nach oben

Erschienen in:

15.09.2017 | Review Article - Vascular

Intracerebral hemorrhage as a manifestation of cerebral hyperperfusion syndrome after carotid revascularization: systematic review and meta-analysis

verfasst von: Pedro Abreu, Jerina Nogueira, Filipe Brogueira Rodrigues, Ana Nascimento, Mariana Carvalho, Ana Marreiros, Hipólito Nzwalo

Erschienen in: Acta Neurochirurgica | Ausgabe 11/2017

Einloggen, um Zugang zu erhalten

Abstract

Background

Intracerebral hemorrhage (ICH) in the context of cerebral hyperperfusion syndrome (CHS) is an uncommon but potentially lethal complication after carotid revascularization for carotid occlusive disease. Information about its incidence, risk factors and fatality is scarce. Therefore, we aimed to perform a systematic review and meta-analysis focusing on the incidence, risk factors and outcomes of ICH in the context of CHS after carotid revascularization.

Methods

We searched the PubMed and EBSCO hosts for all studies published in English about CHS in the context of carotid revascularization. Two reviewers independently assessed each study for eligibility based on predefined criteria. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed, and the PROSPERO register was made (register no. CRD42016033190), including the pre-specified protocol.

Results

Forty-one studies involving 28,956 participants were deemed eligible and included in our analysis. The overall quality of the included studies was fair. The pooled frequency of ICH in the context of CHS was 38% (95% CI: 26% to 51%, I2 = 84%, 24 studies), and the pooled case fatality of ICH after CHS was 51% (95% CI: 32% to 71%, I2 = 77%, 17 studies). When comparing carotid angioplasty with stenting (CAS) with carotid endarterectomy (CEA), post-procedural ICH in the context of CHS was less frequent in CEA. ICH following CHS occurred less often in large series and was rare in asymptomatic patients. The most common risk factors were periprocedural hypertension and ipsilateral severe stenosis.

Conclusions

ICH as a manifestation of CHS is rare, more frequent after CAS and associated with poor prognosis. Periprocedural control of hypertension can reduce its occurrence.

Nur mit Berechtigung zugänglich

Abou-Chebl A, Yadav JS, Reginelli JP, Bajzer C, Bhatt D, Krieger DW (2004) Intracranial hemorrhage and hyperperfusion syndrome following carotid artery stenting. J Am Coll Cardiol 43:6CrossRef

Ascher E, Markevich N, Schutzer RW, Kallakuri S, Jacob T, Hingorani AP (2003) Cerebral hyperperfusion syndrome after carotid endarterectomy: predictive factors and hemodynamic changes. J Vasc Surg 37:9CrossRef

Benzel EC, Hoppens KD (1991) Factors associated with postoperative hypertension complicating carotid endarterectomy. Acta Neurochir 112:5

Bonaldi G, Aiazzi L, Baruzzi F, Biroli F, Facchinetti A, Fachinetti P, Lunghi A, Terraneo F (2005) Angioplasty and stenting of the cervical carotid bifurcation under filter protection: a prospective study in a series of 53 patients. J Neuroradiol 32(2):109–117

Borst GJ, Moll FL, Van de Pavoordt HD, Mauser HW, Kelder JC, Ackerstaff RG (2001) Stroke from carotid endarterectomy: when and how to reduce perioperative stroke rate? Eur J Vasc Endovasc Surg 21(6):484–489

Bradac O, Mohapl M, Kramar F, Netuka D, Ostry S, Charvat F, Lacman J, Benes V (2014) Carotid endarterectomy and carotid artery stenting: changing paradigm during 10 years in a high-volume centre. Acta Neurochir 156:8CrossRef

Brantley HP, Kiessling JL, Milteer HB Jr, Mendelsohn FO (2009) Hyperperfusion syndrome following carotid artery stenting: the largest single-operator series to date. J Invasive Cardiol 21(1):27–30

Buczek J, Karliński M, Kobayashi A, Bialek P, Czlonkowska A (2013) Hyperperfusion syndrome after carotid endarterectomy and carotid stenting. Cerebrovasc Dis 35(6):531–537

Coutts SB, Hill MD, Hu W (2003) Hyperperfusion syndrome: toward a stricter definition. Neurosurgery 53(5):1053–1058

10.

Dalman JE, Beenakkers IC, Moll FL, Leusink JA, Ackerstaff RG (1999) Transcranial doppler monitoring during carotid endarterectomy helps to identify patients at risk of postoperative hyperperfusion. Eur J Vasc Endovasc Surg 18(3):222–227

11.

Deruty R, Mottolese C, Pelissou-Guyotat I, Lapras C (1991) The carotid endarterectomy: experience with 260 cases and discussion of the indications. Acta Neurochir 112:7CrossRef

12.

Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Blaha MJ (2014) Heart disease and stroke statistics and 2014 update: a report from the American Heart Association. Circulation 129:28CrossRef

13.

Gosseti B, Martinelli O, Guerricchio R, Irace L, Benedetti-Valentini F (1997) Transcranial doppler in 178 patients before, during and after carotid endarterectomy. J Neuroimaging 7(4):213–216

14.

Gupta AK, Purkayastha S, Unnikrishnan M, Vattoth S, Krishnamoorthy T, Kesavadas C (2005) Hyperperfusion syndrome after supraaortic vessel interventions and bypass surgery. J Neuroradiol 32:7CrossRef

15.

National Institute of Health. Study quality assessment Tools [https://www.nhlbi.nih.gov/health-pro/guidelines/in-develop/cardiovascular-risk-reduction/tools] Last Updated April 2014

16.

Henderson RD, Phan TG, Piepgras DG, Wijdicks EFM (2001) Mechanisms of intracerebral hemorrhage after carotid endarterectomy. J Neurosurg 95:6

17.

Henry M, Gopalakrishnan L, Rjagopal S, Rath PC, Henry I, Hugel M (2005) Bilateral carotid angioplasty and stenting. Catheter Cardiovasc Interv 64:8CrossRef

18.

Hosoda K, Kawaguchi T, Shibata Y, Kamei M, Kidoguchi K, Koyama J, Fujita S, Tamaki N (2001) Cerebral vasoreactivity and internal carotid artery flow help to identify patients at risk for hyperperfusion after carotid endarterectomy. Stroke 32(7):1567–1573

19.

Iko M, Aikawa H, Go Y, Nakai K, Tsutsumi M, Yu I, Mizokami T, Sakamoto K, Inoue R, Mitsutake T, Eto A, Hanada H, Kazekawa K (2014) Treatment outcomes of carotid artery stenting with two types of distal protection filter device. Springerplus 3:7CrossRef

20.

Jansen C, Sprengers AM, Moll FL, Vermeulen FEE, Hamerlijnck RPHM, van Gijin J, Ackerstaff RGA (1994) Prediction of intracerebral hemorrhage after carotid endarterectomy by clinical criteria and intraoperative transcranial doppler monitoring: results of 233 operations. Eur J Vasc Surg 8(2):220–225

21.

Kablak-Ziembicka A, Przewlocki T, Pieniazek P, Musialek P, Motyl R, Moczulski Z, Tracz W (2006) Assessment of flow changes in the circle of Willis after stenting for severe internal carotid artery stenosis. J Endovasc Ther 13:10CrossRef

22.

Kaku Y, Yoshimura S, Kokuzawa J (2004) Factors predictive of cerebral hyperperfusion after carotid angioplasty and stent placement. AJNR Am J Neuroradiol 25(8):1403–1408

23.

Karapanayiotides T, Meuli R, Devuyst G, Piechowski-Jozwiak B, Dewarrat A, Ruchat P, Segesser LV, Bogousslavsky (2004) Postcarotid endarterectomy hyperperfusion or reperfusion syndrome. Stroke 36:7

24.

Katano H, Mase M, Sakurai K, Miyachi S, Yamada K (2012) Revaluation of collateral pathways as escape routes from hyperemia/hyperperfusion following surgical treatment for carotid stenosis. Acta Neurochir 154:12CrossRef

25.

Kayahara T, Takeda R, Kikkawa Y, Take Y, Kurita H (2015) Hyperperfusion syndrome after aneurysm surgery: a case report. Acta Neurochir 157:3CrossRef

26.

Khattar NK, Friedlander RM, Chaer RA, Avgerinos ED, Kretz ES, Balzer JR, Crammond DJ, Habeych MH, Thirumala PD (2016) Perioperative stroke after carotid endarterectomy: etiology and implications. Acta Neurochir 158:7CrossRef

27.

Kim DYK, Kim BM, Park H, Chung J (2012) Retinal hemorrhage as an initial sign of cerebral hyperperfusion syndrome after carotid stenting. Acta Neurochir 154:3

28.

Kozar S, Jeromel M (2014) Hyperperfusion and intracranial haemorrhage after carotid angioplasty with stenting—latest review. Signa Vitae 9:6CrossRef

29.

Lai Z, Liu B, Chen Y, Ni L, Liu C (2015) Prediction of cerebral hyperperfusion syndrome with velocity blood pressure index. Chin Med J 128:7CrossRef

30.

Li SM, Li D, Ling F, Miao ZR, Wang ML (2005) Carotid artery stenting: experience of a single Institute in China. Interv Neuroradiol 11:8CrossRef

31.

Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, Ionannidis JPA, Clarke M, Devereaux PJ, Kleijnen J, Moher D (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Ann Intern Med 151:30CrossRef

32.

Lieb M, Shah U, Hines GL (2012) Cerebral hyperperfusion syndrome after carotid intervention: a review. Cardiol Rev 20(2):84–89

33.

Luengo-Fernandez R, Gray AM, Bull L, Cuthbertson F, Rothwell PM (2013) Oxford vascular study. Quality of life after TIA and stroke: ten-year results of the oxford vascular study. Neurology 81:95CrossRef

34.

Maas MBK, Kwolek CJ, Hirsch JA, Jaff MR, Rordorf GA (2013) Clinical risk predictors for cerebral hyperperfusion syndrome after carotid endarterectomy. J Neurol Neurosurg Psychiatry 84:5CrossRef

35.

Macfarlane R, Moskowitz MA, Sakas DE, Tasdemiroglu E, Wei EP, Kontos HA (1991) The role of neuroeffector mechanisms in cerebral hyperperfusion syndromes. J Neurosurg 1991:11

36.

Magee TR, Davies AH, Baird RN, Horrocks M (1992) Transcranial Doppler measurement before and after carotid endarterectomy. J R Coll Surg Edinb 37:2

37.

McCabe D, Brown MM, Clifton A (1999) Fatal cerebral reperfusion hemorrhage after carotid stenting. Stroke 30:4CrossRef

38.

McDonald RJ, Cloft HJ, Kallmes DF (2011) Intracraneal hemorrhage is much more common after carotid stenting than after endarterectomy. Evidence from the national inpatient sample. Stroke 42(10):2782–2787

39.

Mohammadian R, Sohrabi B, Mansourizadeh R, Mohammadian F, Nasiri B, Haririan S (2012) Unprotected carotid artery stenting: complications in 6 months follow-up. J Neuroradiol 54:7CrossRef

40.

Morrish W, Grahovac S, Douen A, Cheung G, Hu W, Farb R, Kalapos P, Wee R, Hudon M, Agbi C, Richard M (2000) Intracranial hemorrhage after stenting and angioplasty of extracranial carotid stenosis. AJNR Am J Neuroradiol 21(10):1911–1916

41.

Moulakakis KG, Mylonas SN, Sfyroeras GS, Andrikopoulos V (2009) Hyperperfusion syndrome after carotid revascularization. J Vasc Surg 49:9CrossRef

42.

Narita S, Aikawa H, Nagata S, Tstutsumi M, Kouhei N, Yoshida H, Matsumoto Y, Hamaguchi S, Etoh H, Sakamoto K, Inoue R, Kazekawa K (2013) Intraprocedural prediction of hemorrhagic cerebral Hyperperfusion syndrome after carotid artery stenting. J Stroke Cerebrovasc Dis 22:5CrossRef

43.

Naylor AR, Evans J, Thompson MM, London NJM, Abbott RJ, Cherryman G, Bell PRF (2003) Seizures after carotid endarterectomy: hyperperfusion, dysautoregulation or hypertensive encephalopathy? Eur J Vasc Endovasc Surg 26:6

44.

Newman JE, Ali M, Sharpe R, Bown MJ, Sayers RD, Naylor AR (2013) Changes in middle cerebral artery velocity after carotid endarterectomy do not identify patients at high-risk of suffering intracranial haemorrhage or stroke due to hyperperfusion syndrome. Eur Soc Vasc Surg 45(6):562–571

45.

Nicholas GG, Hashemi H, Gee W, Reed JF (1993) The cerebral hyperperfusion syndrome: diagnostic value of ocular pneumoplethysmography. J Vasc Surg 17:6CrossRef

46.

Ogasawara K, Inoue T, Kobayashi M, Endo H, Yoshida K, Fukuda T, Terasaki K, Ogawa A (2005) Cerebral hyperperfusion following carotid endarterectomy: diagnostic utility of intraoperative transcranial Doppler ultrasonography compared with single-photon emission computed tomography study. AJNR Am J Neuroradiol 26(2):252–257

47.

Ogasawara K, Sakai N, Kuroiwa T, Hosoda K, Iihara K, Toyoda K, Sakai C, Nagata I, Ogawa A (2007) Intracranial hemorrhage associated with cerebral hyperperfusion syndrome following carotid endarterectomy and carotid artery stenting: retrospective review of 4494 patients. J Neurosurg 107(6):1130–1136

48.

Ogasawara K, Yukawa H, Kobayashi M et al (2003) Prediction and monitoring of cerebral hyperperfusion after carotid endarterectomy by using single-photon emission computerized tomography scanning. J Neurosurg 99:7CrossRef

49.

Pieniazek PT, Tekieli L, Musialek P, Kablak-Ziembicka A, Przewlocki T, Motyl R, Dzierwa K, Paluszek P, Hlawaty M, Zmudka K, Podolec P (2012) Carotid artery stenting according to the ‘tailored-CAS’ algorithm is associated with a low complication rate at 30 days: data from the TARGET-CAS study. Kardiol Pol 70:9

50.

Piepgras D, Morgan MK, Sundt T, Yanagiihara T, Mussman LM (1988) Intracerebral hemorrhage after carotid endarterectomy. J Neurosurg 68:5CrossRef

51.

Schroeder T, Sillesen H, Boesen J, Laursen H, Sorensen P (1987) Intracerebral hemorrhage after carotid endarterectomy. Eur J Vasc Surg 1(1):51–60

52.

Solomon RA, Loftus CM, Quest DO, Correll JW (1986) Incidence and etiology of intracerebral hemorrhage following carotid endarterectomy. J Neurosurg 64(1):29–34

53.

Sprigg NS, Selby J, Fox L, Berge E, Whynes D, Bath PM (2013) Efficacy of nitric oxide in stroke investigators. Very low quality of life after acute stroke: data from the efficacy of nitric oxide in stroke trial. Stroke 44:62CrossRef

54.

Sundt TM Jr, Sharbrough FW, Piepgras DG, Kearns TP, Messick JM Jr, O’Fallon WM (1981) Correlation of cerebral blood flow and electroencephalographic changes during carotid endarterectomy: with results of surgery and hemodynamics of cerebral ischemia. Mayo Clin Proc 56:11

55.

Tan GS, Phatouros CC (2009) Cerebral hyperperfusion syndrome post-carotid artery stenting. J Med Imaging Radiat Oncol 53:7CrossRef

56.

Terada T, Tsuura M, Matsumoto H, Masuo O, Tsumoto T, Yamaga H, Ohura Y, Itakura T (2006) Hemorrhagic complications after endovascular therapy for atherosclerotic intracranial arterial stenoses. Neurosurgery 59:9

57.

Tietke MW, Kerby T, Alfke K, Riedel C, Rohr A, Jensen U, Zimmermann P, Stingele R, Jansen O (2009) Complication rate in unprotected carotid artery stenting with closed-cell stents. Neuroradiology 52(7):611–618

58.

Timmers HJLM, Wieling W, Karemaker JM, Lenders JWM (2004) Baroreflex failure: a neglected type of secondary hypertension. Neth J Med 62:5

59.

Urbach DR (2005) Measuring quality of life after surgery. Surg Innov 12:5CrossRef

60.

van Mook WN, Rennenberg RJ, Schurink GW, van Oostenbrugge RJ, Mess WH, Hofman PAM, de Leeuw PW (2005) Cerebral hyperperfusion syndrome. Lancet Neurol 4:12CrossRef

61.

Wagner WH, Cossman DV, Farber A, Levin PM, Cohen JL (2005) Hyperperfusion syndrome after carotid endarterectomy. Ann Vasc Surg 19(4):479–486

62.

Wallaert JB, Nolan BW, Stone DH, Powell RJ, Brown JR, Cronenwett JL, Googney PP (2016) Physician specialty and variation in carotid revascularization technique selected for Medicare patients. J Vasc Surg 63:9CrossRef

63.

Wilson PV, Ammar AD (2005) The incidence of ischaemic stroke versus intracerebral hemorrhage after carotid endarterectomy: a review of 2452 cases. Ann Vasc Surg 19(1):1–4

64.

Wu YM, Wong HF, Chen Y-L, Wong M-C, Toh C-H (2011) Carotid stenting of asymptomatic and symptomatic carotid artery stenoses with and without the use of a distal embolic protection device. Acta Cardiol 66:6CrossRef

65.

Yoshie T, Ueda T, Takada T, Nogoshi S, Fukano T, Hasegawa Y (2016) Prediction of cerebral hyperperfusion syndrome after carotid artery stenting by CT perfusion imaging with acetazolamide challenge. Neuroradiology 58:7CrossRef

66.

Zhu CZ, Norris JW (1990) Role of carotid stenosis in ischemic stroke. Stroke 21:4CrossRef

Titel: Intracerebral hemorrhage as a manifestation of cerebral hyperperfusion syndrome after carotid revascularization: systematic review and meta-analysis
verfasst von: Pedro Abreu
Jerina Nogueira
Filipe Brogueira Rodrigues
Ana Nascimento
Mariana Carvalho
Ana Marreiros
Hipólito Nzwalo
Publikationsdatum: 15.09.2017
Verlag: Springer Vienna
Erschienen in: Acta Neurochirurgica / Ausgabe 11/2017
Print ISSN: 0001-6268
Elektronische ISSN: 0942-0940
DOI: https://doi.org/10.1007/s00701-017-3328-4

Leitlinien kompakt für die Neurologie

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Neurologie

Sind Frauen die fähigeren Ärzte?

30.04.2024 Gendermedizin Nachrichten

Patienten, die von Ärztinnen behandelt werden, dürfen offenbar auf bessere Therapieergebnisse hoffen als Patienten von Ärzten. Besonders gilt das offenbar für weibliche Kranke, wie eine Studie zeigt.

Akuter Schwindel: Wann lohnt sich eine MRT?

28.04.2024 Schwindel Nachrichten

Akuter Schwindel stellt oft eine diagnostische Herausforderung dar. Wie nützlich dabei eine MRT ist, hat eine Studie aus Finnland untersucht. Immerhin einer von sechs Patienten wurde mit akutem ischämischem Schlaganfall diagnostiziert.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Frühe Alzheimertherapie lohnt sich

25.04.2024 AAN-Jahrestagung 2024 Nachrichten

Ist die Tau-Last noch gering, scheint der Vorteil von Lecanemab besonders groß zu sein. Und beginnen Erkrankte verzögert mit der Behandlung, erreichen sie nicht mehr die kognitive Leistung wie bei einem früheren Start. Darauf deuten neue Analysen der Phase-3-Studie Clarity AD.

Update Neurologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

Abstract

Background

Methods

Results

Conclusions

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 11/2017

Timing of surgery for ruptured supratentorial arteriovenous malformations

Unruptured brain AVMs: it’s time we worked together to integrate care and clinical research

Deep brain stimulator infection by a novel rapid growing mycobacterium

Clinical characteristics of pituitary adenomas with radiological calcification

Long-term outcome after endovascular treatment of cavernous sinus dural arteriovenous fistula and a literature review