nach oben

Erschienen in:

17.11.2020 | Original Article

Effect of cyanoacrylate tissue adhesive in postoperative palatal pain management: a systematic review

verfasst von: Mario Escobar, Patrícia Pauletto, Cesar Augusto Magalhães Benfatti, Ariadne Cristiane Cabral Cruz, Carlos Flores-Mir, Bruno Alexandre Pacheco Castro Henriques

Erschienen in: Clinical Oral Investigations | Ausgabe 6/2021

Einloggen, um Zugang zu erhalten

Abstract

Objective

To critically appraise available literature concerning the effect of cyanoacrylate tissue adhesive (CTA) in postoperative palatal pain management.

Materials and methods

Electronic databases (Cochrane, PubMed, LILACS, Scopus, and Web of Science) were searched, complemented with grey literature databases up to June 2020. Studies reporting the effect of cyanoacrylate tissue adhesive compared to any other methods in postoperative palatal pain management were considered eligible. The risk of bias among and across included studies was assessed.

Results

Finally, four studies were considered eligible. Regarding free gingival graft (FGG), cyanoacrylate tissue adhesive with hemostatic sponge promoted less postoperative pain (PP) and analgesic consumption (AC). Also, cyanoacrylate tissue adhesive with platelet-rich fibrin produced less PP and more wound healing at the palatal area than cyanoacrylate tissue adhesive and wet gauze. Additionally, cyanoacrylate tissue adhesive promoted less PP and AC than wet gauze and suture. Concerning connective tissue graft (CTG), cyanoacrylate tissue adhesive, and suture produced similar PP, AC, and willingness for retreatment.

Conclusions

Based on the low certainty level, cyanoacrylate tissue adhesive appears to promote less PP and AC than wet gauze and suture regarding FGG. Additionally, cyanoacrylate tissue adhesive appears to increase the effect of hemostatic sponge, contributing to the reduction of PP and AC. Regarding CTG, cyanoacrylate tissue adhesive appears to promote similar PP, AC, and willingness for retreatment than the suture. Therefore, cyanoacrylate tissue adhesive has shown promising usefulness for PP management in FGG, but not a clear benefit for CTG.

Clinical relevance

The adoption of different agents for the protection of the palatal donor site following gingival harvesting procedures may provide better comfort to the patient.

Nur mit Berechtigung zugänglich

Cairo F (2017) Periodontal plastic surgery of gingival recessions at single and multiple teeth. Periodontol 75(1):296–316. https://doi.org/10.1111/prd.12186CrossRef

Zucchelli G, Tavelli L, McGuire MK et al (2020) Autogenous soft tissue grafting for periodontal and peri-implant plastic surgical reconstruction. J Periodontol 91(1):9–16. https://doi.org/10.1002/JPER.19-0350CrossRefPubMed

Zucchelli G, Mounssif I, Mazzotti C et al (2014) Does the dimension of the graft influence patient morbidity and root coverage outcomes? A randomized controlled clinical trial. J Clin Periodontol 41(7):708–716. https://doi.org/10.1111/jcpe.12256CrossRefPubMed

Keceli HG, Aylikci BU, Koseoglu S, Dolgun A (2015) Evaluation of palatal donor site haemostasis and wound healing after free gingival graft surgery. J Clin Periodontol 42(6):582–589. https://doi.org/10.1111/jcpe.12404CrossRefPubMed

Madi M, Kassem A (2018) Topical simvastatin gel as a novel therapeutic modality for palatal donor site wound healing following free gingival graft procedure. Acta Odontol Scand 76(3):212–219. https://doi.org/10.1080/00016357.2017.1403648CrossRefPubMed

Ozcan-Kucuk A, Alan H, Gul M, Yolcu U (2018) Evaluating the effect of resveratrol on the healing of extraction sockets in cyclosporine a–treated rats. J Oral Maxillofac Surg 76(7):1404–1413. https://doi.org/10.1016/j.joms.2018.02.030CrossRefPubMed

Stavropoulou C, Atout RN, Brownlee M et al (2019) A randomized clinical trial of cyanoacrylate tissue adhesives in donor site of connective tissue grafts. J Periodontol 90(6):608–615. https://doi.org/10.1002/JPER.18-0475CrossRefPubMed

Tavelli L, Asa’ad F, Acunzo R et al (2018) Minimizing patient morbidity following palatal gingival harvesting: a randomized controlled clinical study. Int J Periodontics Restorative Dent 38(6):e127–e134. https://doi.org/10.11607/prd.3581CrossRefPubMed

Tavelli L, Ravidà A, Saleh MHAA et al (2019) Pain perception following epithelialized gingival graft harvesting: a randomized clinical trial. Clin Oral Investig 23(1):459–468. https://doi.org/10.1007/s00784-018-2455-5CrossRefPubMed

10.

Rossberg M, Dent M (2008) Long-term results of root coverage with connective tissue in the envelope technique: a report of 20 cases. Int J Periodontics Restorative Dent 28(1):19–27

11.

Nevins M, Mendoza-Azpur G, De Angelis N, Kim D (2018) The biocompatibility of cyanoacrylate tissue adhesive in conjunction with a collagen membrane for providing soft and hard tissue regeneration in extraction socket preservation procedures. Int J Periodontics Restorative Dent 38s37–s42. https://doi.org/10.11607/prd.3770

12.

Singer AJ, Quinn JV, Hollander JE (2008) The cyanoacrylate topical skin adhesives. Am J Emerg Med 26(4):490–496. https://doi.org/10.1016/j.ajem.2007.05.015CrossRefPubMed

13.

Rewainy M, Osman S (2015) The use of N-butyl cyanoacrylate adhesive in the closure of muco- periosteal flap after the surgical extraction of impacted mandibular third molar. Alexandria Dent J 40(PeriAcryl 90):152–159CrossRef

14.

Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 151(4):264–269CrossRef

15.

Stone PW (2002) Popping the (PICO) question in research and evidence-based practice. Appl Nurs Res 15(3):197–198. https://doi.org/10.1053/apnr.2002.34181CrossRefPubMed

16.

Tufanaru C, Munn Z, Aromataris E et al (2017) Chapter 3: Systematic reviews of effectiveness. In: Aromataris E, Munn Z (eds). Joanna Briggs Institute Reviewer’s Manual. Joanna Briggs Inst

17.

Manheimer E (2012) Summary of findings tables: presenting the main findings of cochrane complementary and alternative medicine–related reviews in a transparent and simple tabular format. Glob Adv Health Med 1(1):90CrossRef

18.

Ozcan M, Ucak O, Alkaya B et al (2017) Effects of platelet-rich fibrin on palatal wound healing after free gingival graft harvesting: a comparative randomized controlled clinical trial. Int J Periodontics Restorative Dent 37(5):e270–e278. https://doi.org/10.11607/prd.3226CrossRefPubMed

19.

Zucchelli G, Mele M, Stefanini M et al (2010) Patient morbidity and root coverage outcome after subepithelial connective tissue and de-epithelialized grafts: a comparative randomized-controlled clinical trial. J Clin Periodontol 37(8):728–738. https://doi.org/10.1111/j.1600-051X.2010.01550.xCrossRefPubMed

20.

Gobbato L, Nart J, Bressan E et al (2016) Patient morbidity and root coverage outcomes after the application of a subepithelial connective tissue graft in combination with a coronally advanced flap or via a tunneling technique: a randomized controlled clinical trial. Clin Oral Investig 20(8):2191–2202. https://doi.org/10.1007/s00784-016-1721-7CrossRefPubMed

21.

Wyrębek B, Górski B, Górska R et al (2018) Patient morbidity at the palatal donor site depending on gingival graft dimension. Dent Med Probl 55(2):153–159. https://doi.org/10.17219/dmp/91406CrossRefPubMed

22.

Chiu T-S, Chou H-C, Kuo P-J et al (2020) A novel design of palatal stent to reduce donor site morbidity in periodontal plastic surgery. J Dent Sci 15(2):136–140. https://doi.org/10.1016/j.jds.2020.03.014CrossRefPubMedPubMedCentral

23.

Leggat PA, Kedjarune U, Smith DR (2004) Toxicity of cyanoacrylate adhesives and their occupational impacts for dental staff. Ind Health 42(2):207–211. https://doi.org/10.2486/indhealth.42.207CrossRefPubMed

24.

Aksoy F, Yilmaz F, Yildirim YS et al (2010) Use of N-butyl cyanoacrylate in nasal septoplasty: histopathological evaluation using rabbit nasal septum model. J Laryngol Otol 124(7):753–758. https://doi.org/10.1017/S0022215110000095CrossRefPubMed

25.

Eggers MD, Fang L, Lionberger DR (2011) A comparison of wound closure techniques for total knee arthroplasty. J Arthroplast 26(8):1251–1254. https://doi.org/10.1016/j.arth.2011.02.029CrossRef

26.

Nguyen AJ, Baron TH, Burgart LJ et al (2002) 2-Octyl-cyanoacrylate (Dermabond), a new glue for variceal injection therapy: results of a preliminary animal study. Gastrointest Endosc 55(4):572–575. https://doi.org/10.1067/mge.2002.122032CrossRefPubMed

27.

Pérez M, Fernández I, Márquez D et al (2000) Use of N-butyl-2-cyanoacrylate in oral surgery: biological and clinical evaluation. Artif Organs 24(3):241–243. https://doi.org/10.1046/j.1525-1594.2000.06519.xCrossRefPubMed

28.

Femminella B, Iaconi MC, Di Tullio M et al (2016) Clinical comparison of platelet-rich fibrin and a gelatin sponge in the management of palatal wounds after epithelialized free gingival graft harvest: a randomized clinical trial. J Periodontol 87(2):103–113. https://doi.org/10.1902/jop.2015.150198CrossRefPubMed

29.

Jain V, Triveni MG, Kumar ABT, Mehta DS (2012) Role of platelet-rich-fibrin in enhancing palatal wound healing after free graft. Contemp Clin Dent 3(Suppl 2):S240–S243. https://doi.org/10.4103/0976-237X.101105CrossRefPubMedPubMedCentral

30.

Guyatt GH, Oxman AD, Vist GE et al (2008) GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 336(7650):924–926. https://doi.org/10.1136/bmj.39489.470347.ADCrossRefPubMedPubMedCentral

Titel: Effect of cyanoacrylate tissue adhesive in postoperative palatal pain management: a systematic review
verfasst von: Mario Escobar
Patrícia Pauletto
Cesar Augusto Magalhães Benfatti
Ariadne Cristiane Cabral Cruz
Carlos Flores-Mir
Bruno Alexandre Pacheco Castro Henriques
Publikationsdatum: 17.11.2020
Verlag: Springer Berlin Heidelberg
Erschienen in: Clinical Oral Investigations / Ausgabe 6/2021
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-020-03683-w

Update Zahnmedizin

Bestellen Sie unseren kostenlosen Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.

Newsletter bestellen

Springer Medizin

Effect of cyanoacrylate tissue adhesive in postoperative palatal pain management: a systematic review