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Journal of Cancer Research and Clinical Oncology

Journal of Cancer Research and Clinical Oncology OnlineFirst articles

16.06.2018 | Original Article – Clinical Oncology

Organized screening detects breast cancer at earlier stage regardless of molecular phenotype

Screening mammography has been widely implemented in developed countries (Weller et al. 2009 ). Perhaps, surprisingly, some controversy remains regarding its utility (Bleyer et al. 2016 ), particularly given the number needed to screen to prevent …

12.06.2018 | Original Article – Cancer Research

Cancer-associated fibroblasts promote gastric tumorigenesis through EphA2 activation in a ligand-independent manner

Erythropoietin-producing hepatocellular (Eph) receptors comprise the largest family of receptor tyrosine kinases, which play diverse roles in the regulation of cell–cell interactions such as differentiation, adhesion, migration, and death …

12.06.2018 | Original Article – Cancer Research

Association between pathologic factors and ERG expression in prostate cancer: finding pivotal networking

Recurrent gene fusions between the promoter of the transmembrane protease serine 2 gene ( TMPRSS2 ) and erythroblast (E-26) transformation-specific ( ETS ) family genes in prostate cancer have been recognized as a common and significant genomic …

11.06.2018 | Original Article – Cancer Research

Molecular classification and subtype-specific characterization of skin cutaneous melanoma by aggregating multiple genomic platform data

Skin melanoma, also known as cutaneous melanoma, is the most aggressive type of skin cancer. Despite great progress in biologic research and diagnostic approaches, the related morbidity and mortality rates have risen in all developed countries …

05.06.2018 | Original Article – Clinical Oncology

Trastuzumab-induced cardiotoxicity and its risk factors in real-world setting of breast cancer patients

The human epidermal growth factor 2 gene ( HER2 ) is amplified in ~ 20% of breast cancers. It was earlier associated with an increased relapse rate in localized disease and shorter overall survival in metastatic disease (Slamon et al. 1989 , 1987 …

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The "Journal of Cancer Research and Clinical Oncology" publishes significant and up-to-date articles within the fields of experimental and clinical oncology. The journal, which is chiefly devoted to Original papers and Rapid communications (given priority treatment by the Editors), also includes Reviews as well as Editorials and Guest editorials on current, controversial topics. The section Letters to the editors provides a forum for a rapid exchange of comments and information concerning previously published papers and topics of current interest. Meeting reports provide current information on the latest results presented at important congresses.

The following fields are covered: carcinogenesis - etiology, mechanisms; molecular biology; recent developments in tumor therapy; general diagnosis; laboratory diagnosis; diagnostic and experimental pathology; oncologic surgery; and epidemiology.

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