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International Journal of Clinical Oncology

International Journal of Clinical Oncology OnlineFirst articles

05.01.2019 | Original Article Open Access

mFOLFOX6 plus bevacizumab to treat liver-only metastases of colorectal cancer that are unsuitable for upfront resection (TRICC0808): a multicenter phase II trial comprising the final analysis for survival

The liver is a frequent site of metastases from colorectal cancer [ 1 – 3 ], and hepatectomy is the only curative treatment, with a 5-year survival rate of 40–60% [ 3 – 7 ]. However, only a minority of patients with liver metastases are initially …

05.01.2019 | Original Article

Does postoperative prophylactic irradiation of para-aortic lymph nodes reduce the risk of recurrence in uterine cervical cancer with positive pelvic lymph nodes?

Cervical cancer is a common malignancy among females worldwide. Mortality rates associated with uterine cervical cancer have declined due to the widespread use of cancer screening for the prevention and early detection of cervical cancer [ 1 ].

05.01.2019 | Original Article

Clinical significance of multiple gene detection with a 22-gene panel in formalin-fixed paraffin-embedded specimens of 207 colorectal cancer patients

Colorectal cancer (CRC) is the third most common cancer worldwide, with more than one million new cases diagnosed every year [ 1 ]. It is also the fourth most common cause of cancer-related death, with 700,000 deaths per year [ 1 ]. Due to its high …

03.01.2019 | Original Article Open Access

Clinical factors associated with the therapeutic outcome of chemotherapy in very elderly cancer patients

In Japan, the proportion of the total Japanese population aged over 75 years is estimated to exceed 25% by 2025 [ 1 ]. This implies that number of elderly cancer patients will continue increase year by year.

02.01.2019 | Original Article

Preoperative predictive factors focused on inflammation-, nutrition-, and muscle-status in patients with upper urinary tract urothelial carcinoma undergoing nephroureterectomy

Upper urinary tract urothelial carcinoma (UTUC) is relatively rare, representing only approximately 5–10% of UCs, but is an aggressive and malignant disease [ 1 , 2 ]. Patients with UTUCs that invade the muscle layer usually have a poor prognosis.

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