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Journal of Cancer Research and Clinical Oncology

Journal of Cancer Research and Clinical Oncology OnlineFirst articles

02.08.2020 | Original Article – Cancer Research

Prognostic value of TP53 co-mutation status combined with EGFR mutation in patients with lung adenocarcinoma

In the past decade, epidermal growth factor receptor tyrosine kinase inhibitors (TKIs) have turned into an important option for the treatment of lung adenocarcinoma (luad), showing higher objective response rate (ORR) and longer progression free …

30.07.2020 | Original Article – Clinical Oncology

Patterns of failure after adjuvant “sandwich” chemo-radio-chemotherapy in locally advanced (stage III–IVA) endometrial cancer

Endometrial cancer is the most common gynecological cancer in developed countries, with a lifetime risk of 2.8%. It is estimated that more than 55,000 newly diagnosed endometrial cancer are diagnosed every year in the United States. Over the last …

29.07.2020 | Original Article – Clinical Oncology

Risk stratification of postoperative recurrence in hypopharyngeal squamous-cell carcinoma patients with nodal metastasis

Although hypopharyngeal squamous-cell carcinoma (HPSCC) is rare and accounts for less than 5% of all head and neck squamous-cell carcinomas (HNSCC) (Bray et al. 2018 ), the prognosis of HPSCC is one of the worst in all HNSCC with a 5-year overall …

28.07.2020 | Review – Cancer Research

Effects of alpha-fetoprotein on the occurrence and progression of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world. Alpha-fetoprotein (AFP) is considered as a diagnostic and prognostic tumorous marker for HCC, and up to 70% of HCC patients showed elevated serum levels of …

28.07.2020 | Original Article – Cancer Research Open Access

Lysine-specific histone demethylase 1A (LSD1) in cervical cancer

Cervical cancer is with about 570,000 new cases in the year 2018, the fourth most frequent cancer after breast, colorectum and lung carcinoma in women worldwide. It represents about 6.6% of all female cancers. About 311,000 deaths occurred in 2018 …

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The "Journal of Cancer Research and Clinical Oncology" publishes significant and up-to-date articles within the fields of experimental and clinical oncology. The journal, which is chiefly devoted to Original papers and Rapid communications (given priority treatment by the Editors), also includes Reviews as well as Editorials and Guest editorials on current, controversial topics. The section Letters to the editors provides a forum for a rapid exchange of comments and information concerning previously published papers and topics of current interest. Meeting reports provide current information on the latest results presented at important congresses.

The following fields are covered: carcinogenesis - etiology, mechanisms; molecular biology; recent developments in tumor therapy; general diagnosis; laboratory diagnosis; diagnostic and experimental pathology; oncologic surgery; and epidemiology.

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