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Erschienen in: European Spine Journal 1/2016

01.01.2016 | Original Article

Is smoking a risk factor for lumbar disc herniation?

verfasst von: Weimin Huang, Ying Qian, Kai Zheng, Lili Yu, Xiuchun Yu

Erschienen in: European Spine Journal | Ausgabe 1/2016

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Abstract

Purpose

To evaluate the association between cigarette smoking and lumbar disc herniation (LDH).

Methods

Cohort or case–control studies were identified by searches of several data bases, including Pubmed, Embase, Web of Science, and BIOSIS, for entries made up to December 2014. Data extraction was performed by two independent investigators. The data synthesis was performed using the random effects model. Subgroup analysis, sensitivity analyses, and assessment for publication bias were also performed.

Results

This systematic review included 12 studies—six each of cohort and case–control studies. The combined reported values showed that the relative risk of the association between smoking and LDH was 1.27 [95 % confidence interval (CI), 1.15–1.40] overall, 1.48 (95 % CI, 1.27–1.73) for case–control studies, and 1.17 (95 % CI, 1.05–1.30) for cohort studies.

Conclusion

This systematic review demonstrates that smoking promotes the development of LDH.
Literatur
1.
Zurück zum Zitat Rostron B (2013) Smoking-attributable mortality by cause in the United States: revising the CDC’s data and estimates. Nicotine Tob Res 15:238–246PubMedCrossRef Rostron B (2013) Smoking-attributable mortality by cause in the United States: revising the CDC’s data and estimates. Nicotine Tob Res 15:238–246PubMedCrossRef
2.
Zurück zum Zitat Schroeder SA (2014) Even more illness caused by smoking than previously estimated. JAMA Intern Med 174:1928–1929PubMedCrossRef Schroeder SA (2014) Even more illness caused by smoking than previously estimated. JAMA Intern Med 174:1928–1929PubMedCrossRef
3.
Zurück zum Zitat Jamal A, Agaku IT, O’Connor E, King BA, Kenemer JB, Neff L (2014) Current cigarette smoking among adults—United States, 2005–2013. MMWR Morb Mortal Wkly Rep 63:1108–1112PubMed Jamal A, Agaku IT, O’Connor E, King BA, Kenemer JB, Neff L (2014) Current cigarette smoking among adults—United States, 2005–2013. MMWR Morb Mortal Wkly Rep 63:1108–1112PubMed
4.
Zurück zum Zitat Rostron BL, Chang CM, Pechacek TF (2014) Estimation of cigarette smoking-attributable morbidity in the United States. JAMA Intern Med 174:1922–1928PubMedCrossRef Rostron BL, Chang CM, Pechacek TF (2014) Estimation of cigarette smoking-attributable morbidity in the United States. JAMA Intern Med 174:1922–1928PubMedCrossRef
5.
Zurück zum Zitat Hadjipavlou AG, Tzermiadianos MN, Bogduk N, Zindrick MR (2008) The pathophysiology of disc degeneration. J Bone Joint Surg Br 90B:1261–1270CrossRef Hadjipavlou AG, Tzermiadianos MN, Bogduk N, Zindrick MR (2008) The pathophysiology of disc degeneration. J Bone Joint Surg Br 90B:1261–1270CrossRef
6.
Zurück zum Zitat Nasto LA, Ngo K, Leme AS, Robinson AR, Dong Q, Roughley P, Usas A, Sowa GA, Pola E, Kang J, Niedernhofer LJ, Shapiro S, Vo NV (2014) Investigating the role of DNA damage in tobacco smoking-induced spine degeneration. Spine J 14:416–423PubMedPubMedCentralCrossRef Nasto LA, Ngo K, Leme AS, Robinson AR, Dong Q, Roughley P, Usas A, Sowa GA, Pola E, Kang J, Niedernhofer LJ, Shapiro S, Vo NV (2014) Investigating the role of DNA damage in tobacco smoking-induced spine degeneration. Spine J 14:416–423PubMedPubMedCentralCrossRef
7.
Zurück zum Zitat Leboeuf-Yde C (1999) Smoking and low back pain. A systematic literature review of 41 journal articles reporting 47 epidemiologic studies. Spine (Phila Pa 1976) 24:1463–1470CrossRef Leboeuf-Yde C (1999) Smoking and low back pain. A systematic literature review of 41 journal articles reporting 47 epidemiologic studies. Spine (Phila Pa 1976) 24:1463–1470CrossRef
8.
Zurück zum Zitat Zhang YG, Zhang F, Sun Z, Guo W, Liu J, Liu M, Guo X (2013) A controlled case study of the relationship between environmental risk factors and apoptotic gene polymorphism and lumbar disc herniation. Am J Pathol 182:56–63PubMedCrossRef Zhang YG, Zhang F, Sun Z, Guo W, Liu J, Liu M, Guo X (2013) A controlled case study of the relationship between environmental risk factors and apoptotic gene polymorphism and lumbar disc herniation. Am J Pathol 182:56–63PubMedCrossRef
9.
Zurück zum Zitat Wahlstrom J, Burstrom L, Nilsson T, Jarvholm B (2012) Risk factors for hospitalization due to lumbar disc disease. Spine (Phila Pa 1976) 37:1334–1339CrossRef Wahlstrom J, Burstrom L, Nilsson T, Jarvholm B (2012) Risk factors for hospitalization due to lumbar disc disease. Spine (Phila Pa 1976) 37:1334–1339CrossRef
10.
Zurück zum Zitat Sorensen IG, Jacobsen P, Gyntelberg F, Suadicani P (2011) Occupational and other predictors of herniated lumbar disc disease—a 33-year follow-up in the copenhagen male study. Spine 36:1541–1546PubMedCrossRef Sorensen IG, Jacobsen P, Gyntelberg F, Suadicani P (2011) Occupational and other predictors of herniated lumbar disc disease—a 33-year follow-up in the copenhagen male study. Spine 36:1541–1546PubMedCrossRef
11.
Zurück zum Zitat Schumann B, Bolm-Audorff U, Bergmann A, Ellegast R, Elsner G, Grifka J, Haerting J, Jager M, Michaelis M, Seidler A (2010) Lifestyle factors and lumbar disc disease: results of a German multi-center case-control study (EPILIFT). Arthritis Res Ther 12:R193PubMedPubMedCentralCrossRef Schumann B, Bolm-Audorff U, Bergmann A, Ellegast R, Elsner G, Grifka J, Haerting J, Jager M, Michaelis M, Seidler A (2010) Lifestyle factors and lumbar disc disease: results of a German multi-center case-control study (EPILIFT). Arthritis Res Ther 12:R193PubMedPubMedCentralCrossRef
12.
Zurück zum Zitat Saftic R, Grgic M, Ebling B (2006) Case-control study of risk factors for lumbar intervertebral disc herniation in Croatian Island populations. Croat Med J 47:593–600PubMedPubMedCentral Saftic R, Grgic M, Ebling B (2006) Case-control study of risk factors for lumbar intervertebral disc herniation in Croatian Island populations. Croat Med J 47:593–600PubMedPubMedCentral
13.
Zurück zum Zitat Rivinoja AE, Paananen MV, Taimela SP, Solovieva S, Okuloff A, Zitting P, Jarvelin MR, Leino-Arjas P, Karppinen JI (2011) Sports, smoking, and overweight during adolescence as predictors of sciatica in adulthood: a 28-year follow-up study of a birth cohort. Am J Epidemiol 173:890–897PubMedCrossRef Rivinoja AE, Paananen MV, Taimela SP, Solovieva S, Okuloff A, Zitting P, Jarvelin MR, Leino-Arjas P, Karppinen JI (2011) Sports, smoking, and overweight during adolescence as predictors of sciatica in adulthood: a 28-year follow-up study of a birth cohort. Am J Epidemiol 173:890–897PubMedCrossRef
14.
Zurück zum Zitat Lincoln AE, Smith GS, Amoroso PJ, Bell NS (2003) The effect of cigarette smoking on musculoskeletal-related disability. Am J Ind Med 43:337–349PubMedPubMedCentralCrossRef Lincoln AE, Smith GS, Amoroso PJ, Bell NS (2003) The effect of cigarette smoking on musculoskeletal-related disability. Am J Ind Med 43:337–349PubMedPubMedCentralCrossRef
15.
Zurück zum Zitat Kaila-Kangas L, Leino-Arjas P, Riihimaki H, Luukkonen R, Kirjonen J (2003) Smoking and overweight as predictors of hospitalization for back disorders. Spine (Phila Pa 1976) 28:1860–1868CrossRef Kaila-Kangas L, Leino-Arjas P, Riihimaki H, Luukkonen R, Kirjonen J (2003) Smoking and overweight as predictors of hospitalization for back disorders. Spine (Phila Pa 1976) 28:1860–1868CrossRef
16.
Zurück zum Zitat Jhawar BS, Fuchs CS, Colditz GA, Stampfer MJ (2006) Cardiovascular risk factors for physician-diagnosed lumbar disc herniation. Spine J 6:684–691PubMedCrossRef Jhawar BS, Fuchs CS, Colditz GA, Stampfer MJ (2006) Cardiovascular risk factors for physician-diagnosed lumbar disc herniation. Spine J 6:684–691PubMedCrossRef
17.
Zurück zum Zitat Colombini A, Brayda-Bruno M, Lombardi G, Croiset SJ, Vrech V, Maione V, Banfi G, Cauci S (2014) FokI Polymorphism in the vitamin D receptor gene (VDR) and its association with lumbar spine pathologies in the italian population: a case-control study. PLoS One 9:e97027PubMedPubMedCentralCrossRef Colombini A, Brayda-Bruno M, Lombardi G, Croiset SJ, Vrech V, Maione V, Banfi G, Cauci S (2014) FokI Polymorphism in the vitamin D receptor gene (VDR) and its association with lumbar spine pathologies in the italian population: a case-control study. PLoS One 9:e97027PubMedPubMedCentralCrossRef
18.
Zurück zum Zitat Chiang SL, Lin CH, Tsai SH, Chang ST, Lin SP, Ni SM, Wei SH, Wu YT, Lin FH, Chen LC (2014) Cigarette smoking dose as a predictor of need for surgical intervention in patients with lumbar disk herniation. J Med Sci (Taiwan) 34:23–29CrossRef Chiang SL, Lin CH, Tsai SH, Chang ST, Lin SP, Ni SM, Wei SH, Wu YT, Lin FH, Chen LC (2014) Cigarette smoking dose as a predictor of need for surgical intervention in patients with lumbar disk herniation. J Med Sci (Taiwan) 34:23–29CrossRef
19.
Zurück zum Zitat An HS, Silveri CP, Simpson JM, File P, Simmons C, Simeone FA, Balderston RA (1994) Comparison of smoking habits between patients with surgically confirmed herniated lumbar and cervical disc disease and controls. J Spinal Disord 7:369–373PubMed An HS, Silveri CP, Simpson JM, File P, Simmons C, Simeone FA, Balderston RA (1994) Comparison of smoking habits between patients with surgically confirmed herniated lumbar and cervical disc disease and controls. J Spinal Disord 7:369–373PubMed
20.
Zurück zum Zitat Zhang YG, Sun Z, Zhang Z, Liu J, Guo X (2009) Risk factors for lumbar intervertebral disc herniation in Chinese population: a case-control study. Spine (Phila Pa 1976) 34:E918–E922CrossRef Zhang YG, Sun Z, Zhang Z, Liu J, Guo X (2009) Risk factors for lumbar intervertebral disc herniation in Chinese population: a case-control study. Spine (Phila Pa 1976) 34:E918–E922CrossRef
21.
Zurück zum Zitat Younes M, Bejia I, Aguir Z, Letaief M, Hassen-Zrour S, Touzi M, Bergaoui N (2006) Prevalence and risk factors of disk-related sciatica in an urban population in Tunisia. Joint Bone Spine 73:538–542PubMedCrossRef Younes M, Bejia I, Aguir Z, Letaief M, Hassen-Zrour S, Touzi M, Bergaoui N (2006) Prevalence and risk factors of disk-related sciatica in an urban population in Tunisia. Joint Bone Spine 73:538–542PubMedCrossRef
24.
Zurück zum Zitat Ramstrom L, Wikmans T (2014) Mortality attributable to tobacco among men in Sweden and other European countries: an analysis of data in a WHO report. Tob Induc Dis 12:4CrossRef Ramstrom L, Wikmans T (2014) Mortality attributable to tobacco among men in Sweden and other European countries: an analysis of data in a WHO report. Tob Induc Dis 12:4CrossRef
25.
Zurück zum Zitat Lawrence RC, Felson DT, Helmick CG, Arnold LM, Choi H, Deyo RA, Gabriel S, Hirsch R, Hochberg MC, Hunder GG, Jordan JM, Katz JN, Kremers HM, Wolfe F, Natl Arthritis Data W (2008) Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Arthritis Rheum 58:26–35PubMedPubMedCentralCrossRef Lawrence RC, Felson DT, Helmick CG, Arnold LM, Choi H, Deyo RA, Gabriel S, Hirsch R, Hochberg MC, Hunder GG, Jordan JM, Katz JN, Kremers HM, Wolfe F, Natl Arthritis Data W (2008) Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Arthritis Rheum 58:26–35PubMedPubMedCentralCrossRef
26.
Zurück zum Zitat Freburger JK, Holmes GM, Agans RP, Jackman AM, Darter JD, Wallace AS, Castel LD, Kalsbeek WD, Carey TS (2009) The rising prevalence of chronic low back pain. Arch Inter Med 169:251–258CrossRef Freburger JK, Holmes GM, Agans RP, Jackman AM, Darter JD, Wallace AS, Castel LD, Kalsbeek WD, Carey TS (2009) The rising prevalence of chronic low back pain. Arch Inter Med 169:251–258CrossRef
28.
Zurück zum Zitat Kanayama M, Togawa D, Takahashi C, Terai T, Hashimoto T (2009) Cross-sectional magnetic resonance imaging study of lumbar disc degeneration in 200 healthy individuals: clinical article. J Neurosurg Spine 11:501–507PubMedCrossRef Kanayama M, Togawa D, Takahashi C, Terai T, Hashimoto T (2009) Cross-sectional magnetic resonance imaging study of lumbar disc degeneration in 200 healthy individuals: clinical article. J Neurosurg Spine 11:501–507PubMedCrossRef
29.
Zurück zum Zitat Karahan A, Kav S, Abbasoglu A, Dogan N (2009) Low back pain: prevalence and associated risk factors among hospital staff. J Adv Nurs 65:516–524PubMedCrossRef Karahan A, Kav S, Abbasoglu A, Dogan N (2009) Low back pain: prevalence and associated risk factors among hospital staff. J Adv Nurs 65:516–524PubMedCrossRef
30.
Zurück zum Zitat Leboeuf-Yde C, Yashin A, Lauritzen T (1996) Does smoking cause low back pain? Results from a population-based study. J Manip Physiol Ther 19:99–108 Leboeuf-Yde C, Yashin A, Lauritzen T (1996) Does smoking cause low back pain? Results from a population-based study. J Manip Physiol Ther 19:99–108
31.
Zurück zum Zitat Jones G, White C, Sambrook P, Eisman J (1998) Allelic variation in the vitamin D receptor, lifestyle factors and lumbar spinal degenerative disease. Ann Rheum Dis 57:94–99PubMedPubMedCentralCrossRef Jones G, White C, Sambrook P, Eisman J (1998) Allelic variation in the vitamin D receptor, lifestyle factors and lumbar spinal degenerative disease. Ann Rheum Dis 57:94–99PubMedPubMedCentralCrossRef
32.
Zurück zum Zitat Hangai M, Kaneoka K, Kuno S, Hinotsu S, Sakane M, Mamizuka N, Sakai S, Ochiai N (2008) Factors associated with lumbar intervertebral disc degeneration in the elderly. Spine J 8:732–740PubMedCrossRef Hangai M, Kaneoka K, Kuno S, Hinotsu S, Sakane M, Mamizuka N, Sakai S, Ochiai N (2008) Factors associated with lumbar intervertebral disc degeneration in the elderly. Spine J 8:732–740PubMedCrossRef
33.
34.
Zurück zum Zitat Karunanayake AL, Pathmeswaran A, Kasturiratne A, Wijeyaratne LS (2013) Risk factors for chronic low back pain in a sample of suburban Sri Lankan adult males. Int J Rheum Dis 16:203–210PubMedCrossRef Karunanayake AL, Pathmeswaran A, Kasturiratne A, Wijeyaratne LS (2013) Risk factors for chronic low back pain in a sample of suburban Sri Lankan adult males. Int J Rheum Dis 16:203–210PubMedCrossRef
35.
Zurück zum Zitat Lindal E, Stefansson JG (1996) Connection between smoking and back pain–findings from an Icelandic general population study. Scand J Rehabil Med 28:33–38PubMed Lindal E, Stefansson JG (1996) Connection between smoking and back pain–findings from an Icelandic general population study. Scand J Rehabil Med 28:33–38PubMed
36.
Zurück zum Zitat Manninen P, Riihimaki H, Heliovaara M (1995) Incidence and risk factors of low-back pain in middle-aged farmers. Occup Med 45:141–146CrossRef Manninen P, Riihimaki H, Heliovaara M (1995) Incidence and risk factors of low-back pain in middle-aged farmers. Occup Med 45:141–146CrossRef
37.
Zurück zum Zitat Mikkonen P, Leino-Arjas P, Remes J, Zitting P, Taimela S, Karppinen J (2008) Is smoking a risk factor for low back pain in adolescents? A prospective cohort study. Spine 33:527–532PubMedCrossRef Mikkonen P, Leino-Arjas P, Remes J, Zitting P, Taimela S, Karppinen J (2008) Is smoking a risk factor for low back pain in adolescents? A prospective cohort study. Spine 33:527–532PubMedCrossRef
38.
Zurück zum Zitat Miranda H, Viikari-Juntura E, Punnett L, Riihimaki H (2008) Occupational loading, health behavior and sleep disturbance as predictors of low-back pain. Scand J Work Environ Health 34:411–419PubMedCrossRef Miranda H, Viikari-Juntura E, Punnett L, Riihimaki H (2008) Occupational loading, health behavior and sleep disturbance as predictors of low-back pain. Scand J Work Environ Health 34:411–419PubMedCrossRef
39.
Zurück zum Zitat Zirbel SA, Stolworthy DK, Howell LL, Bowden AE (2013) Intervertebral disc degeneration alters lumbar spine segmental stiffness in all modes of loading under a compressive follower load. Spine J 13:1134–1147PubMedCrossRef Zirbel SA, Stolworthy DK, Howell LL, Bowden AE (2013) Intervertebral disc degeneration alters lumbar spine segmental stiffness in all modes of loading under a compressive follower load. Spine J 13:1134–1147PubMedCrossRef
40.
Zurück zum Zitat Iwahashi M, Matsuzaki H, Tokuhashi Y, Wakabayashi K, Uematsu Y (2002) Mechanism of intervertebral disc degeneration caused by nicotine in rabbits to explicate intervertebral disc disorders caused by smoking. Spine (Phila Pa 1976) 27:1396–1401CrossRef Iwahashi M, Matsuzaki H, Tokuhashi Y, Wakabayashi K, Uematsu Y (2002) Mechanism of intervertebral disc degeneration caused by nicotine in rabbits to explicate intervertebral disc disorders caused by smoking. Spine (Phila Pa 1976) 27:1396–1401CrossRef
41.
Zurück zum Zitat Nemoto Y, Matsuzaki H, Tokuhasi Y, Okawa A, Uematu Y, Nishimura T, Oda H (2006) Histological changes in intervertebral discs after smoking and cessation: experimental study using a rat passive smoking model. J Orthop Sci 11:191–197PubMedCrossRef Nemoto Y, Matsuzaki H, Tokuhasi Y, Okawa A, Uematu Y, Nishimura T, Oda H (2006) Histological changes in intervertebral discs after smoking and cessation: experimental study using a rat passive smoking model. J Orthop Sci 11:191–197PubMedCrossRef
42.
Zurück zum Zitat Higgins JPT GS (2011) Cochrane handbook for systematic reviews of interventions version 5.1.0 Higgins JPT GS (2011) Cochrane handbook for systematic reviews of interventions version 5.1.0
43.
Zurück zum Zitat Stang A (2010) Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol 25:603–605PubMedCrossRef Stang A (2010) Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol 25:603–605PubMedCrossRef
44.
Zurück zum Zitat Zhang J, Yu KF (1998) What’s the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes. JAMA 280:1690–1691PubMedCrossRef Zhang J, Yu KF (1998) What’s the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes. JAMA 280:1690–1691PubMedCrossRef
45.
Zurück zum Zitat Walker BF (2000) The prevalence of low back pain: a systematic review of the literature from 1966 to 1998. J Spinal Disord 13:205–217PubMedCrossRef Walker BF (2000) The prevalence of low back pain: a systematic review of the literature from 1966 to 1998. J Spinal Disord 13:205–217PubMedCrossRef
Metadaten
Titel
Is smoking a risk factor for lumbar disc herniation?
verfasst von
Weimin Huang
Ying Qian
Kai Zheng
Lili Yu
Xiuchun Yu
Publikationsdatum
01.01.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
European Spine Journal / Ausgabe 1/2016
Print ISSN: 0940-6719
Elektronische ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-015-4103-y

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