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Erschienen in: Journal of Cutaneous Medicine and Surgery 1/2005

01.02.2005 | Case Report

Combined Merkel Cell Carcinoma and Atypical Fibroxanthoma

verfasst von: Summer R. Youker, Elizabeth M. Billingsley

Erschienen in: Journal of Cutaneous Medicine and Surgery | Ausgabe 1/2005

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Abstract

Background

Although there are reports of squamous cell carcinoma arising within and adjacent to Merkel cell carcinoma, and one report of an atypical fibroxanthoma-like tumor arising in an irradiated recurrent Merkel cell carcinoma, there have previously been no reports of an immunohistochemically verified atypical fibroxanthoma occurring in conjunction with a Merkel cell carcinoma.

Objective

We report on a neoplasm with distinct features of both Merkel cell carcinoma and atypical fibroxanthoma.

Methods

Histologic and immunohistochemical evaluations were performed.

Results

Our results verify the finding of a combined Merkel cell carcinoma and atypical fibroxanthoma.

Conclusion

This case is an interesting and unusual combination of tumors. The origin of the Merkel cell carcinoma is revisited. Debated origins include neuroendocrine, epithelial, and pleuripotent stem cell.
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Metadaten
Titel
Combined Merkel Cell Carcinoma and Atypical Fibroxanthoma
verfasst von
Summer R. Youker
Elizabeth M. Billingsley
Publikationsdatum
01.02.2005
Erschienen in
Journal of Cutaneous Medicine and Surgery / Ausgabe 1/2005
Print ISSN: 1203-4754
Elektronische ISSN: 1615-7109
DOI
https://doi.org/10.1007/s10227-005-0024-4

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