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13.05.2016 | Original Article

Sleep disorders and oral health: a cross-sectional study

verfasst von: Maria Clotilde Carra, Audrey Schmitt, Frederique Thomas, Nicolas Danchin, Bruno Pannier, Philippe Bouchard

Erschienen in: Clinical Oral Investigations | Ausgabe 4/2017

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Abstract

Objectives

Sleep disorders (SDs), particularly sleep deprivation, may alter the immune system and induce systemic inflammation. Recent evidence supports an association between SDs and periodontal diseases. This cross-sectional epidemiological study aims to compare oral health variables, such as the amount of plaque/calculus, gingival inflammation, and masticatory function, in individuals with and without SDs.

Materials and methods

The study population consisted in a French cohort of individuals who underwent medical and oral examinations between 2012 and 2013. Multivariate logistic regression and general linear models were used for group comparisons.

Results

Over a total of 29,870 individuals, 11,185 (37.4 %) reported to suffer from SDs on a regular basis. Compared to individuals without SDs, SD individuals were older (mean age 44.2 vs. 45.3 years; p < 0.0001), prevalently female (38.6 vs. 52.1 %; p < 0.0001), and with higher BMI (25.3 vs. 25.7; p < 0.0001). Moreover, SD individuals displayed a significantly higher prevalence of comorbidities, higher level of gingival inflammation (adjusted odds ratio 1.22 [95 % confidence interval 1.13–1.32]), and lower masticatory function (1.45 [1.33–1.58]). Short sleepers (<6 h of sleep/night) were found to be at an increased risk of gingival inflammation (1.25 [1.1–1.4]). SD individuals with moderate-to-high gingival inflammation showed a significantly increased risk of cardiovascular disease (1.39 [1.04–1.84]) compared to SD individuals with low or no gingival inflammation.

Conclusions

Individuals with self-report SDs are at increased risk of gingival inflammation. The coexistence of SDs and gingival inflammation is associated with an increased risk of cardiovascular diseases.

Clinical relevance

These findings provide evidence for an association between SDs and gingival inflammation and support further clinical and experimental studies.

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Titel: Sleep disorders and oral health: a cross-sectional study
verfasst von: Maria Clotilde Carra
Audrey Schmitt
Frederique Thomas
Nicolas Danchin
Bruno Pannier
Philippe Bouchard
Publikationsdatum: 13.05.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: Clinical Oral Investigations / Ausgabe 4/2017
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-016-1851-y

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Sleep disorders and oral health: a cross-sectional study