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01.04.2014 | R&D Insight Report

Ipragliflozin: First Global Approval

verfasst von: Raewyn M. Poole, Rosselle T. Dungo

Erschienen in: Drugs | Ausgabe 5/2014

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Abstract

Ipragliflozin (Suglat^® [Japan]), an orally active, next-generation sodium-glucose transporter 2 (SGLT2) inhibitor, has been developed by Astellas Pharma and Kotobuki Pharmaceutical for the treatment of type 2 diabetes mellitus. Ipragliflozin has received its first global approval in this indication in Japan, for use as monotherapy or in combination with another antihyperglycaemic agent (metformin, pioglitazone, a sulfonylurea, an α-glucosidase inhibitor, a dipeptidylpeptidase-4 inhibitor or nateglinide). Ipragliflozin is the first SGLT2 inhibitor to be approved in Japan. This article summarizes the milestones in the development of ipragliflozin leading to this first approval for the treatment of type 2 diabetes mellitus.

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Titel: Ipragliflozin: First Global Approval
verfasst von: Raewyn M. Poole
Rosselle T. Dungo
Publikationsdatum: 01.04.2014
Verlag: Springer International Publishing
Erschienen in: Drugs / Ausgabe 5/2014
Print ISSN: 0012-6667
Elektronische ISSN: 1179-1950
DOI: https://doi.org/10.1007/s40265-014-0204-x

Springer Medizin

Abstract

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