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Zeitschrift

Journal of Cancer Research and Clinical Oncology

Journal of Cancer Research and Clinical Oncology OnlineFirst articles

24.07.2021 | Original Article – Cancer Research Open Access

Treatment efficacy and safety of regorafenib plus drug-eluting beads-transarterial chemoembolization versus regorafenib monotherapy in colorectal cancer liver metastasis patients who fail standard treatment regimens

Colorectal cancer (CRC) is the third most common cancer that annually causes more than 14 million new CRC cases and over 8 million deaths worldwide (Ferlay 2015 ). Meanwhile, it is suggested that about 30–50% of CRC patients have developed …

24.07.2021 | Original Article – Cancer Research Open Access

Prognostic significance of high mobility group A2 (HMGA2) in pancreatic ductal adenocarcinoma: malignant functions of cytoplasmic HMGA2 expression

Effective treatment of patients with pancreatic ductal adenocarcinoma (PDAC) requires early diagnosis and intervention. Although considerable efforts have been made to identify underlying molecular mechanism and novel sensitive specific tumor …

23.07.2021 | Original Article – Clinical Oncology Open Access

Impact of induction chemotherapy with intermediate-dosed cytarabine and subsequent allogeneic stem cell transplantation on the outcome of high-risk acute myeloid leukemia

Incidence of secondary AML (s-AML) following myelodysplastic syndrome (MDS) is increasing with age and risk of transformation depends on stage of MDS as defined by percentage of blasts and genetic aberrations. Furthermore, AML with myeloid-related …

23.07.2021 | Original Article – Clinical Oncology

The efficacy of immune checkpoint inhibitors in advanced hepatocellular carcinoma: a meta-analysis based on 40 cohorts incorporating 3697 individuals

Hepatocellular carcinoma (HCC) is the third most frequent cause of cancer-related death all over the world with the incidence rising rapidly recently (Bray et al. 2018 ). The prognosis for patients with early stage HCC has been greatly improved …

22.07.2021 | Original Article – Cancer Research Open Access

Knockdown of the prognostic cancer stem cell marker Musashi-1 decreases radio-resistance while enhancing apoptosis in hormone receptor-positive breast cancer cells via p21WAF1/CIP1

Breast cancer remains the most common malignancy in women worldwide, thus carrying a significant burden of morbidity and mortality (Bray et al. 2018 ). Individual prognosis is mainly determined by the tumor’s metastatic ability and therapy …

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Über diese Zeitschrift

The "Journal of Cancer Research and Clinical Oncology" publishes significant and up-to-date articles within the fields of experimental and clinical oncology. The journal, which is chiefly devoted to Original papers and Rapid communications (given priority treatment by the Editors), also includes Reviews as well as Editorials and Guest editorials on current, controversial topics. The section Letters to the editors provides a forum for a rapid exchange of comments and information concerning previously published papers and topics of current interest. Meeting reports provide current information on the latest results presented at important congresses.

The following fields are covered: carcinogenesis - etiology, mechanisms; molecular biology; recent developments in tumor therapy; general diagnosis; laboratory diagnosis; diagnostic and experimental pathology; oncologic surgery; and epidemiology.

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