Skip to main content
Erschienen in: World Journal of Urology 7/2018

15.02.2018 | Original Article

Is mini-percutaneous nephrolithotomy a safe alternative to extracorporeal shockwave lithotripsy in pediatric age group in borderline stones? a randomized prospective study

verfasst von: Ahmed Farouk, Ahmed Tawfick, Mohamed Shoeb, Mahmoud A. Mahmoud, Diaa Eldin Mostafa, Mohamed Hasan, Hany M. Abdalla

Erschienen in: World Journal of Urology | Ausgabe 7/2018

Einloggen, um Zugang zu erhalten

Abstract

Purpose

The extracorporeal shockwave lithotripsy (ESWL) remains the most common first line of treatment for renal stones in the pediatric population. The purpose of this study is to evaluate and compare the outcomes of the ESWL and mini-percutaneous nephrolithotomy (mini-PCNL).

Patients and methods

A total of 108 patients younger than 12 years of age with 1–2 cm single renal stone (pelvic or calyceal) were randomized into two groups, each containing 54 patients. Patients in group A were subjected to mini-PCNL using 16.5 Fr percutaneous sheath while those in group B underwent ESWL using Dornier Compact Sigma.

Results

The stone-free rate (SFR) after first session was 88.9% (48 cases) and 55.6% (30 cases) for groups A and B, respectively. The difference is highly statistically significant P = 0.006. Two patients (3.7%) in group A needed 2nd session of PCNL, while 18 patients (33.3%)in group B needed a 2nd session, of theses 18 patients six patients needed a 3rd session of ESWL. After the third session of ESWL and second look PCNL the stone-free rates were 92.59% (50 cases) and 88.89% (48 cases) for groups A and B, respectively, (P = 0.639), which is statistically insignificant. The mean hospital stay and fluoroscopy exposure were significantly longer in the mini-PCNL group. The complication rate in groups A and group B were (22.2%) and (14.8%), respectively, which is statistically insignificant (P = 0.484).

Conclusions

According to Clavien grade of complications mini-PCNL is a safe procedure, and after three session of ESWL, mini-PCNL has a similar stone-free rate with a lower retreatment rate. However, the mini-PCNL has more radiation exposure, and requires a longer hospital stay.
Literatur
1.
Zurück zum Zitat Tasian GE, Copelovitch L (2014) Evaluation and medical management of kidney stones in children. J Urol 192:1329–1336CrossRefPubMed Tasian GE, Copelovitch L (2014) Evaluation and medical management of kidney stones in children. J Urol 192:1329–1336CrossRefPubMed
2.
Zurück zum Zitat Sabnis RB, Chhabra JS, Ganpule AP, Abrol S, Desai MR (2014) Current role of PCNL in pediatric urolithiasis. Curr Urol Rep 15:423CrossRefPubMed Sabnis RB, Chhabra JS, Ganpule AP, Abrol S, Desai MR (2014) Current role of PCNL in pediatric urolithiasis. Curr Urol Rep 15:423CrossRefPubMed
3.
Zurück zum Zitat Kolla SB, Wadhwa P, Aron M (2006) Current status of minimally invasive management of pediatric upper urinary tract calculi. J Indian Assoc Pediatr Surg 11(2):73CrossRef Kolla SB, Wadhwa P, Aron M (2006) Current status of minimally invasive management of pediatric upper urinary tract calculi. J Indian Assoc Pediatr Surg 11(2):73CrossRef
4.
Zurück zum Zitat Stamatiou KN, Heretis I, Takos D, Papadimitriou V, Sofras F (2010) Extracorporeal shock wave lithotripsy in the treatment of pediatric urolithiasis: a single institution experience, Department of Urology, School of Medicine, University of Crete, Crete, Greece. Int Braz J Urol 36:724–731CrossRefPubMed Stamatiou KN, Heretis I, Takos D, Papadimitriou V, Sofras F (2010) Extracorporeal shock wave lithotripsy in the treatment of pediatric urolithiasis: a single institution experience, Department of Urology, School of Medicine, University of Crete, Crete, Greece. Int Braz J Urol 36:724–731CrossRefPubMed
5.
Zurück zum Zitat Muslumanoglu AY, Tefekli A, Sarilar O et al (2003) (2003): extracorporeal shock wave lithotripsy as first line treatment alternative for urinary tract stones in children: A large scale retrospective analysis. J Urol 170:2405–2408CrossRefPubMed Muslumanoglu AY, Tefekli A, Sarilar O et al (2003) (2003): extracorporeal shock wave lithotripsy as first line treatment alternative for urinary tract stones in children: A large scale retrospective analysis. J Urol 170:2405–2408CrossRefPubMed
6.
Zurück zum Zitat Smaldone MC, Docimo SG, Ost MC (2010) Contemporary surgical management of pediatric urolithiasis. Urol Clin North Am 37:253–267CrossRefPubMed Smaldone MC, Docimo SG, Ost MC (2010) Contemporary surgical management of pediatric urolithiasis. Urol Clin North Am 37:253–267CrossRefPubMed
7.
Zurück zum Zitat Shu KL, Tai D, Chau L, Fung B (2006) Minimally invasive percutaneous nephrolithotomy (MPCNL) according to the Chinese method, interventional management of urological diseases. Recent Adv Endourol 8:41–63CrossRef Shu KL, Tai D, Chau L, Fung B (2006) Minimally invasive percutaneous nephrolithotomy (MPCNL) according to the Chinese method, interventional management of urological diseases. Recent Adv Endourol 8:41–63CrossRef
8.
Zurück zum Zitat Skolarikos A, de la Rosette J (2008) Prevention and treatment of complications following percutaneous nephrolithotomy. Curr Opin Urol 18:229–234CrossRefPubMed Skolarikos A, de la Rosette J (2008) Prevention and treatment of complications following percutaneous nephrolithotomy. Curr Opin Urol 18:229–234CrossRefPubMed
9.
Zurück zum Zitat Guven S, Istanbulluoglu O, Gul U, Ozturk A, Celik H, Aygun C, Ozdemir U, Ozturk B, Ozkardes H, Kilinc M (2011) Successful percutaneous nephrolithotomy in children: multicenter study on current status of its use, efficacy and complications using Clavien classification. J Urol 185:1419–1424CrossRefPubMed Guven S, Istanbulluoglu O, Gul U, Ozturk A, Celik H, Aygun C, Ozdemir U, Ozturk B, Ozkardes H, Kilinc M (2011) Successful percutaneous nephrolithotomy in children: multicenter study on current status of its use, efficacy and complications using Clavien classification. J Urol 185:1419–1424CrossRefPubMed
10.
Zurück zum Zitat Zeng GL, Jia J, Zhao Z, Wu W, Zhao Z, Zhong W (2012) Treatment of renal stones in infants: comparing extracorporeal shock wave lithotripsy and mini-percutaneous nephrolithotomy. Urol Res 40(5):599–603CrossRefPubMed Zeng GL, Jia J, Zhao Z, Wu W, Zhao Z, Zhong W (2012) Treatment of renal stones in infants: comparing extracorporeal shock wave lithotripsy and mini-percutaneous nephrolithotomy. Urol Res 40(5):599–603CrossRefPubMed
11.
Zurück zum Zitat Akin Y, Yucel S (2014) Long-term effects of pediatric extracorporeal shockwave lithotripsy on renal function. Res Rep Urol 6:21–25PubMedPubMedCentral Akin Y, Yucel S (2014) Long-term effects of pediatric extracorporeal shockwave lithotripsy on renal function. Res Rep Urol 6:21–25PubMedPubMedCentral
12.
Zurück zum Zitat Ozden E, Mercimek MN (2016) Percutaneous nephrolithotomy in pediatric age group: assessment of effectiveness and complications. World J Nephrol 5(1):84–89CrossRefPubMedPubMedCentral Ozden E, Mercimek MN (2016) Percutaneous nephrolithotomy in pediatric age group: assessment of effectiveness and complications. World J Nephrol 5(1):84–89CrossRefPubMedPubMedCentral
13.
Zurück zum Zitat Unsal A, Resorlu B, Kara C et al (2010) Safety and efficacy of percutaneous nephrolithotomy in infants, preschool age, and older children with different sizes of instruments. Urology 76:247–252CrossRefPubMed Unsal A, Resorlu B, Kara C et al (2010) Safety and efficacy of percutaneous nephrolithotomy in infants, preschool age, and older children with different sizes of instruments. Urology 76:247–252CrossRefPubMed
14.
Zurück zum Zitat Samad L, Qureshi S, Zaidi ZJ (2007) Does percutaneous nephrolithotomy in children cause significant renal scarring? Pediatric Urol 3:36–39CrossRef Samad L, Qureshi S, Zaidi ZJ (2007) Does percutaneous nephrolithotomy in children cause significant renal scarring? Pediatric Urol 3:36–39CrossRef
15.
Zurück zum Zitat D’Souza N, Paul S (2016) Mini percutaneous nephrolithotomy for renal calculi in pediatric patients: a review of twenty cases. Urol Ann 8:16–19CrossRefPubMedPubMedCentral D’Souza N, Paul S (2016) Mini percutaneous nephrolithotomy for renal calculi in pediatric patients: a review of twenty cases. Urol Ann 8:16–19CrossRefPubMedPubMedCentral
16.
Zurück zum Zitat Karatag T, Tepeler A, Silay MS, Bodakci MN, Buldu I, Daggulli M, Hatipoglu NK, Istanbulluoglu MO, Armagan A (2015) A comparison of 2 percutaneous nephrolithotomy techniques for the treatment of pediatric kidney stones of sizes 10–20 mm: microperc vs miniperc. Urology 85(5):1015–1018CrossRefPubMed Karatag T, Tepeler A, Silay MS, Bodakci MN, Buldu I, Daggulli M, Hatipoglu NK, Istanbulluoglu MO, Armagan A (2015) A comparison of 2 percutaneous nephrolithotomy techniques for the treatment of pediatric kidney stones of sizes 10–20 mm: microperc vs miniperc. Urology 85(5):1015–1018CrossRefPubMed
17.
Zurück zum Zitat El-Sheemy MS, Daw K, Habib E, Aboulela W, Fathy H, Shouman AM, El Ghoneimy M, Shoukry AI, Morsi HA, Badawy H (2016) Lower calyceal and renal pelvic stones in preschool children: a comparative study of mini-percutaneous nephrolithotomy versus extracorporeal shockwave lithotripsy, Division of Pediatric Urology, Aboul-Riche Children’s Hospital, Cairo University, Cairo, Egypt. Int J Urol 23(7):564–570CrossRef El-Sheemy MS, Daw K, Habib E, Aboulela W, Fathy H, Shouman AM, El Ghoneimy M, Shoukry AI, Morsi HA, Badawy H (2016) Lower calyceal and renal pelvic stones in preschool children: a comparative study of mini-percutaneous nephrolithotomy versus extracorporeal shockwave lithotripsy, Division of Pediatric Urology, Aboul-Riche Children’s Hospital, Cairo University, Cairo, Egypt. Int J Urol 23(7):564–570CrossRef
18.
Zurück zum Zitat Badawy AA, Saleem MD, Abolyosr A, Aldahshoury M, Elbadry MS, Abdalla MA (2012) Extracorporeal shock wave lithotripsy as first line treatment for urinary tract stones in children: outcome of 500 cases. Int Urol Nephrol 44:661–666CrossRefPubMed Badawy AA, Saleem MD, Abolyosr A, Aldahshoury M, Elbadry MS, Abdalla MA (2012) Extracorporeal shock wave lithotripsy as first line treatment for urinary tract stones in children: outcome of 500 cases. Int Urol Nephrol 44:661–666CrossRefPubMed
19.
Zurück zum Zitat Tze MW, Kidger L, Kennish S, Irving H, Najmaldin A (2013) MINI PCNL in a pediatric population. Cardiovasc Intervent Radiol 36:249–254 Tze MW, Kidger L, Kennish S, Irving H, Najmaldin A (2013) MINI PCNL in a pediatric population. Cardiovasc Intervent Radiol 36:249–254
20.
Zurück zum Zitat Zeng G, Zhao Z, Wan S, Zhong W, Wu W (2013) Comparison of children versus adults undergoing mini-percutaneous nephrolithotomy: large-scale analysis of a single institution. PLoS One 8:e66850CrossRefPubMedPubMedCentral Zeng G, Zhao Z, Wan S, Zhong W, Wu W (2013) Comparison of children versus adults undergoing mini-percutaneous nephrolithotomy: large-scale analysis of a single institution. PLoS One 8:e66850CrossRefPubMedPubMedCentral
21.
Zurück zum Zitat Resorlu B, Unsal A, Tepeler A, Atis G, Tokatli Z, Oztuna D, Armagan A (2012) Comparison of retrograde intrarenal surgery and mini-percutaneous nephrolithotomy in children with moderate-size kidney stones: results of multi-institutional analysis. Urology 80:519–523CrossRefPubMed Resorlu B, Unsal A, Tepeler A, Atis G, Tokatli Z, Oztuna D, Armagan A (2012) Comparison of retrograde intrarenal surgery and mini-percutaneous nephrolithotomy in children with moderate-size kidney stones: results of multi-institutional analysis. Urology 80:519–523CrossRefPubMed
22.
Zurück zum Zitat Hatipoglu NK, Sancaktutar AA, Tepeler A, Bodakci MN, Penbegul N, Atar M, Bozkurt Y, Soylemez H, Silay MS, Istanbulluoglu MO, Akman T, Armagan A (2013) Comparison of shockwave lithotripsy and microperc for treatment of kidney stones in children. J Endourol 27(9):1141–1146CrossRefPubMed Hatipoglu NK, Sancaktutar AA, Tepeler A, Bodakci MN, Penbegul N, Atar M, Bozkurt Y, Soylemez H, Silay MS, Istanbulluoglu MO, Akman T, Armagan A (2013) Comparison of shockwave lithotripsy and microperc for treatment of kidney stones in children. J Endourol 27(9):1141–1146CrossRefPubMed
23.
Zurück zum Zitat Salem HK, Fathy H, ElFayoumy H, Aly H, Ghonium A, Mohsen MA, Hegazy AE (2014) Slow vs rapid delivery rate shock wave lithotripsy for pediatric renal urolithiasis: a prospective randomized study. J Urol 191:1370–1374CrossRefPubMed Salem HK, Fathy H, ElFayoumy H, Aly H, Ghonium A, Mohsen MA, Hegazy AE (2014) Slow vs rapid delivery rate shock wave lithotripsy for pediatric renal urolithiasis: a prospective randomized study. J Urol 191:1370–1374CrossRefPubMed
24.
Zurück zum Zitat Jee JY, Kim SD, Cho WY (2013) Efficacy of extracorporeal shock wave lithotripsy in pediatric and adolescent urolithiasis. Korean J Urol 54:865–869CrossRefPubMedPubMedCentral Jee JY, Kim SD, Cho WY (2013) Efficacy of extracorporeal shock wave lithotripsy in pediatric and adolescent urolithiasis. Korean J Urol 54:865–869CrossRefPubMedPubMedCentral
25.
Zurück zum Zitat Lei H, Sun X, Lu J, Cong X, Zhu H, Shen L, Wang Y (2011) Comparison of efficacy and safety of shockwave lithotripsy for upper urinary tract stones of different locations in children: a study of 311 cases. World J Urol 29:713–717CrossRef Lei H, Sun X, Lu J, Cong X, Zhu H, Shen L, Wang Y (2011) Comparison of efficacy and safety of shockwave lithotripsy for upper urinary tract stones of different locations in children: a study of 311 cases. World J Urol 29:713–717CrossRef
26.
Zurück zum Zitat Yucel S, Akin Y, Danisman A, Guntekin E (2012) Complications and associated factors of pediatric extracorporeal shock wave lithotripsy. J Urol 187(5):1812–1816CrossRefPubMed Yucel S, Akin Y, Danisman A, Guntekin E (2012) Complications and associated factors of pediatric extracorporeal shock wave lithotripsy. J Urol 187(5):1812–1816CrossRefPubMed
27.
Zurück zum Zitat El-Nahas AR, El-Assmy AM, Awad BA, Elhalwagy SM, Elshal AM, Sheir KZ (2013) Extracorporeal shockwave lithotripsy for renal stones in pediatric patients: a multivariate analysis model for estimating the stone-free probability. Int J Urol 20(12):1205–1210CrossRefPubMed El-Nahas AR, El-Assmy AM, Awad BA, Elhalwagy SM, Elshal AM, Sheir KZ (2013) Extracorporeal shockwave lithotripsy for renal stones in pediatric patients: a multivariate analysis model for estimating the stone-free probability. Int J Urol 20(12):1205–1210CrossRefPubMed
28.
Zurück zum Zitat El-Assmy A, El-Nahas AR, Elsaadany MM, EL-Halwagy S, Sheir K (2015) Risk factors for formation of steinstrasse after extracorporeal shock wave lithotripsy for pediatric renal calculi: a multivariate analysis model. Int Urol Nephrol 47:573–577CrossRefPubMed El-Assmy A, El-Nahas AR, Elsaadany MM, EL-Halwagy S, Sheir K (2015) Risk factors for formation of steinstrasse after extracorporeal shock wave lithotripsy for pediatric renal calculi: a multivariate analysis model. Int Urol Nephrol 47:573–577CrossRefPubMed
29.
Zurück zum Zitat Kumar A, Kumar N, Vasudeva P, Kumar R, Jha SK, Singh H (2015) A single center experience comparing miniperc and Shock wave lithotripsy (SWL) for treatment of radioopaque 1–2 cm lower calyceal renal calculi in children: a prospective randomized study. J Endourol 29:805–809CrossRefPubMed Kumar A, Kumar N, Vasudeva P, Kumar R, Jha SK, Singh H (2015) A single center experience comparing miniperc and Shock wave lithotripsy (SWL) for treatment of radioopaque 1–2 cm lower calyceal renal calculi in children: a prospective randomized study. J Endourol 29:805–809CrossRefPubMed
30.
Zurück zum Zitat Onal B, Dogan HS, Satar N, Bilen CY, Güneş A, Ozden E (2014) Factors affecting complication rates of percutaneous nephrolithotomy in children: results of a multi-institutional retrospective analysis by the pediatric stone disease study group of the Turkish pediatric urology society. J Urol 191(3):777–782CrossRefPubMed Onal B, Dogan HS, Satar N, Bilen CY, Güneş A, Ozden E (2014) Factors affecting complication rates of percutaneous nephrolithotomy in children: results of a multi-institutional retrospective analysis by the pediatric stone disease study group of the Turkish pediatric urology society. J Urol 191(3):777–782CrossRefPubMed
Metadaten
Titel
Is mini-percutaneous nephrolithotomy a safe alternative to extracorporeal shockwave lithotripsy in pediatric age group in borderline stones? a randomized prospective study
verfasst von
Ahmed Farouk
Ahmed Tawfick
Mohamed Shoeb
Mahmoud A. Mahmoud
Diaa Eldin Mostafa
Mohamed Hasan
Hany M. Abdalla
Publikationsdatum
15.02.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
World Journal of Urology / Ausgabe 7/2018
Print ISSN: 0724-4983
Elektronische ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-018-2231-9

Weitere Artikel der Ausgabe 7/2018

World Journal of Urology 7/2018 Zur Ausgabe

„Überwältigende“ Evidenz für Tripeltherapie beim metastasierten Prostata-Ca.

22.05.2024 Prostatakarzinom Nachrichten

Patienten mit metastasiertem hormonsensitivem Prostatakarzinom sollten nicht mehr mit einer alleinigen Androgendeprivationstherapie (ADT) behandelt werden, mahnt ein US-Team nach Sichtung der aktuellen Datenlage. Mit einer Tripeltherapie haben die Betroffenen offenbar die besten Überlebenschancen.

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

Alphablocker schützt vor Miktionsproblemen nach der Biopsie

16.05.2024 alpha-1-Rezeptorantagonisten Nachrichten

Nach einer Prostatabiopsie treten häufig Probleme beim Wasserlassen auf. Ob sich das durch den periinterventionellen Einsatz von Alphablockern verhindern lässt, haben australische Mediziner im Zuge einer Metaanalyse untersucht.

Klinikreform soll zehntausende Menschenleben retten

15.05.2024 Klinik aktuell Nachrichten

Gesundheitsminister Lauterbach hat die vom Bundeskabinett beschlossene Klinikreform verteidigt. Kritik an den Plänen kommt vom Marburger Bund. Und in den Ländern wird über den Gang zum Vermittlungsausschuss spekuliert.

Update Urologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.