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Journal of Cancer Research and Clinical Oncology

Journal of Cancer Research and Clinical Oncology OnlineFirst articles

19.09.2018 | Original Article – Clinical Oncology

Everolimus in patients with multiply relapsed or cisplatin refractory germ cell tumors: results of a phase II, single-arm, open-label multicenter trial (RADIT) of the German Testicular Cancer Study Group

Most patients with metastatic germ cell cancer (GCC) can be cured with cisplatin-based chemotherapy, ranging from around 60% for poor prognosis patients to > 90% for good prognosis patients (IGCCCG 1997 ). Unfortunately, 20–30% of patients do not …

17.09.2018 | Original Article – Cancer Research

MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to FOXD1

Gliomas are tumors that arise from the brain or spine, which originated from glial progenitor or glial cells (Hosni-Ahmed et al. 2014 ; Mamelak and Jacoby 2007 ). It was reported that the incidence of gliomas was up to about 6–12 per 100,000 …

17.09.2018 | Original Article – Cancer Research

Presence and activity of HPV in primary lung cancer

Lung cancer leads the mortality ranking of death by cancer for both women and men and tobacco is the most common etiological factor (Torre et al. 2015 ; WHO 2017 ). However, many non-smokers, mainly women, were also diagnosed with this condition …

17.09.2018 | Original Article – Cancer Research

Circulating microRNA-99 family as liquid biopsy marker in pancreatic adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) moved from the fourth leading cause of cancer-related death in the USA and Europe to the third, surpassing breast cancer. While overall cancer incidence and death rates are declining worldwide, the incidence …

12.09.2018 | Review

Treatment outcomes of intracranial germinoma: a retrospective analysis of 170 patients from a single institution

Intracranial germ cell tumors are a rare malignant disease of the central nervous system and have a variety of histological classifications. Germinomas constitute approximately two-thirds of all intracranial germ cell tumors. The incidence of …

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Über diese Zeitschrift

The "Journal of Cancer Research and Clinical Oncology" publishes significant and up-to-date articles within the fields of experimental and clinical oncology. The journal, which is chiefly devoted to Original papers and Rapid communications (given priority treatment by the Editors), also includes Reviews as well as Editorials and Guest editorials on current, controversial topics. The section Letters to the editors provides a forum for a rapid exchange of comments and information concerning previously published papers and topics of current interest. Meeting reports provide current information on the latest results presented at important congresses.

The following fields are covered: carcinogenesis - etiology, mechanisms; molecular biology; recent developments in tumor therapy; general diagnosis; laboratory diagnosis; diagnostic and experimental pathology; oncologic surgery; and epidemiology.

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