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2022 | OriginalPaper | Buchkapitel

25. Leberresektion

verfasst von : Ingo Klein

Erschienen in: Nicht-alkoholische Fettlebererkrankung

Verlag: Springer Berlin Heidelberg

Zusammenfassung

Bei Patienten mit nicht-alkoholischer Fettlebererkrankung (NAFLD) und insbesondere Steatohepatitis (NASH) besteht eine erhöhte perioperative Morbidität und Mortalität. Daher kommt der Evaluation des nach der Resektion verbleibenden Lebergewebes quantitativ und qualitativ eine entscheidende Bedeutung zu. Präoperative Leberfunktionstests besitzen bei milder und mäßiger Steatose und Leberfibrose eine deutlich höhere Trennschärfe und haben daher in den letzten Jahren an Bedeutung gewonnen. Soweit präoperative Verbesserungen durch Re-Konditionierung, Hypertrophieinduktion, Reduktion von Entzündung oder Steatosegrades bzw. der Behandlung von Begleiterkrankungen möglich ist, sollten diese ggf. auch unter Verwendung von Bridging-Maßnahmen zur Anwendung kommen. Bei der chirurgischen Resektion sind, insbesondere bei eingeschränkter Leberfunktion, Parenchym-sparende Resektionsverfahren zu bevorzugen. Die Vorteile minimalinvasiver Techniken hinsichtlich des Zugangstraumas müssen mit dem eventuell erhöhten Parenchymverlust abgewogen werden.
Literatur
Zurück zum Zitat Ju M, Yopp AC (2019) The utility of anatomical liver resection in hepatocellular carcinoma: associated with improved outcomes or lack of supportive evidence? Cancers (Basel) 11(10):1441 CrossRef Ju M, Yopp AC (2019) The utility of anatomical liver resection in hepatocellular carcinoma: associated with improved outcomes or lack of supportive evidence? Cancers (Basel) 11(10):1441 CrossRef
Zurück zum Zitat Abdelsalam ME, Murthy R, Avritscher R, Mahvash A, Wallace MJ, Kaseb AO et al (2016) Minimally invasive image-guided therapies for hepatocellular carcinoma. J Hepatocell Carcinoma 3:55–61PubMedPubMedCentralCrossRef Abdelsalam ME, Murthy R, Avritscher R, Mahvash A, Wallace MJ, Kaseb AO et al (2016) Minimally invasive image-guided therapies for hepatocellular carcinoma. J Hepatocell Carcinoma 3:55–61PubMedPubMedCentralCrossRef
Zurück zum Zitat Alizai PH, Lurje I, Kroh A, Schmitz S, Luedde T, Andruszkow J et al (2019) Noninvasive evaluation of liver function in morbidly obese patients. Gastroenterol Res Pract 2019:4307462PubMedPubMedCentralCrossRef Alizai PH, Lurje I, Kroh A, Schmitz S, Luedde T, Andruszkow J et al (2019) Noninvasive evaluation of liver function in morbidly obese patients. Gastroenterol Res Pract 2019:4307462PubMedPubMedCentralCrossRef
Zurück zum Zitat Behrns KE, Tsiotos GG, DeSouza NF, Krishna MK, Ludwig J, Nagorney DM (1998) Hepatic steatosis as a potential risk factor for major hepatic resection. J Gastrointest Surg 2(3):292–298PubMedCrossRef Behrns KE, Tsiotos GG, DeSouza NF, Krishna MK, Ludwig J, Nagorney DM (1998) Hepatic steatosis as a potential risk factor for major hepatic resection. J Gastrointest Surg 2(3):292–298PubMedCrossRef
Zurück zum Zitat Bhayani NH, Hyder O, Frederick W, Schulick RD, Wolgang CL, Hirose K et al (2012) Effect of metabolic syndrome on perioperative outcomes after liver surgery: a National Surgical Quality Improvement Program (NSQIP) analysis. Surgery 152(2):218–226PubMedCrossRef Bhayani NH, Hyder O, Frederick W, Schulick RD, Wolgang CL, Hirose K et al (2012) Effect of metabolic syndrome on perioperative outcomes after liver surgery: a National Surgical Quality Improvement Program (NSQIP) analysis. Surgery 152(2):218–226PubMedCrossRef
Zurück zum Zitat Browning JD, Baker JA, Rogers T, Davis J, Satapati S, Burgess SC (2011) Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction. Am J Clin Nutr 93(5):1048–1052PubMedPubMedCentralCrossRef Browning JD, Baker JA, Rogers T, Davis J, Satapati S, Burgess SC (2011) Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction. Am J Clin Nutr 93(5):1048–1052PubMedPubMedCentralCrossRef
Zurück zum Zitat Bruix J, Sherman M (2011) American association for the study of Liver D. Management of hepatocellular carcinoma: an update. Hepatology 53(3):1020–1022PubMedCrossRef Bruix J, Sherman M (2011) American association for the study of Liver D. Management of hepatocellular carcinoma: an update. Hepatology 53(3):1020–1022PubMedCrossRef
Zurück zum Zitat Bruix J, Reig M, Sherman M (2016) Evidence-based diagnosis, staging, and treatment of patients with hepatocellular carcinoma. Gastroenterology 150(4):835–853PubMedCrossRef Bruix J, Reig M, Sherman M (2016) Evidence-based diagnosis, staging, and treatment of patients with hepatocellular carcinoma. Gastroenterology 150(4):835–853PubMedCrossRef
Zurück zum Zitat Cauchy F, Zalinski S, Dokmak S, Fuks D, Farges O, Castera L et al (2013) Surgical treatment of hepatocellular carcinoma associated with the metabolic syndrome. Br J Surg 100(1):113–121PubMedCrossRef Cauchy F, Zalinski S, Dokmak S, Fuks D, Farges O, Castera L et al (2013) Surgical treatment of hepatocellular carcinoma associated with the metabolic syndrome. Br J Surg 100(1):113–121PubMedCrossRef
Zurück zum Zitat De Gasperi A, Mazza E, Prosperi M (2016) Indocyanine green kinetics to assess liver function: ready for a clinical dynamic assessment in major liver surgery? World J Hepatol 8(7):355–367PubMedPubMedCentralCrossRef De Gasperi A, Mazza E, Prosperi M (2016) Indocyanine green kinetics to assess liver function: ready for a clinical dynamic assessment in major liver surgery? World J Hepatol 8(7):355–367PubMedPubMedCentralCrossRef
Zurück zum Zitat de Meijer VE, Kalish BT, Puder M, Ijzermans JN (2010) Systematic review and meta-analysis of steatosis as a risk factor in major hepatic resection. Br J Surg 97(9):1331–1339PubMedCrossRef de Meijer VE, Kalish BT, Puder M, Ijzermans JN (2010) Systematic review and meta-analysis of steatosis as a risk factor in major hepatic resection. Br J Surg 97(9):1331–1339PubMedCrossRef
Zurück zum Zitat Deng G, Li H, Jia GQ, Fang D, Tang YY, Xie J et al (2019) Parenchymal-sparing versus extended hepatectomy for colorectal liver metastases: a systematic review and meta-analysis. Cancer Med 8(14):6165–6175PubMedPubMedCentralCrossRef Deng G, Li H, Jia GQ, Fang D, Tang YY, Xie J et al (2019) Parenchymal-sparing versus extended hepatectomy for colorectal liver metastases: a systematic review and meta-analysis. Cancer Med 8(14):6165–6175PubMedPubMedCentralCrossRef
Zurück zum Zitat Doherty DT, Coe PO, Rimmer L, Lapsia S, Krige A, Subar DA (2019) Hepatic steatosis in patients undergoing resection of colorectal liver metastases: A target for prehabilitation? A Narrat Rev Surg Oncol 30:147–158CrossRef Doherty DT, Coe PO, Rimmer L, Lapsia S, Krige A, Subar DA (2019) Hepatic steatosis in patients undergoing resection of colorectal liver metastases: A target for prehabilitation? A Narrat Rev Surg Oncol 30:147–158CrossRef
Zurück zum Zitat Edholm D, Kullberg J, Haenni A, Karlsson FA, Ahlstrom A, Hedberg J et al (2011) Preoperative 4-week low-calorie diet reduces liver volume and intrahepatic fat, and facilitates laparoscopic gastric bypass in morbidly obese. Obes Surg 21(3):345–350PubMedCrossRef Edholm D, Kullberg J, Haenni A, Karlsson FA, Ahlstrom A, Hedberg J et al (2011) Preoperative 4-week low-calorie diet reduces liver volume and intrahepatic fat, and facilitates laparoscopic gastric bypass in morbidly obese. Obes Surg 21(3):345–350PubMedCrossRef
Zurück zum Zitat Folprecht G, Gruenberger T, Bechstein W, Raab HR, Weitz J, Lordick F et al (2014) Survival of patients with initially unresectable colorectal liver metastases treated with FOLFOX/cetuximab or FOLFIRI/cetuximab in a multidisciplinary concept (CELIM study). Ann Oncol. 25(5):1018–1025PubMedCrossRef Folprecht G, Gruenberger T, Bechstein W, Raab HR, Weitz J, Lordick F et al (2014) Survival of patients with initially unresectable colorectal liver metastases treated with FOLFOX/cetuximab or FOLFIRI/cetuximab in a multidisciplinary concept (CELIM study). Ann Oncol. 25(5):1018–1025PubMedCrossRef
Zurück zum Zitat Hallet J, Jayaraman S, Martel G, Ouellet JB, Lin Y, McCluskey S et al (2019) Patient blood management for liver resection: consensus statements using Delphi methodology. HPB (Oxford) 21(4):393–404CrossRef Hallet J, Jayaraman S, Martel G, Ouellet JB, Lin Y, McCluskey S et al (2019) Patient blood management for liver resection: consensus statements using Delphi methodology. HPB (Oxford) 21(4):393–404CrossRef
Zurück zum Zitat Hobeika C, Cauchy F, Pote N, Rautou PE, Durand F, Farges O et al (2019a) Short- and long-term outcomes of liver resection for intrahepatic cholangiocarcinoma associated with the metabolic syndrome. World J Surg 43(8):2048–2060PubMedCrossRef Hobeika C, Cauchy F, Pote N, Rautou PE, Durand F, Farges O et al (2019a) Short- and long-term outcomes of liver resection for intrahepatic cholangiocarcinoma associated with the metabolic syndrome. World J Surg 43(8):2048–2060PubMedCrossRef
Zurück zum Zitat Hobeika C, Ronot M, Beaufrere A, Paradis V, Soubrane O, Cauchy F (2019b) Metabolic syndrome and hepatic surgery. J Visc Surg 157(3):231–238 PubMedCrossRef Hobeika C, Ronot M, Beaufrere A, Paradis V, Soubrane O, Cauchy F (2019b) Metabolic syndrome and hepatic surgery. J Visc Surg 157(3):231–238 PubMedCrossRef
Zurück zum Zitat Hollingsworth KG, Abubacker MZ, Joubert I, Allison ME, Lomas DJ (2006) Low-carbohydrate diet induced reduction of hepatic lipid content observed with a rapid non-invasive MRI technique. Br J Radiol 79(945):712–715PubMedCrossRef Hollingsworth KG, Abubacker MZ, Joubert I, Allison ME, Lomas DJ (2006) Low-carbohydrate diet induced reduction of hepatic lipid content observed with a rapid non-invasive MRI technique. Br J Radiol 79(945):712–715PubMedCrossRef
Zurück zum Zitat Huang HC, Bian J, Bai Y, Lu X, Xu YY, Sang XT et al (2019) Complete or partial split in associating liver partition and portal vein ligation for staged hepatectomy: a systematic review and meta-analysis. World J Gastroenterol 25(39):6016–6024PubMedPubMedCentralCrossRef Huang HC, Bian J, Bai Y, Lu X, Xu YY, Sang XT et al (2019) Complete or partial split in associating liver partition and portal vein ligation for staged hepatectomy: a systematic review and meta-analysis. World J Gastroenterol 25(39):6016–6024PubMedPubMedCentralCrossRef
Zurück zum Zitat Jara M, Bednarsch J, Malinowski M, Pratschke J, Stockmann M (2016) Effects of oxaliplatin-based chemotherapy on liver function–an analysis of impact and functional recovery using the LiMAx test. Langenbecks Arch Surg 401(1):33–41PubMedCrossRef Jara M, Bednarsch J, Malinowski M, Pratschke J, Stockmann M (2016) Effects of oxaliplatin-based chemotherapy on liver function–an analysis of impact and functional recovery using the LiMAx test. Langenbecks Arch Surg 401(1):33–41PubMedCrossRef
Zurück zum Zitat Kanas GP, Taylor A, Primrose JN, Langeberg WJ, Kelsh MA, Mowat FS et al (2012) Survival after liver resection in metastatic colorectal cancer: review and meta-analysis of prognostic factors. Clin Epidemiol 4:283–301PubMedPubMedCentral Kanas GP, Taylor A, Primrose JN, Langeberg WJ, Kelsh MA, Mowat FS et al (2012) Survival after liver resection in metastatic colorectal cancer: review and meta-analysis of prognostic factors. Clin Epidemiol 4:283–301PubMedPubMedCentral
Zurück zum Zitat Kooby DA, Fong Y, Suriawinata A, Gonen M, Allen PJ, Klimstra DS et al (2003) Impact of steatosis on perioperative outcome following hepatic resection. J Gastrointest Surg 7(8):1034–1044PubMedCrossRef Kooby DA, Fong Y, Suriawinata A, Gonen M, Allen PJ, Klimstra DS et al (2003) Impact of steatosis on perioperative outcome following hepatic resection. J Gastrointest Surg 7(8):1034–1044PubMedCrossRef
Zurück zum Zitat Kozloff M, Yood MU, Berlin J, Flynn PJ, Kabbinavar FF, Purdie DM et al (2009) Clinical outcomes associated with bevacizumab-containing treatment of metastatic colorectal cancer: the BRiTE observational cohort study. Oncologist 14(9):862–870PubMedCrossRef Kozloff M, Yood MU, Berlin J, Flynn PJ, Kabbinavar FF, Purdie DM et al (2009) Clinical outcomes associated with bevacizumab-containing treatment of metastatic colorectal cancer: the BRiTE observational cohort study. Oncologist 14(9):862–870PubMedCrossRef
Zurück zum Zitat Lock JF, Kotobi AN, Malinowski M, Schulz A, Jara M, Neuhaus P et al (2013) Predicting the prognosis in acute liver failure: results from a retrospective pilot study using the LiMAx test. Ann Hepatol 12(4):556–562PubMedCrossRef Lock JF, Kotobi AN, Malinowski M, Schulz A, Jara M, Neuhaus P et al (2013) Predicting the prognosis in acute liver failure: results from a retrospective pilot study using the LiMAx test. Ann Hepatol 12(4):556–562PubMedCrossRef
Zurück zum Zitat Lock JF, Westphal T, Rubin T, Malinowski M, Schulz A, Jara M et al (2017) LiMAx test improves diagnosis of chemotherapy-associated liver injury before resection of colorectal liver metastases. Ann Surg Oncol 24(9):2447–2455PubMedCrossRef Lock JF, Westphal T, Rubin T, Malinowski M, Schulz A, Jara M et al (2017) LiMAx test improves diagnosis of chemotherapy-associated liver injury before resection of colorectal liver metastases. Ann Surg Oncol 24(9):2447–2455PubMedCrossRef
Zurück zum Zitat Massani M, Capovilla G, Ruffolo C, Bonariol R, Maccatrozzo P, Tuci F et al (2017) Blood transfusions and steatohepatitis are independent risk factors for complications following liver resection for colorectal cancer liver metastases. Mol Clin Oncol 7(4):529–538PubMedPubMedCentralCrossRef Massani M, Capovilla G, Ruffolo C, Bonariol R, Maccatrozzo P, Tuci F et al (2017) Blood transfusions and steatohepatitis are independent risk factors for complications following liver resection for colorectal cancer liver metastases. Mol Clin Oncol 7(4):529–538PubMedPubMedCentralCrossRef
Zurück zum Zitat Nordlinger B, Sorbye H, Glimelius B, Poston GJ, Schlag PM, Rougier P et al (2013) Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial. Lancet Oncol 14(12):1208–1215PubMedCrossRef Nordlinger B, Sorbye H, Glimelius B, Poston GJ, Schlag PM, Rougier P et al (2013) Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial. Lancet Oncol 14(12):1208–1215PubMedCrossRef
Zurück zum Zitat Parkin E, O’Reilly DA, Adam R, Kaiser GM, Laurent C, Elias D et al (2013) The effect of hepatic steatosis on survival following resection of colorectal liver metastases in patients without preoperative chemotherapy. HPB (Oxford) 15(6):463–472CrossRef Parkin E, O’Reilly DA, Adam R, Kaiser GM, Laurent C, Elias D et al (2013) The effect of hepatic steatosis on survival following resection of colorectal liver metastases in patients without preoperative chemotherapy. HPB (Oxford) 15(6):463–472CrossRef
Zurück zum Zitat Parkin E, O’Reilly DA, Adam R, Kaiser GM, Laurent C, Elias D et al (2014) Equivalent survival in patients with and without steatosis undergoing resection for colorectal liver metastases following pre-operative chemotherapy. Eur J Surg Oncol 40(11):1436–1444PubMedCrossRef Parkin E, O’Reilly DA, Adam R, Kaiser GM, Laurent C, Elias D et al (2014) Equivalent survival in patients with and without steatosis undergoing resection for colorectal liver metastases following pre-operative chemotherapy. Eur J Surg Oncol 40(11):1436–1444PubMedCrossRef
Zurück zum Zitat Pilgrim CH, Satgunaseelan L, Pham A, Murray W, Link E, Smith M et al (2012) Correlations between histopathological diagnosis of chemotherapy-induced hepatic injury, clinical features, and perioperative morbidity. HPB (Oxford) 14(5):333–340CrossRef Pilgrim CH, Satgunaseelan L, Pham A, Murray W, Link E, Smith M et al (2012) Correlations between histopathological diagnosis of chemotherapy-induced hepatic injury, clinical features, and perioperative morbidity. HPB (Oxford) 14(5):333–340CrossRef
Zurück zum Zitat Piwowarska J, Kuczynska J, Pachecka J (2004) Liquid chromatographic method for the determination of lidocaine and monoethylglycine xylidide in human serum containing various concentrations of bilirubin for the assessment of liver function. J Chromatogr B Analyt Technol Biomed Life Sci 805(1):1–5PubMedCrossRef Piwowarska J, Kuczynska J, Pachecka J (2004) Liquid chromatographic method for the determination of lidocaine and monoethylglycine xylidide in human serum containing various concentrations of bilirubin for the assessment of liver function. J Chromatogr B Analyt Technol Biomed Life Sci 805(1):1–5PubMedCrossRef
Zurück zum Zitat Pruvot FR, Truant S (2016) Major hepatic resection: from volumetry to liver scintigraphy. HPB (Oxford) 18(9):707–708CrossRef Pruvot FR, Truant S (2016) Major hepatic resection: from volumetry to liver scintigraphy. HPB (Oxford) 18(9):707–708CrossRef
Zurück zum Zitat Raptis DA, Fischer MA, Graf R, Nanz D, Weber A, Moritz W et al (2012) MRI: the new reference standard in quantifying hepatic steatosis? Gut 61(1):117–127PubMedCrossRef Raptis DA, Fischer MA, Graf R, Nanz D, Weber A, Moritz W et al (2012) MRI: the new reference standard in quantifying hepatic steatosis? Gut 61(1):117–127PubMedCrossRef
Zurück zum Zitat Reeves JG, Suriawinata AA, Ng DP, Holubar SD, Mills JB, Barth RJ Jr (2013) Short-term preoperative diet modification reduces steatosis and blood loss in patients undergoing liver resection. Surgery 154(5):1031–1037PubMedCrossRef Reeves JG, Suriawinata AA, Ng DP, Holubar SD, Mills JB, Barth RJ Jr (2013) Short-term preoperative diet modification reduces steatosis and blood loss in patients undergoing liver resection. Surgery 154(5):1031–1037PubMedCrossRef
Zurück zum Zitat Ryan MC, Itsiopoulos C, Thodis T, Ward G, Trost N, Hofferberth S et al (2013) The Mediterranean diet improves hepatic steatosis and insulin sensitivity in individuals with non-alcoholic fatty liver disease. J Hepatol 59(1):138–143PubMedCrossRef Ryan MC, Itsiopoulos C, Thodis T, Ward G, Trost N, Hofferberth S et al (2013) The Mediterranean diet improves hepatic steatosis and insulin sensitivity in individuals with non-alcoholic fatty liver disease. J Hepatol 59(1):138–143PubMedCrossRef
Zurück zum Zitat Schwenzer NF, Springer F, Schraml C, Stefan N, Machann J, Schick F (2009) Non-invasive assessment and quantification of liver steatosis by ultrasound, computed tomography and magnetic resonance. J Hepatol 51(3):433–445PubMedCrossRef Schwenzer NF, Springer F, Schraml C, Stefan N, Machann J, Schick F (2009) Non-invasive assessment and quantification of liver steatosis by ultrasound, computed tomography and magnetic resonance. J Hepatol 51(3):433–445PubMedCrossRef
Zurück zum Zitat Stockmann M, Lock JF, Malinowski M, Seehofer D, Puhl G, Pratschke J et al (2010b) How to define initial poor graft function after liver transplantation? - a new functional definition by the LiMAx test. Transpl Int 23(10):1023–1032PubMedCrossRef Stockmann M, Lock JF, Malinowski M, Seehofer D, Puhl G, Pratschke J et al (2010b) How to define initial poor graft function after liver transplantation? - a new functional definition by the LiMAx test. Transpl Int 23(10):1023–1032PubMedCrossRef
Zurück zum Zitat Stockmann M, Lock JF, Malinowski M, Niehues SM, Seehofer D, Neuhaus P (2010a) The LiMAx test: a new liver function test for predicting postoperative outcome in liver surgery. HPB (Oxford) 12(2):139–146CrossRef Stockmann M, Lock JF, Malinowski M, Niehues SM, Seehofer D, Neuhaus P (2010a) The LiMAx test: a new liver function test for predicting postoperative outcome in liver surgery. HPB (Oxford) 12(2):139–146CrossRef
Zurück zum Zitat Stockmann M, Vondran FWR, Fahrner R, Tautenhahn HM, Mittler J, Bektas H et al (2018) Randomized clinical trial comparing liver resection with and without perioperative assessment of liver function. BJS Open 2(5):301–309PubMedPubMedCentralCrossRef Stockmann M, Vondran FWR, Fahrner R, Tautenhahn HM, Mittler J, Bektas H et al (2018) Randomized clinical trial comparing liver resection with and without perioperative assessment of liver function. BJS Open 2(5):301–309PubMedPubMedCentralCrossRef
Zurück zum Zitat Sultana A, Brooke M, Ullah S, Figueras J, Rees M, Vauthey JN et al (2018) Prospective evaluation of the International Study Group for Liver Surgery definition of post hepatectomy liver failure after liver resection: an international multicentre study. HPB (Oxford) 20(5):462–469CrossRef Sultana A, Brooke M, Ullah S, Figueras J, Rees M, Vauthey JN et al (2018) Prospective evaluation of the International Study Group for Liver Surgery definition of post hepatectomy liver failure after liver resection: an international multicentre study. HPB (Oxford) 20(5):462–469CrossRef
Zurück zum Zitat Tan Y, Zhang W, Jiang L, Yang J, Yan L (2017) Efficacy and safety of anatomic resection versus nonanatomic resection in patients with hepatocellular carcinoma: a systemic review and meta-analysis. PLoS ONE 12(10):e0186930PubMedPubMedCentralCrossRef Tan Y, Zhang W, Jiang L, Yang J, Yan L (2017) Efficacy and safety of anatomic resection versus nonanatomic resection in patients with hepatocellular carcinoma: a systemic review and meta-analysis. PLoS ONE 12(10):e0186930PubMedPubMedCentralCrossRef
Zurück zum Zitat Tran TB, Worhunsky DJ, Spain DA, Dua MM, Visser BC, Norton JA et al (2016) The significance of underlying cardiac comorbidity on major adverse cardiac events after major liver resection. HPB (Oxford) 18(9):742–747CrossRef Tran TB, Worhunsky DJ, Spain DA, Dua MM, Visser BC, Norton JA et al (2016) The significance of underlying cardiac comorbidity on major adverse cardiac events after major liver resection. HPB (Oxford) 18(9):742–747CrossRef
Zurück zum Zitat Vauthey JN, Pawlik TM, Ribero D, Wu TT, Zorzi D, Hoff PM et al (2006) Chemotherapy regimen predicts steatohepatitis and an increase in 90-day mortality after surgery for hepatic colorectal metastases. J Clin Oncol 24(13):2065–2072PubMedCrossRef Vauthey JN, Pawlik TM, Ribero D, Wu TT, Zorzi D, Hoff PM et al (2006) Chemotherapy regimen predicts steatohepatitis and an increase in 90-day mortality after surgery for hepatic colorectal metastases. J Clin Oncol 24(13):2065–2072PubMedCrossRef
Zurück zum Zitat Vogl TJ, Naguib NN, Nour NE, Rao P, Emami AH, Zangos S et al (2009) Review on transarterial chemoembolization in hepatocellular carcinoma: palliative, combined, neoadjuvant, bridging, and symptomatic indications. Eur J Radiol 72(3):505–516PubMedCrossRef Vogl TJ, Naguib NN, Nour NE, Rao P, Emami AH, Zangos S et al (2009) Review on transarterial chemoembolization in hepatocellular carcinoma: palliative, combined, neoadjuvant, bridging, and symptomatic indications. Eur J Radiol 72(3):505–516PubMedCrossRef
Zurück zum Zitat Wang ZY, Chen QL, Sun LL, He SP, Luo XF, Huang LS et al (2019) Laparoscopic versus open major liver resection for hepatocellular carcinoma: systematic review and meta-analysis of comparative cohort studies. BMC Cancer 19(1):1047PubMedPubMedCentralCrossRef Wang ZY, Chen QL, Sun LL, He SP, Luo XF, Huang LS et al (2019) Laparoscopic versus open major liver resection for hepatocellular carcinoma: systematic review and meta-analysis of comparative cohort studies. BMC Cancer 19(1):1047PubMedPubMedCentralCrossRef
Zurück zum Zitat Welsh FK, Tilney HS, Tekkis PP, John TG, Rees M (2007) Safe liver resection following chemotherapy for colorectal metastases is a matter of timing. Br J Cancer 96(7):1037–1042PubMedPubMedCentralCrossRef Welsh FK, Tilney HS, Tekkis PP, John TG, Rees M (2007) Safe liver resection following chemotherapy for colorectal metastases is a matter of timing. Br J Cancer 96(7):1037–1042PubMedPubMedCentralCrossRef
Zurück zum Zitat Ye JZ, Miao ZG, Wu FX, Zhao YN, Ye HH, Li LQ (2012) Recurrence after anatomic resection versus nonanatomic resection for hepatocellular carcinoma: a meta-analysis. Asian Pac J Cancer Prev 13(5):1771–1777PubMedCrossRef Ye JZ, Miao ZG, Wu FX, Zhao YN, Ye HH, Li LQ (2012) Recurrence after anatomic resection versus nonanatomic resection for hepatocellular carcinoma: a meta-analysis. Asian Pac J Cancer Prev 13(5):1771–1777PubMedCrossRef
Zurück zum Zitat Zhao J, van Mierlo KMC, Gomez J, Kim H, Pilgrim CHC, Pessaux P et al (2017) Systematic review of the influence of chemotherapy-associated liver injury on outcome after partial hepatectomy for colorectal liver metastases. Br J Surg 104(8):990–1002PubMedCrossRef Zhao J, van Mierlo KMC, Gomez J, Kim H, Pilgrim CHC, Pessaux P et al (2017) Systematic review of the influence of chemotherapy-associated liver injury on outcome after partial hepatectomy for colorectal liver metastases. Br J Surg 104(8):990–1002PubMedCrossRef
Zurück zum Zitat Zhou Y, Xu D, Wu L, Li B (2011) Meta-analysis of anatomic resection versus nonanatomic resection for hepatocellular carcinoma. Langenbecks Arch Surg 396(7):1109–1117PubMedCrossRef Zhou Y, Xu D, Wu L, Li B (2011) Meta-analysis of anatomic resection versus nonanatomic resection for hepatocellular carcinoma. Langenbecks Arch Surg 396(7):1109–1117PubMedCrossRef
Metadaten
Titel
Leberresektion
verfasst von
Ingo Klein
Copyright-Jahr
2022
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-662-62484-5_25

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