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Journal of Cancer Research and Clinical Oncology

Journal of Cancer Research and Clinical Oncology OnlineFirst articles

02.12.2020 | Original Article – Cancer Research Open Access

Treatment patterns and clinical outcomes in patients with advanced non-small cell lung cancer initiating first-line treatment in the US community oncology setting: a real-world retrospective observational study

The treatment landscape for advanced, unresectable, and/or metastatic non-small cell lung cancer (NSCLC) is evolving. Although doublet and triplet systemic chemotherapies were the mainstay treatment of advanced NSCLC for decades, limited …

26.11.2020 | Original Article – Clinical Oncology Open Access

Tumor suppression, dose-limiting toxicity and wellbeing with the fetal estrogen estetrol in patients with advanced breast cancer

Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer death in women (Bray et al. 2018 ), with metastatic disease accounting for the majority of deaths (Dillekas et al. 2019 ). In most women treated with …

25.11.2020 | Original Article – Cancer Research Open Access

Prognostic significance and therapeutic potential of the immune checkpoint VISTA in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is the most lethal type of human cancer, with a low 5-year survival rate of 6–10% (Yao et al. 2020 ). Recently, although programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 (PD-L1) blocking …

24.11.2020 | Review – Clinical Oncology Open Access

Risk of lung cancer and renin–angiotensin blockade: a concise review

The blockade of the renin–angiotensin–aldosterone system (RAAS) has immensely improved the treatment of patients with chronic arterial hypertension, acute myocardial infarction, chronic systolic heart failure, stroke, diabetic nephropathy and …

24.11.2020 | Original Article – Cancer Research Open Access

Mitochondrial DNA analysis efficiently contributes to the identification of metastatic contralateral breast cancers

Patients who experienced a breast neoplasia have a higher risk of developing a contralateral breast cancer (CBC) during their lifetime (Chen et al. 1999 ; Peralta et al. 2000 ; Goldstein et al. 2003 ; Raymond and Hogue 2006 ; Hartman et al. 2007 ).

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Über diese Zeitschrift

The "Journal of Cancer Research and Clinical Oncology" publishes significant and up-to-date articles within the fields of experimental and clinical oncology. The journal, which is chiefly devoted to Original papers and Rapid communications (given priority treatment by the Editors), also includes Reviews as well as Editorials and Guest editorials on current, controversial topics. The section Letters to the editors provides a forum for a rapid exchange of comments and information concerning previously published papers and topics of current interest. Meeting reports provide current information on the latest results presented at important congresses.

The following fields are covered: carcinogenesis - etiology, mechanisms; molecular biology; recent developments in tumor therapy; general diagnosis; laboratory diagnosis; diagnostic and experimental pathology; oncologic surgery; and epidemiology.

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