Indian Journal of Hematology and Blood Transfusion OnlineFirst articles

12.04.2024 | ORIGINAL ARTICLE

Prognostic Significance of T-Cells and Macrophages in the Tumour Microenvironment of Nodal DLBCL

Revised International Prognostic (R-IPI) score is used widely for risk stratification of DLBCL cases, yet some patients belonging to same risk category tend to exhibit different outcomes. The role of T-cells and macrophages in prognostication of …

verfasst von:: Soundarya Ravi, J. Sree Rekha, Debdatta Basu, Smita Kayal

11.04.2024 | ORIGINAL ARTICLE

MiR-34c-5p Inhibition Affects Bax/Bcl2 Expression and Reverses Bortezomib Resistance in Multiple Myeloma Cells

Developing resistance to anticancer drugs complicates the clinical treatment of multiple myeloma patients. Previous studies revealed a link between the unfolded protein response (UPR) and miRNAs with acquired drug resistance. This study aimed to …

verfasst von:: Emad Matour, Zari Tahannejad Asadi, Ahmad Ahmadzadeh Deilami, Seyed Saeed Azandeh, Behrouz Taheri

09.04.2024 | SHORT COMMUNICATION

Clinicopathological and Immunophenotypic Characteristics of Series of ZNF384 Re-arranged Acute Leukemias

Rearrangement involving ZNF384 gene (ZNF384-r) is recently being described in acute leukemias. We present the clinic-pathological and immunophenotypic findings in a series of five cases of acute leukemia with ZNF384-r reported in our Institute …

verfasst von:: Tharageswari Srinivasan, Praveen Sharma, Man Updesh Singh Sachdeva, Srinivasan Peyam, Lekshmon KS, Alka Khadwal, Sreejesh Sreedharanunni

08.04.2024 | IMAGES

Co-Infectious Mystery: Why Artemether-Lumefantrine Cleared P. falciparum but Left P. malariae behind

verfasst von:: Daniel Nunes, Filipa Luís, Maria Ana Quadros Flores, Carlos Ribeiro, Cristina Vaz Carneiro, José Melo Cristino

05.04.2024 | SHORT COMMUNICATION

Maternal and Foetal Outcomes of Newly Diagnosed Chronic Myeloid Leukemia During Pregnancy and its Long-Term Impact

Diagnosing Chronic Myeloid Leukemia (CML) during pregnancy presents challenges for both haematologists and obstetricians. Limited data exists regarding the management of pregnancy-associated CML in low- and middle-income countries (LMICs). This …

verfasst von:: Urmimala Bhattacharjee, Charanpreet Singh, Aditya Jandial, K. S. Lekshmon, Kundan Mishra, Rajeev Sandal, Ram Nampoothiri, Shano Naseem, Vanita Suri, Arihant Jain, Deepesh P. Lad, Gaurav Prakash, Alka Khadwal, Pankaj Malhotra

03.04.2024 | ORIGINAL ARTICLE

Application of Multi-Department Cooperation, Intelligent Prevention, and Supervision to Reduce the Incidence of Central Line-Associated Bloodstream Infections

Central line-associated bloodstream infections (CLABSIs) can result in worse outcomes and high hospitalization cost for patients. This study aimed to assess the effectiveness of multi-department cooperation, intelligent prevention, and supervision …

verfasst von:: Chuanfang Wu, Fan Dai, Donghua Yang, Xin You, Chuang Tan

02.04.2024 | CORRESPONDENCE

Ex-Vivo TCR αβ and CD19 Depleted Haploidentical Stem Cell Transplantation with CD45RO Memory T Cell Addback for CARD11 Deficiency

verfasst von:: Sandip Bartakke, Prasad Iyer

01.04.2024 | SHORT COMMUNICATION

A Brief Report on Pre-Transfusion Testing in Patients Receiving the Anti-CD38 Monoclonal Antibody for Hematological Disorders in India

The aim of this study is to analyze the profile of patients receiving daratumumab and their presentation to the transfusion laboratory by looking at the different pre-transfusion policies and the risk of erythrocyte alloimmunization. Patients …

verfasst von:: Durba Biswas, Debapriya Basu, Arijit Nag, Jeevan Kumar, Suvro Sankha Datta

01.04.2024 | CORRESPONDENCE

Palmoplantar Keratoderma in a Patient of Chronic Myeloid Leukemia on Dasatinib

verfasst von:: Priyansh Gupta, Priyanka Sangwan, Prabodha Kumar Das, Madhusmita Sethy, Biswanath Behera, Vishal Thakur

29.03.2024 | IMAGES

Osteosclerotic Myeloma: A rare encounter!

verfasst von:: Preeti Tripathi, Sanjeev Khera

25.03.2024 | SHORT COMMUNICATION

Prothrombin G20210A Mutation is Rare but not Absent Among North Indian Patients with Thromboembolic Events

Traditionally considered to be absent in India, prothrombin gene G20210A (NM_000506.5(F2): c.*97G > A) mutation (PGM) has recently been reported in few Indian patients. We aimed to assess the prevalence of PGM in patients with thromboembolic …

verfasst von:: Priti Satyarthi, Debadrita Ray, Vasant Kumar, Chander Hans, Hari Kishan Senee, Jasmina Ahluwalia, Reena Das, Arihant Jain, Kartik Vinay Mahesh, Narender Kumar

25.03.2024 | CORRESPONDENCE

Molecular Screening of VEL01N.01 and AUG02 Alleles in Indian Population: Towards Identifying Rare Blood Donors

verfasst von:: Harita Maru, Roshan Shaikh, Juili Narkar, Ajit Gorakshakar

25.03.2024 | ORIGINAL ARTICLE

Unmasking Infection Risks in Multiple Myeloma: Insights from a Retrospective Analysis

Multiple myeloma (MM) has witnessed significant therapeutic advancements through the introduction of proteasome inhibitors and immunomodulators, leading to improved treatment outcomes. However, infections remain a formidable challenge for MM …

verfasst von:: Linu Abraham Jacob, Sabeena K. Choudhary, M. C. Suresh Babu, Lokesh K N, A. H. Rudresha, L. K. Rajeev, Smitha C. Saldanha, Anup Hegde, Vivek B M

Open Access 25.03.2024 | ORIGINAL ARTICLE

Halofuginone Inhibits Osteoclastogenesis and Enhances Osteoblastogenesis by Regulating Th17/Treg Cell Balance in Multiple Myeloma Mice with Bone Lesions

Evidences shows that T helper 17 (Th17) and regulatory T (Treg) cells imbalance plays a critical role in bone lesions of MM patients. Therefore, regulating the Th17/Treg imbalance may be beneficial for bone lesions in MM. Ten MM mice complicated …

verfasst von:: Xiaofei Wu, Qiong Sun, Xiang Li, Lin Jiang, Li Chen

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25.03.2024 | ORIGINAL ARTICLE

Clinical Outcomes and Determinants of Survival in Patients with Hematologic Malignancies Admitted to Intensive Care Units with Critical Illness

Outcomes of patients with hematologic malignancies requiring ICU care for critical illness are suboptimal and represent a major unmet need in this population. We present data from a dedicated haematology oncology setting including 63 patients with …

verfasst von:: Suvir Singh, Rintu Sharma, Jagdeep Singh, Kunal Jain, Gurkirat Kaur, Vivek Gupta, P. L. Gautam

23.03.2024 | CORRESPONDENCE

CANCER Care in COVID-19 ERA: A Prospective Survey to Study the Preferences and Perspectives of Patients with Hematological Malignancies in a Tertiary Cancer Care Setting in India

verfasst von:: Surabhi Bhat, Avinash Bonda, Manju Sengar, Jayashree Thorat, Bhausaheb Bagal, Lingaraj Nayak, Jayita Deodhar, Karthik Rengaraj, Neha Sharma, Sadhana Kannan, Hemanth Muthuluri, Smruti Mokal, Thomas Eipe, Hasmukh Jain

22.03.2024 | CORRESPONDENCE

Successful Hematopoietic Stem Cell Transplantation in a Child with Thalassemia major and Moderate Haemophilia A

verfasst von:: Debranjani Chattopadhyay, Aby Abraham, Biju George

22.03.2024 | CORRESPONDENCE

Transient Spontaneous Remission of Acute Myeloid Leukemia with Mutated RUNX1: A Rare Report

verfasst von:: Xue Wu, Jingyuan Zhao, Yingying Chen, Zhihua Zhang, Xinhong Yang

20.03.2024 | SHORT COMMUNICATION

Granulocytapheresis Donor Deferrals Pattern at a Pediatric Tertiary Care Centre in Northern India

Granulocyte transfusion is used to manage refractory infections in patients with severe neutropenia. One of the main challenges in providing granulocyte products is the availability of a suitable donor. This study was designed to analyse deferral …

verfasst von:: Ruchika Bhartia, Seema Dua, R. Ganga, Satyam Arora

14.03.2024 | IMAGES

Microangiopathic Haemolytic Anaemia in Metastatic Angiosarcoma: A Grave Marker of Bone Marrow Infiltration

verfasst von:: Zachariah Thomas, Ajoy Oommen John, Thomas Alex Kodiatte, Ashish Singh

Springer Medizin