Erschienen in:
01.12.2009 | Letter to the editors
Irritability, psychomotor agitation and progressive insomnia induced by bilateral stimulation of the area surrounding the dorsal subthalamic nucleus (zona incerta) in Parkinson’s disease patients
verfasst von:
Marcelo Merello, Sol Cavanagh, Santiago Perez-Lloret, Eliana Roldan, Veronica Bruno, Eduardo Tenca, Ramon Leiguarda
Erschienen in:
Journal of Neurology
|
Ausgabe 12/2009
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Excerpt
It has been suggested that zona incerta (ZI) stimulation can have significant positive effect on motor signs, with comparable or even better results than STN stimulation [
11]. Unfortunately those reports lack cognitive and psychiatric evaluation, and no data on ZI-DBS effects of these domains, as well as on other non motor domains such as sleep, have been reported. We describe here two patients with Parkinson’s Disease (PD) suffering psychiatric complications, namely irritability, psychomotor agitation and severe progressive insomnia, as a consequence of bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN), also affecting the area surrounding the dorsal subthalamic nucleus including the ZI. …