Anaplastic lymphoma kinase (ALK) gene fusions are rare in papillary thyroid carcinoma (PTC) but may serve as a therapeutic target. This study aims to evaluate the preoperative cytologic findings and clinicopathologic features of a series of eight …
In the last two decades, the increasing availability of technologies for molecular analyses has allowed an insight in the genomic alterations of neuroendocrine neoplasms (NEN) of the gastrointestinal tract and pancreas. This knowledge has …
A 33-year-old male was found to have a progressive right thyroid mass causing tracheal deviation and discomfort. His past medical history was remarkable for a gastric gastrointestinal stromal tumor (GIST) resected 10 years ago, with recurrent …
verfasst von:
Ozgur Mete, Mehmet Kefeli, Ralph Gilbert, Abha A. Gupta
Traditionally considered non-functional low proliferative benign neuroendocrine proliferations measuring less than 5 mm, pancreatic (neuro)endocrine microadenomas are now classified as pancreatic neuroendocrine microtumors in the 2022 WHO …
verfasst von:
Aziz Chouchane, Philipp Kirchner, Ilaria Marinoni, Eva Sticová, Tomáš Jirásek, Aurel Perren
Follicular thyroid carcinoma (FTC) is recognized by its ability to invade the tumor capsule and blood vessels, although the exact molecular signals orchestrating this phenotype remain elusive. In this study, the spatial transcriptional landscape …
verfasst von:
Vincenzo Condello, Johan O. Paulsson, Jan Zedenius, Anders Näsman, C. Christofer Juhlin
Digital pathology uses digitized images for cancer research. We aimed to assess morphometric parameters using digital pathology for predicting recurrence in patients with papillary thyroid carcinoma (PTC) and lateral cervical lymph node (LN) …
verfasst von:
Chae A Kim, Hyeong Rok An, Jungmin Yoo, Yu-Mi Lee, Tae-Yon Sung, Won Gu Kim, Dong Eun Song
