusted study. Ann Thorac Surg. 2004;78:1564–71.CrossRefPubMed
19.
Zurück zum Zitat Sergeant P, de Worm E, Meyns B, Wouters P. The challenge of departmental quality control in the re-engineering towards off-pump coronary artery bypass grafting. Eur J Cardiothorac Surg. 2001;20:538–43.CrossRefPubMed Sergeant P, de Worm E, Meyns B, Wouters P. The challenge of departmental quality control in the re-engineering towards off-pump coronary artery bypass grafting. Eur J Cardiothorac Surg. 2001;20:538–43.CrossRefPubMed
20.
Zurück zum Zitat Sepehripour AH, Chaudhry UA, Harling L, Athanasiou T. Off-pump or on-pump beating heart: which technique offers better outcomes following coronary revascularization? Interact Cardiovasc Thorac Surg. 2015;20:546–9.CrossRefPubMed Sepehripour AH, Chaudhry UA, Harling L, Athanasiou T. Off-pump or on-pump beating heart: which technique offers better outcomes following coronary revascularization? Interact Cardiovasc Thorac Surg. 2015;20:546–9.CrossRefPubMed
Metadaten
Titel
Intermittent on-pump beating-heart coronary artery bypass grafting—a safer option
verfasst von
Sushil Kumar Singh
Sarvesh Kumar
Ved Prakash
Vijayant Devenraj
Vivek Tewarson
Publikationsdatum
27.04.2019
Verlag
Springer Singapore
Erschienen in
Indian Journal of Thoracic and Cardiovascular Surgery / Ausgabe 4/2019
Print ISSN: 0970-9134
Elektronische ISSN: 0973-7723
DOI
https://doi.org/10.1007/s12055-019-00821-2

Weitere Artikel der Ausgabe 4/2019

Indian Journal of Thoracic and Cardiovascular Surgery 4/2019 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.