Skip to main content
Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy 11/2017

21.06.2016 | Knee

Kinesiophobia and depression affect total knee arthroplasty outcome in a multivariate analysis of psychological and physical factors on 200 patients

verfasst von: G. Filardo, G. Merli, A. Roffi, T. Marcacci, F. Berti Ceroni, D. Raboni, B. Bortolotti, E. Kon, M. Marcacci

Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy | Ausgabe 11/2017

Einloggen, um Zugang zu erhalten

Abstract

Purpose

To evaluate the effects of kinesiophobia on the outcomes of total knee arthroplasty (TKA), and to investigate whether kinesiophobia represents an independent factor influencing the surgery success or whether the observed effects are driven by other physical or psychological aspects such as anxiety and depression.

Methods

Two hundred patients were evaluated prospectively (mean age 65.7 ± 9.1 years, 134 women and 66 men) at 12 months after TKA. Kinesiophobia was assessed with the Tampa Scale for kinesiophobia (TSK: Activity Avoidance—TSK1 and Harm—TSK2 subscales); anxiety and depression were assessed with STAI and BDI, respectively, and preoperative pain and function, sex, age, BMI, education level, number of painful joints and years of symptoms’ duration before surgery were documented as well. Results were evaluated with pain and function on 0–10 numeric rating scales, while the overall clinical outcome was documented with WOMAC and SF-12 (Physical and Mental subscales) scores.

Results

TSK1 was correlated with WOMAC results at 12 months (p = 0.005, ρ = 0.197). STAI (p = 0.002, ρ = 0.222), BDI (p < 0.0005, ρ = 0.307), and sex (p = 0.004) also influenced the outcome after TKA, while other parameters, such as age, BMI, education level, and number of painful joints and years of symptoms’ duration before surgery, did not correlate with the clinical outcome. The multivariate analysis confirmed the role of BDI (p = 0.006, partial η 2 = 0.038), TSK1 (p = 0.011, partial η 2 = 0.033), and sex (p = 0.048, partial η 2 = 0.020), and a synergic interaction of BDI and TSK1, which together presented an even stronger correlation (p < 0.0005, partial η 2 = 0.111) with WOMAC at 12-month follow-up.

Conclusions

Kinesiophobia is a factor influencing the outcome after TKA independently from other psychological and physical variables. This risk factor may affect TKA results, especially in women, and shows a further synergic interaction with depression in terms of lower surgical outcome. These findings are of clinical relevance because they show the impact of psychological factors such as kinesiophobia, and suggest the possibility of adopting co-interventions to overcome the fear of physical activity, and in the end improve patient recovery and final outcome after TKA.

Level of evidence

IV.
Literatur
1.
Zurück zum Zitat Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW (1988) Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol 15(12):1833–1840PubMed Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW (1988) Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol 15(12):1833–1840PubMed
2.
Zurück zum Zitat Bonnin MP, Basiglini L, Archbold HA (2011) What are the factors of residual pain after uncomplicated TKA? Knee Surg Sports Traumatol Arthrosc 19(9):1411–1417CrossRefPubMed Bonnin MP, Basiglini L, Archbold HA (2011) What are the factors of residual pain after uncomplicated TKA? Knee Surg Sports Traumatol Arthrosc 19(9):1411–1417CrossRefPubMed
3.
Zurück zum Zitat Brander V, Gondek S, Martin E, Stulberg SD (2007) Pain and depression influence outcome 5 years after knee replacement surgery. Clin Orthop Relat Res 464:21–26PubMed Brander V, Gondek S, Martin E, Stulberg SD (2007) Pain and depression influence outcome 5 years after knee replacement surgery. Clin Orthop Relat Res 464:21–26PubMed
4.
Zurück zum Zitat Brander VA, Stulberg SD, Adams AD, Harden RN, Bruehl S, Stanos SP, Houle T (2003) Predicting total knee replacement pain: a prospective, observational study. Clin Orthop Relat Res 416:27–36CrossRef Brander VA, Stulberg SD, Adams AD, Harden RN, Bruehl S, Stanos SP, Houle T (2003) Predicting total knee replacement pain: a prospective, observational study. Clin Orthop Relat Res 416:27–36CrossRef
5.
Zurück zum Zitat Brown ML, Plate JF, Von Thaer S, Fino NF, Smith BP, Seyler TM, Lang JE (2016) Decreased range of motion after total knee arthroplasty is predicted by the Tampa Scale of Kinesiophobia. J Arthroplasty 31(4):793–797CrossRefPubMed Brown ML, Plate JF, Von Thaer S, Fino NF, Smith BP, Seyler TM, Lang JE (2016) Decreased range of motion after total knee arthroplasty is predicted by the Tampa Scale of Kinesiophobia. J Arthroplasty 31(4):793–797CrossRefPubMed
6.
Zurück zum Zitat Burns LC, Ritvo SE, Ferguson MK, Clarke H, Seltzer Z, Katz J (2015) Pain catastrophizing as a risk factor for chronic pain after total knee arthroplasty: a systematic review. J Pain Res 5(8):21–32 Burns LC, Ritvo SE, Ferguson MK, Clarke H, Seltzer Z, Katz J (2015) Pain catastrophizing as a risk factor for chronic pain after total knee arthroplasty: a systematic review. J Pain Res 5(8):21–32
7.
Zurück zum Zitat Doménech J, Sanchis-Alfonso V, Espejo B (2014) Changes in catastrophizing and kinesiophobia are predictive of changes in disability and pain after treatment in patients with anterior knee pain. Knee Surg Sports Traumatol Arthrosc 22(10):2295–2300CrossRefPubMed Doménech J, Sanchis-Alfonso V, Espejo B (2014) Changes in catastrophizing and kinesiophobia are predictive of changes in disability and pain after treatment in patients with anterior knee pain. Knee Surg Sports Traumatol Arthrosc 22(10):2295–2300CrossRefPubMed
8.
Zurück zum Zitat Dominick GM, Zeni JA, White DK (2016) The association of psychosocial factors with physical activity and function after total knee replacement: an exploratory study. Arch Phys Med Rehabil. doi:10.1016/j.apmr.2015.09.028 Dominick GM, Zeni JA, White DK (2016) The association of psychosocial factors with physical activity and function after total knee replacement: an exploratory study. Arch Phys Med Rehabil. doi:10.​1016/​j.​apmr.​2015.​09.​028
9.
Zurück zum Zitat Doury-Panchout F, Metivier JC, Fouquet B (2015) Kinesiophobia negatively influences recovery of joint function following total knee arthroplasty. Eur J Phys Rehabil Med 51(2):155–161PubMed Doury-Panchout F, Metivier JC, Fouquet B (2015) Kinesiophobia negatively influences recovery of joint function following total knee arthroplasty. Eur J Phys Rehabil Med 51(2):155–161PubMed
10.
Zurück zum Zitat Duivenvoorden T, Vissers MM, Verhaar JA, Busschbach JJ, Gosens T, Bloem RM, Bierma-Zeinstra SM, Reijman M (2013) Anxiety and depressive symptoms before and after total hip and knee arthroplasty: a prospective multicentre study. Osteoarthr Cartil 21(12):1834–1840CrossRefPubMed Duivenvoorden T, Vissers MM, Verhaar JA, Busschbach JJ, Gosens T, Bloem RM, Bierma-Zeinstra SM, Reijman M (2013) Anxiety and depressive symptoms before and after total hip and knee arthroplasty: a prospective multicentre study. Osteoarthr Cartil 21(12):1834–1840CrossRefPubMed
11.
Zurück zum Zitat Edwards RR, Bingham CO 3rd, Bathon J, Haythornthwaite JA (2006) Catastrophizing and pain in arthritis, fibromyalgia, and other rheumatic diseases. Arthritis Rheum 55(2):325–332CrossRefPubMed Edwards RR, Bingham CO 3rd, Bathon J, Haythornthwaite JA (2006) Catastrophizing and pain in arthritis, fibromyalgia, and other rheumatic diseases. Arthritis Rheum 55(2):325–332CrossRefPubMed
12.
Zurück zum Zitat Edwards RR, Haythornthwaite JA, Smith MT, Klick B, Katz JN (2009) Catastrophizing and depressive symptoms as prospective predictors of outcomes following total knee replacement. Pain Res Manag 14(4):307–311CrossRefPubMedPubMedCentral Edwards RR, Haythornthwaite JA, Smith MT, Klick B, Katz JN (2009) Catastrophizing and depressive symptoms as prospective predictors of outcomes following total knee replacement. Pain Res Manag 14(4):307–311CrossRefPubMedPubMedCentral
13.
Zurück zum Zitat Faller H, Kirschner S, König A (2003) Psychological distress predicts functional outcomes at three and twelve months after total knee arthroplasty. Gen Hosp Psychiatry 25(5):372–373CrossRefPubMed Faller H, Kirschner S, König A (2003) Psychological distress predicts functional outcomes at three and twelve months after total knee arthroplasty. Gen Hosp Psychiatry 25(5):372–373CrossRefPubMed
14.
Zurück zum Zitat Filardo G, Roffi A, Merli G, Marcacci T, Ceroni FB, Raboni D, Bortolotti B, De Pasqual L, Marcacci M (2015) Patient kinesiophobia affects both recovery time and final outcome after total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc. doi:10.1007/s00167-015-3898-8 Filardo G, Roffi A, Merli G, Marcacci T, Ceroni FB, Raboni D, Bortolotti B, De Pasqual L, Marcacci M (2015) Patient kinesiophobia affects both recovery time and final outcome after total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc. doi:10.​1007/​s00167-015-3898-8
15.
Zurück zum Zitat Fisher DA, Dierckman B, Watts MR, Davis K (2007) Looks good but feels bad: factors that contribute to poor results after total knee arthroplasty. J Arthroplasty 22(6 Suppl 2):39–42CrossRefPubMed Fisher DA, Dierckman B, Watts MR, Davis K (2007) Looks good but feels bad: factors that contribute to poor results after total knee arthroplasty. J Arthroplasty 22(6 Suppl 2):39–42CrossRefPubMed
16.
Zurück zum Zitat Flanigan DC, Everhart JS, Glassman AH (2015) Psychological factors affecting rehabilitation and outcomes following elective orthopaedic surgery. J Am Acad Orthop Surg 23(9):563–570CrossRefPubMed Flanigan DC, Everhart JS, Glassman AH (2015) Psychological factors affecting rehabilitation and outcomes following elective orthopaedic surgery. J Am Acad Orthop Surg 23(9):563–570CrossRefPubMed
17.
Zurück zum Zitat Fortin PR, Clarke AE, Joseph L, Liang MH, Tanzer M, Ferland D, Phillips C, Partridge AJ, Bélisle P, Fossel AH, Mahomed N, Sledge CB, Katz JN (1999) Outcomes of total hip and knee replacement: preoperative functional status predicts outcomes at six months after surgery. Arthritis Rheum 42(8):1722–1728CrossRefPubMed Fortin PR, Clarke AE, Joseph L, Liang MH, Tanzer M, Ferland D, Phillips C, Partridge AJ, Bélisle P, Fossel AH, Mahomed N, Sledge CB, Katz JN (1999) Outcomes of total hip and knee replacement: preoperative functional status predicts outcomes at six months after surgery. Arthritis Rheum 42(8):1722–1728CrossRefPubMed
18.
Zurück zum Zitat Goodin BR, McGuire L, Allshouse M, Stapleton L, Haythornthwaite JA, Burns N, Mayes LA, Edwards RR (2009) Associations between catastrophizing and endogenous pain-inhibitory processes: sex differences. J Pain 10(2):180–190CrossRefPubMed Goodin BR, McGuire L, Allshouse M, Stapleton L, Haythornthwaite JA, Burns N, Mayes LA, Edwards RR (2009) Associations between catastrophizing and endogenous pain-inhibitory processes: sex differences. J Pain 10(2):180–190CrossRefPubMed
19.
Zurück zum Zitat Gracely RH, Geisser ME, Giesecke T, Grant MA, Petzke F, Williams DA, Clauw DJ (2004) Pain catastrophizing and neural responses to pain among persons with fibromyalgia. Brain 127(Pt 4):835–843CrossRefPubMed Gracely RH, Geisser ME, Giesecke T, Grant MA, Petzke F, Williams DA, Clauw DJ (2004) Pain catastrophizing and neural responses to pain among persons with fibromyalgia. Brain 127(Pt 4):835–843CrossRefPubMed
20.
Zurück zum Zitat Granot M (2009) Can we predict persistent postoperative pain by testing preoperative experimental pain? Curr Opin Anaesthesiol 22(3):425–430CrossRefPubMed Granot M (2009) Can we predict persistent postoperative pain by testing preoperative experimental pain? Curr Opin Anaesthesiol 22(3):425–430CrossRefPubMed
21.
Zurück zum Zitat Gros DF, Antony MM, Simms LJ, McCabe RE (2007) Psychometric properties of the State-Trait Inventory for Cognitive and Somatic Anxiety (STICSA): comparison to the State-Trait Anxiety Inventory (STAI). Psychol Assess 19:369–381CrossRefPubMed Gros DF, Antony MM, Simms LJ, McCabe RE (2007) Psychometric properties of the State-Trait Inventory for Cognitive and Somatic Anxiety (STICSA): comparison to the State-Trait Anxiety Inventory (STAI). Psychol Assess 19:369–381CrossRefPubMed
22.
Zurück zum Zitat Hawker G, Wright J, Coyte P, Paul J, Dittus R, Croxford R, Katz B, Bombardier C, Heck D, Freund D (1998) Health-related quality of life after knee replacement. J Bone Joint Surg Am 80(2):163–173CrossRefPubMed Hawker G, Wright J, Coyte P, Paul J, Dittus R, Croxford R, Katz B, Bombardier C, Heck D, Freund D (1998) Health-related quality of life after knee replacement. J Bone Joint Surg Am 80(2):163–173CrossRefPubMed
23.
Zurück zum Zitat Hirakawa Y, Hara M, Fujiwara A, Hanada H, Morioka S (2014) The relationship among psychological factors, neglect-like symptoms and postoperative pain after total knee arthroplasty. Pain Res Manag 19(5):251–256CrossRefPubMedPubMedCentral Hirakawa Y, Hara M, Fujiwara A, Hanada H, Morioka S (2014) The relationship among psychological factors, neglect-like symptoms and postoperative pain after total knee arthroplasty. Pain Res Manag 19(5):251–256CrossRefPubMedPubMedCentral
24.
Zurück zum Zitat Hirschmann MT, Testa E, Amsler F, Friederich NF (2013) The unhappy total knee arthroplasty (TKA) patient: higher WOMAC and lower KSS in depressed patients prior and after TKA. Knee Surg Sports Traumatol Arthrosc 21(10):2405–2411CrossRefPubMed Hirschmann MT, Testa E, Amsler F, Friederich NF (2013) The unhappy total knee arthroplasty (TKA) patient: higher WOMAC and lower KSS in depressed patients prior and after TKA. Knee Surg Sports Traumatol Arthrosc 21(10):2405–2411CrossRefPubMed
25.
Zurück zum Zitat Kocic M, Stankovic A, Lazovic M, Dimitrijevic L, Stankovic I, Spalevic M, Stojiljkovic P, Milenkovic M, Stojanovic Z, Nikolic D (2015) Influence of fear of movement on total knee arthroplasty outcome. Ann Ital Chir 86:148–155PubMed Kocic M, Stankovic A, Lazovic M, Dimitrijevic L, Stankovic I, Spalevic M, Stojiljkovic P, Milenkovic M, Stojanovic Z, Nikolic D (2015) Influence of fear of movement on total knee arthroplasty outcome. Ann Ital Chir 86:148–155PubMed
26.
Zurück zum Zitat Leeuw M, Goossens ME, Linton SJ, Crombez G, Boersma K, Vlaeyen JW (2007) The fear-avoidance model of musculoskeletal pain: current state of scientific evidence. J Behav Med 30(1):77–94CrossRefPubMed Leeuw M, Goossens ME, Linton SJ, Crombez G, Boersma K, Vlaeyen JW (2007) The fear-avoidance model of musculoskeletal pain: current state of scientific evidence. J Behav Med 30(1):77–94CrossRefPubMed
27.
Zurück zum Zitat Lewis GN, Rice DA, McNair PJ, Kluger M (2015) Predictors of persistent pain after total knee arthroplasty: a systematic review and meta-analysis. Br J Anaesth 114(4):551–561CrossRefPubMed Lewis GN, Rice DA, McNair PJ, Kluger M (2015) Predictors of persistent pain after total knee arthroplasty: a systematic review and meta-analysis. Br J Anaesth 114(4):551–561CrossRefPubMed
28.
Zurück zum Zitat Lykke J, Hesse M, Austin SF, Oestrich I (2008) Validity of the BPRS, the BDI and the BAI in dual diagnosis patients. Addict Behav 33(2):292–300CrossRefPubMed Lykke J, Hesse M, Austin SF, Oestrich I (2008) Validity of the BPRS, the BDI and the BAI in dual diagnosis patients. Addict Behav 33(2):292–300CrossRefPubMed
29.
Zurück zum Zitat Monticone M, Ferrante S, Rocca B, Salvaderi S, Fiorentini R, Restelli M, Foti C (2013) Home-based functional exercises aimed at managing kinesiophobia contribute to improving disability and quality of life of patients undergoing total knee arthroplasty: a randomized controlled trial. Arch Phys Med Rehabil 94(2):231–239CrossRefPubMed Monticone M, Ferrante S, Rocca B, Salvaderi S, Fiorentini R, Restelli M, Foti C (2013) Home-based functional exercises aimed at managing kinesiophobia contribute to improving disability and quality of life of patients undergoing total knee arthroplasty: a randomized controlled trial. Arch Phys Med Rehabil 94(2):231–239CrossRefPubMed
30.
Zurück zum Zitat Monticone M, Giorgi I, Baiardi P, Barbieri M, Rocca B, Bonezzi C (2010) Development of the Italian version of the Tampa Scale of Kinesiophobia (TSK-I): cross-cultural adaptation, factor analysis, reliability, and validity. Spine 35(12):1241–1246CrossRefPubMed Monticone M, Giorgi I, Baiardi P, Barbieri M, Rocca B, Bonezzi C (2010) Development of the Italian version of the Tampa Scale of Kinesiophobia (TSK-I): cross-cultural adaptation, factor analysis, reliability, and validity. Spine 35(12):1241–1246CrossRefPubMed
31.
Zurück zum Zitat Sullivan M, Tanzer M, Stanish W, Fallaha M, Keefe FJ, Simmonds M, Dunbar M (2009) Psychological determinants of problematic outcomes following total knee arthroplasty. Pain 143(1–2):123–129CrossRefPubMed Sullivan M, Tanzer M, Stanish W, Fallaha M, Keefe FJ, Simmonds M, Dunbar M (2009) Psychological determinants of problematic outcomes following total knee arthroplasty. Pain 143(1–2):123–129CrossRefPubMed
32.
Zurück zum Zitat Turner JA, Mancl L, Aaron LA (2006) Short- and long-term efficacy of brief cognitive-behavioral therapy for patients with chronic temporomandibular disorder pain: a randomized, controlled trial. Pain 121(3):181–194CrossRefPubMed Turner JA, Mancl L, Aaron LA (2006) Short- and long-term efficacy of brief cognitive-behavioral therapy for patients with chronic temporomandibular disorder pain: a randomized, controlled trial. Pain 121(3):181–194CrossRefPubMed
33.
Zurück zum Zitat Unver B, Ertekin Ö, Karatosun V (2014) Pain, fear of falling and stair climbing ability in patients with knee osteoarthritis before and after knee replacement: 6 month follow-up study. J Back Musculoskelet Rehabil 27(1):77–84CrossRefPubMed Unver B, Ertekin Ö, Karatosun V (2014) Pain, fear of falling and stair climbing ability in patients with knee osteoarthritis before and after knee replacement: 6 month follow-up study. J Back Musculoskelet Rehabil 27(1):77–84CrossRefPubMed
34.
Zurück zum Zitat Vlaeyen JW, Linton SJ (2000) Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art. Pain 85(3):317–332CrossRefPubMed Vlaeyen JW, Linton SJ (2000) Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art. Pain 85(3):317–332CrossRefPubMed
35.
Zurück zum Zitat Wade JB, Riddle DL, Thacker LR (2012) Is pain catastrophizing a stable trait or dynamic state in patients scheduled for knee arthroplasty? Clin J Pain 28(2):122–128CrossRefPubMed Wade JB, Riddle DL, Thacker LR (2012) Is pain catastrophizing a stable trait or dynamic state in patients scheduled for knee arthroplasty? Clin J Pain 28(2):122–128CrossRefPubMed
36.
Zurück zum Zitat Ware J Jr, Kosinski M, Keller SD (1996) A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care 34(3):220–233CrossRefPubMed Ware J Jr, Kosinski M, Keller SD (1996) A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care 34(3):220–233CrossRefPubMed
37.
Zurück zum Zitat Witvrouw E, Pattyn E, Almqvist KF, Crombez G, Accoe C, Cambier D, Verdonk R (2009) Catastrophic thinking about pain as a predictor of length of hospital stay after total knee arthroplasty: a prospective study. Knee Surg Sports Traumatol Arthrosc 17(10):1189–1194CrossRefPubMed Witvrouw E, Pattyn E, Almqvist KF, Crombez G, Accoe C, Cambier D, Verdonk R (2009) Catastrophic thinking about pain as a predictor of length of hospital stay after total knee arthroplasty: a prospective study. Knee Surg Sports Traumatol Arthrosc 17(10):1189–1194CrossRefPubMed
38.
Zurück zum Zitat Wylde V, Dieppe P, Hewlett S, Learmonth ID (2007) Total knee replacement: is it really an effective procedure for all? Knee 14(6):417–423CrossRefPubMed Wylde V, Dieppe P, Hewlett S, Learmonth ID (2007) Total knee replacement: is it really an effective procedure for all? Knee 14(6):417–423CrossRefPubMed
Metadaten
Titel
Kinesiophobia and depression affect total knee arthroplasty outcome in a multivariate analysis of psychological and physical factors on 200 patients
verfasst von
G. Filardo
G. Merli
A. Roffi
T. Marcacci
F. Berti Ceroni
D. Raboni
B. Bortolotti
E. Kon
M. Marcacci
Publikationsdatum
21.06.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Knee Surgery, Sports Traumatology, Arthroscopy / Ausgabe 11/2017
Print ISSN: 0942-2056
Elektronische ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-016-4201-3

Weitere Artikel der Ausgabe 11/2017

Knee Surgery, Sports Traumatology, Arthroscopy 11/2017 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Arthroskopie kann Knieprothese nicht hinauszögern

25.04.2024 Gonarthrose Nachrichten

Ein arthroskopischer Eingriff bei Kniearthrose macht im Hinblick darauf, ob und wann ein Gelenkersatz fällig wird, offenbar keinen Unterschied.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Ärztliche Empathie hilft gegen Rückenschmerzen

23.04.2024 Leitsymptom Rückenschmerzen Nachrichten

Personen mit chronischen Rückenschmerzen, die von einfühlsamen Ärzten und Ärztinnen betreut werden, berichten über weniger Beschwerden und eine bessere Lebensqualität.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.