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International Journal of Clinical Oncology

International Journal of Clinical Oncology OnlineFirst articles

23.05.2018 | Original Article

Treatment outcomes of hypofractionated radiotherapy combined with temozolomide followed by bevacizumab salvage therapy in glioblastoma patients aged > 75 years

Glioblastoma (GBM) is the most common malignant brain tumor in adults and is frequently found in patients aged > 60 years [ 1 ]. Despite therapeutic advances, the median survival period in such cases is approximately 14–18 months [ 2 – 4 ]. In …

22.05.2018 | Original Article

A prospective feasibility study applying the ACOSOG Z0011 criteria to Japanese patients with early breast cancer undergoing breast-conserving surgery

Axillary lymph node metastasis in early stage breast cancer patients is still a major prognostic factor for disease-free (DFS) and overall (OS) survival, so it has a great influence on the decisions about treatment strategy [ 1 ]. Axillary lymph …

21.05.2018 | Original Article

How asymptomatic are early cancer patients of five organs based on registry data in Japan

There are primary and secondary cancer prevention policies to reduce cancer mortality. Primary prevention reduces the cancer incidence by improving lifestyle habits, such as smoking cessation [ 1 ], and secondary prevention consists of cancer …

21.05.2018 | Original Article

Comparison of efficacy and toxicity of second-line combination chemotherapy regimens in patients with advanced urothelial carcinoma

Cisplatin-based chemotherapy is regarded as the gold standard for treatment of patients with advanced or metastatic urothelial carcinoma (UC) [ 1 ]. The regimen of methotrexate, vinblastine, doxorubicin, and cisplatin (M-VAC) has been widely used …

19.05.2018 | Original Article

Genetic mutation analysis of the malignant transformation of sinonasal inverted papilloma by targeted amplicon sequencing

Sinonasal papilloma accounts for 0.4–4.7% of all nasal tumors and is histopathologically classified into three types: inverted papilloma (IP), exophytic papilloma and oncocytic papilloma [ 1 ]. IP represents the most commonly diagnosed subtype of …

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